Time’s up: mutation rate and lifespan by Anjali Cremer, Wesley T. Abplanalp, Michael A. Rieger

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Stem Cell Hierarchy and Clonal Evolution in Acute Lymphoblastic Leukemia by Fabian Lang, Bartosch Wojcik, Michael A. Rieger

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MEKK1 Regulates Chemokine Expression in Mammary Fibroblasts: Implications for the Breast Tumor Microenvironment by Saverio Gentile, Najmeh Eskandari, Michael A. Rieger, Bruce D. Cuevas

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Group and Individual Variability in Mouse Pup Isolation Calls Recorded on the Same Day Show Stability by Terra D. Barnes, Michael A. Rieger, Joseph D. Dougherty, Timothy E. Holy

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Delayed Mesoderm and Erythroid Differentiation of Murine Embryonic Stem Cells in the Absence of the Transcriptional Regulator FUBP1 by Josephine Wesely, Marlene Steiner, Frank Schnütgen, Manuel Kaulich, Michael A. Rieger, Martin Zörnig

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Dopamine signaling regulates predator-driven changes in Caenorhabditis elegans’ egg laying behavior by Amy Pribadi, Michael A Rieger, Kaila Rosales, Kirthi C Reddy, Sreekanth H Chalasani

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Loss of Quaking RNA binding protein disrupts the expression of genes associated with astrocyte maturation in mouse brain by Kristina Sakers, Yating Liu, Lorida Llaci, Scott M. Lee, Michael J. Vasek, Michael A. Rieger, Sean Brophy, Eric Tycksen, Renate Lewis, Susan E. Maloney, Joseph D. Dougherty

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HIV-1 Infection of Long-Lived Hematopoietic Precursors In Vitro and In Vivo by Sebastian Renelt, Patrizia Schult-Dietrich, Hanna-Mari Baldauf, Stefan Stein, Gerrit Kann, Markus Bickel, Ulrikke Kielland-Kaisen, Halvard Bonig, Rolf Marschalek, Michael A. Rieger, Ursula Dietrich, Ralf Duerr

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Continuous map of early hematopoietic stem cell differentiation across human lifetime by Hana Komic, Tessa Schmachtel, Catia Simoes, Marius Külp, Weijia Yu, Adrien Jolly, Malin S. Nilsson, Carmen Gonzalez, Felipe Prosper, Halvard Bonig, Bruno Paiva, Fredrik B. Thorén, Michael A. Rieger

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Hematopoietic alterations in chronic heart failure patients by somatic mutations leading to clonal hematopoiesis by Lena Dorsheimer, Birgit Assmus, Tina Rasper, Christina A. Ortmann, Khalil Abou-El-Ardat, Katharina C. Kiefer, Jedrzej Hoffmann, Florian Seeger, Halvard Bonig, Stefanie Dimmeler, Andreas M. Zeiher, Michael A. Rieger

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Single-Stranded DNA-Binding Transcriptional Regulator FUBP1 Is Essential for Fetal and Adult Hematopoietic Stem Cell Self-Renewal by Uta Rabenhorst, Frederic B. Thalheimer, Katharina Gerlach, Marek Kijonka, Stefanie Böhm, Daniela S. Krause, Franz Vauti, Hans-Henning Arnold, Timm Schroeder, Frank Schnütgen, Harald von Melchner, Michael A. Rieger, Martin Zörnig

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Full spectrum of clonal haematopoiesis‐driver mutations in chronic heart failure and their associations with mortality by Katharina C. Kiefer, Sebastian Cremer, Evangelia Pardali, Birgit Assmus, Khalil Abou‐El‐Ardat, Klara Kirschbaum, Lena Dorsheimer, Tina Rasper, Alexander Berkowitsch, Hubert Serve, Stefanie Dimmeler, Andreas M. Zeiher, Michael A. Rieger

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The Phosphatases STS1 and STS2 Regulate Hematopoietic Stem and Progenitor Cell Fitness by Jing Zhang, Olesya Vakhrusheva, Srinivasa Rao Bandi, Özlem Demirel, Julhash U. Kazi, Ramona Gomes Fernandes, Katja Jakobi, Astrid Eichler, Lars Rönnstrand, Michael A. Rieger, Nick Carpino, Hubert Serve, Christian H. Brandts

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P1354: CRISPR/CAS9 GENE EDITING OF IMMUNE CHECKPOINT RECEPTOR NKG2A IMPROVES THE ANTI-LEUKEMIC EFFICACY OF PRIMARY CD33-TARGETING CAR-NK CELLS. by Nawid Albinger, Tobias Bexte, Ahmad Al-Ajami, Philipp Wendel, Leon Buchinger, Alec Gessner, Jamal Alzubi, Vinzenz Särchen, Meike Vogler, Raj Bhayadia, Jan-Henning Klusmann, Nina Möker, Toni Cathomen, Michael A. Rieger, Katharina Imkeller, Evelyn Ullrich

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The NADPH organizers NoxO1 and p47phox are both mediators of diabetes-induced vascular dysfunction in mice by Flávia Rezende, Franziska Moll, Maria Walter, Valeska Helfinger, Fabian Hahner, Patrick Janetzko, Christian Ringel, Andreas Weigert, Ingrid Fleming, Norbert Weissmann, Carsten Kuenne, Mario Looso, Michael A. Rieger, Peter Nawroth, Thomas Fleming, Ralf P. Brandes, Katrin Schröder

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Wnt/β-Catenin-Signaling Modulates Megakaryopoiesis at the Megakaryocyte-Erythrocyte Progenitor Stage in the Hematopoietic System by Burak H. Yalcin, Jadranka Macas, Eliza Wiercinska, Patrick N. Harter, Malak Fawaz, Tessa Schmachtel, Ilaria Ghiro, Ewa Bieniek, Djuro Kosanovic, Sonja Thom, Marcus Fruttiger, Makoto M. Taketo, Ralph T. Schermuly, Michael A. Rieger, Karl H. Plate, Halvard Bonig, Stefan Liebner

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An alternative CYB5A transcript is expressed in aneuploid ALL and enriched in relapse by Lorenz Bartsch, Michael P. Schroeder, Sonja Hänzelmann, Lorenz Bastian, Juan Lázaro-Navarro, Cornelia Schlee, Jutta Ortiz Tanchez, Veronika Schulze, Konstandina Isaakidis, Michael A. Rieger, Nicola Gökbuget, Cornelia Eckert, Hubert Serve, Martin Horstmann, Martin Schrappe, Monika Brüggemann, Claudia D. Baldus, Martin Neumann

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A Cre-dependent massively parallel reporter assay allows for cell-type specific assessment of the functional effects of non-coding elements in vivo by Tomas Lagunas, Stephen P. Plassmeyer, Anthony D. Fischer, Ryan Z. Friedman, Michael A. Rieger, Din Selmanovic, Simona Sarafinovska, Yvette K. Sol, Michael J. Kasper, Stuart B. Fass, Alessandra F. Aguilar Lucero, Joon-Yong An, Stephan J. Sanders, Barak A. Cohen, Joseph D. Dougherty

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Association of Clonal Hematopoiesis of Indeterminate Potential with Inflammatory Gene Expression in Patients with COPD by Stefan Kuhnert, Siavash Mansouri, Michael A. Rieger, Rajkumar Savai, Edibe Avci, Gabriela Díaz-Piña, Manju Padmasekar, Mario Looso, Stefan Hadzic, Till Acker, Stephan Klatt, Jochen Wilhelm, Ingrid Fleming, Natascha Sommer, Norbert Weissmann, Claus Vogelmeier, Robert Bals, Andreas Zeiher, Stefanie Dimmeler, Werner Seeger, Soni S. Pullamsetti

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RUNX1 interacts with lncRNA SMANTIS to regulate monocytic cell functions by Lisa M. Weiss, Timothy Warwick, Simonida Zehr, Stefan Günther, Sebastian Wolf, Tessa Schmachtel, Judit Izquierdo Ponce, Katalin Pálfi, Tom Teichmann, Alicia Schneider, Julia Stötzel, Stefan Knapp, Andreas Weigert, Rajkumar Savai, Michael A. Rieger, Thomas Oellerich, Ilka Wittig, James A. Oo, Ralf P. Brandes, Matthias S. Leisegang

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