Broad and Protective Influenza B Virus Neuraminidase Antibodies in Humans after Vaccination and their Clonal Persistence as Plasma Cells by Michael S. Piepenbrink, Aitor Nogales, Madhubanti Basu, Christopher F. Fucile, Jane L. Liesveld, Michael C. Keefer, Alexander F. Rosenberg, Luis Martinez-Sobrido, James J. Kobie

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Curaxin CBL0100 Blocks HIV-1 Replication and Reactivation through Inhibition of Viral Transcriptional Elongation by Maxime J. Jean, Tsuyoshi Hayashi, Huachao Huang, Justin Brennan, Sydney Simpson, Andrei Purmal, Katerina Gurova, Michael C. Keefer, James J. Kobie, Netty G. Santoso, Jian Zhu, Jian Zhu

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Prospective surveillance for cardiac adverse events in healthy adults receiving modified vaccinia Ankara vaccines: a systematic review. by Marnie L Elizaga, Sandhya Vasan, Mary A Marovich, Alicia H Sato, Dale N Lawrence, Bernard R Chaitman, Sharon E Frey, Michael C Keefer, MVA Cardiac Safety Working Group

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Pre-existing neutralizing antibody mitigates B cell dysregulation and enhances the Env-specific antibody response in SHIV-infected rhesus macaques. by Juan Pablo Jaworski, Peter Bryk, Zachary Brower, Bo Zheng, Ann J Hessell, Alexander F Rosenberg, Tong Tong Wu, Ignacio Sanz, Michael C Keefer, Nancy L Haigwood, James J Kobie

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Bridging the Digital Divide in HIV Care by Amneris E. Luque MD, Roberto Corales DO, Richard J. Fowler, Jamie DiMarco MSW, Adjuah van Keken MA, Paul Winters MS, Michael C. Keefer MD, Kevin Fiscella MD, MPH

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Broad HIV epitope specificity and viral inhibition induced by multigenic HIV-1 adenovirus subtype 35 vector vaccine in healthy uninfected adults. by Jakub Kopycinski, Peter Hayes, Ambreen Ashraf, Hannah Cheeseman, Francesco Lala, Justyna Czyzewska-Khan, Aggeliki Spentzou, Dilbinder K Gill, Michael C Keefer, Jean-Louis Excler, Patricia Fast, Josephine Cox, Jill Gilmour

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House Ball Community Leaders’ Perceptions of HIV and HIV Vaccine Research by Amina P. Alio, PhD, Candace Sibley, MPH, Halimah S. Ouedraogo, BA, Stephaun E. Wallace, PhD, Steven Wakefield, BA, Damon L. Humes, MHS, Sheldon D. Fields, PhD, Michael C. Keefer, MD

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Daily fosfomycin versus levofloxacin for complicated urinary tract infections by Nadine Rouphael, Patricia Winokur, Michael C. Keefer, Jessica Traenkner, Ana Drobeniuc, Yohei Doi, Sonal Munsiff, Vance G. Fowler, Scott Evans, Randolph E. Oler, Bonifride Tuyishimire, Marina Lee, Varduhi Ghazaryan, Henry F. Chambers

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Persistence of HIV-1 Env-Specific Plasmablast Lineages in Plasma Cells after Vaccination in Humans by Madhubanti Basu, Michael S. Piepenbrink, Czestochowa Francois, Fritzlaine Roche, Bo Zheng, David A. Spencer, Ann J. Hessell, Christopher F. Fucile, Alexander F. Rosenberg, Catherine A. Bunce, Jane Liesveld, Michael C. Keefer, James J. Kobie

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SWIFT clustering analysis of intracellular cytokine staining flow cytometry data of the HVTN 105 vaccine trial reveals high frequencies of HIV-specific CD4+ T cell responses and as... by Tim R. Mosmann, Jonathan A. Rebhahn, Stephen C. De Rosa, Michael C. Keefer, M. Juliana McElrath, Nadine G. Rouphael, Giuseppe Pantaleo, Giuseppe Pantaleo, Peter B. Gilbert, Lawrence Corey, James J. Kobie, Juilee Thakar

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9G4 autoreactivity is increased in HIV-infected patients and correlates with HIV broadly neutralizing serum activity. by James J Kobie, Danielle C Alcena, Bo Zheng, Peter Bryk, Jonelle L Mattiacio, Matthew Brewer, Celia Labranche, Faith M Young, Stephen Dewhurst, David C Montefiori, Alexander F Rosenberg, Changyong Feng, Xia Jin, Michael C Keefer, Ignacio Sanz

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Immunization with cocktail of HIV-derived peptides in montanide ISA-51 is immunogenic, but causes sterile abscesses and unacceptable reactogenicity. by Barney S Graham, M Juliana McElrath, Michael C Keefer, Kyle Rybczyk, David Berger, Kent J Weinhold, Janet Ottinger, Guido Ferarri, David C Montefiori, Don Stablein, Carol Smith, Richard Ginsberg, John Eldridge, Ann Duerr, Pat Fast, Barton F Haynes, AIDS Vaccine Evaluation Group

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First-in-human randomized controlled trial of an oral, replicating adenovirus 26 vector vaccine for HIV-1. by Kathryn E Stephenson, Michael C Keefer, Catherine A Bunce, Doreen Frances, Peter Abbink, Lori F Maxfield, George H Neubauer, Joseph Nkolola, Lauren Peter, Christopher Lane, Harriet Park, Carl Verlinde, Angela Lombardo, Christopher Yallop, Menzo Havenga, Patricia Fast, John Treanor, Dan H Barouch

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A phase I double blind, placebo-controlled, randomized study of a multigenic HIV-1 adenovirus subtype 35 vector vaccine in healthy uninfected adults. by Michael C Keefer, Jill Gilmour, Peter Hayes, Dilbinder Gill, Jakub Kopycinski, Hannah Cheeseman, Michelle Cashin-Cox, Marloes Naarding, Lorna Clark, Natalia Fernandez, Catherine A Bunce, Christine M Hay, Sabrina Welsh, Wendy Komaroff, Lottie Hachaambwa, Tony Tarragona-Fiol, Eddy Sayeed, Devika Zachariah, James Ackland, Kelley Loughran, Burc Barin, Emmanuel Cormier, Josephine H Cox, Patricia Fast, Jean-Louis Excler

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Phase 1 safety and immunogenicity evaluation of ADVAX, a multigenic, DNA-based clade C/B' HIV-1 candidate vaccine. by Sandhya Vasan, Sarah J Schlesinger, Yaoxing Huang, Arlene Hurley, Angela Lombardo, Zhiwei Chen, Soe Than, Phumla Adesanya, Catherine Bunce, Mark Boaz, Rosanne Boyle, Eddy Sayeed, Lorna Clark, Daniel Dugin, Claudia Schmidt, Yang Song, Laura Seamons, Len Dally, Martin Ho, Carol Smith, Martin Markowitz, Josephine Cox, Dilbinder K Gill, Jill Gilmour, Michael C Keefer, Patricia Fast, David D Ho

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Effect of rAd5-Vector HIV-1 Preventive Vaccines on HIV-1 Acquisition: A Participant-Level Meta-Analysis of Randomized Trials. by Yunda Huang, Dean Follmann, Martha Nason, Lily Zhang, Ying Huang, Devan V Mehrotra, Zoe Moodie, Barbara Metch, Holly Janes, Michael C Keefer, Gavin Churchyard, Merlin L Robb, Patricia E Fast, Ann Duerr, M Juliana McElrath, Lawrence Corey, John R Mascola, Barney S Graham, Magdalena E Sobieszczyk, James G Kublin, Michael Robertson, Scott M Hammer, Glenda E Gray, Susan P Buchbinder, Peter B Gilbert

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Baseline host determinants of robust human HIV-1 vaccine-induced immune responses: A meta-analysis of 26 vaccine regimens by Yunda Huang, Yuanyuan Zhang, Kelly E. Seaton, Stephen De Rosa, Jack Heptinstall, Lindsay N. Carpp, April Kaur Randhawa, Lyle R. McKinnon, Paul McLaren, Edna Viegas, Glenda E. Gray, Gavin Churchyard, Susan P. Buchbinder, Srilatha Edupuganti, Linda-Gail Bekker, Michael C. Keefer, Mina C. Hosseinipour, Paul A. Goepfert, Kristen W. Cohen, Brian D. Williamson, M. Juliana McElrath, Georgia D. Tomaras, Juilee Thakar, James J. Kobie

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Phase 1 safety and immunogenicity evaluation of ADMVA, a multigenic, modified vaccinia Ankara-HIV-1 B'/C candidate vaccine. by Sandhya Vasan, Sarah J Schlesinger, Zhiwei Chen, Arlene Hurley, Angela Lombardo, Soe Than, Phumla Adesanya, Catherine Bunce, Mark Boaz, Rosanne Boyle, Eddy Sayeed, Lorna Clark, Daniel Dugin, Mar Boente-Carrera, Claudia Schmidt, Qing Fang, LeiBa, Yaoxing Huang, Gerasimos J Zaharatos, David F Gardiner, Marina Caskey, Laura Seamons, Martin Ho, Len Dally, Carol Smith, Josephine Cox, Dilbinder Gill, Jill Gilmour, Michael C Keefer, Patricia Fast, David D Ho

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A phase IIA randomized clinical trial of a multiclade HIV-1 DNA prime followed by a multiclade rAd5 HIV-1 vaccine boost in healthy adults (HVTN204). by Gavin J Churchyard, Cecilia Morgan, Elizabeth Adams, John Hural, Barney S Graham, Zoe Moodie, Doug Grove, Glenda Gray, Linda-Gail Bekker, M Juliana McElrath, Georgia D Tomaras, Paul Goepfert, Spyros Kalams, Lindsey R Baden, Michelle Lally, Raphael Dolin, William Blattner, Artur Kalichman, J Peter Figueroa, Jean Pape, Mauro Schechter, Olivier Defawe, Stephen C De Rosa, David C Montefiori, Gary J Nabel, Lawrence Corey, Michael C Keefer, NIAID HIV Vaccine Trials Network

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Polytopic fractional delivery of an HIV vaccine alters cellular responses and results in increased epitope breadth in a phase 1 randomized trialResearch in context by Maurine D. Miner, Allan deCamp, Nicole Grunenberg, Stephen C. De Rosa, Andrew Fiore-Gartland, Katherine Bar, Paul Spearman, Mary Allen, Pei-Chun Yu, Bryce Manso, Nicole Frahm, Spyros Kalams, Lindsey Baden, Michael C. Keefer, Hyman M. Scott, Richard Novak, Hong Van Tieu, Georgia D. Tomaras, James G. Kublin, M. Juliana McElrath, Lawrence Corey, Ian Frank, Artur Kalichman, Paul Edlefsen, Mary Enama, John Hural, Renee Holt, Debora Dunbar, Dave Crawford, Ian Maki, Jan Johannessen, Scharla Estep, Yevgeny Grigoriev, Tamra Madenwald, Marianne Hansen, Drienna Holman, Ramey Fair, Genevieve Meyer, Anya Luke-Kilolam

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