Accurate and cost-effective generation of a genetic risk score direct from blood lysates av Jonathan M. Locke, Benjamin Spurrier, Thomas W. Laver, Jayne A.L. Houghton, Kevin Colclough, Michael N. Weedon, Richard A. Oram

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Type 1 diabetes genetic risk score variation across ancestries using whole genome sequencing and array-based approaches av Ankit M. Arni, Diane P. Fraser, Seth A. Sharp, Richard A. Oram, Matthew B. Johnson, Michael N. Weedon, Kashyap A. Patel

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SavvyCNV: Genome-wide CNV calling from off-target reads. av Thomas W Laver, Elisa De Franco, Matthew B Johnson, Kashyap A Patel, Sian Ellard, Michael N Weedon, Sarah E Flanagan, Matthew N Wakeling

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A genome-wide association study identifies 5 loci associated with frozen shoulder and implicates diabetes as a causal risk factor. av Harry D Green, Alistair Jones, Jonathan P Evans, Andrew R Wood, Robin N Beaumont, Jessica Tyrrell, Timothy M Frayling, Christopher Smith, Michael N Weedon

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A genome-wide association study identifies 5 loci associated with frozen shoulder and implicates diabetes as a causal risk factor av Harry D. Green, Alistair Jones, Jonathan P. Evans, Andrew R. Wood, Robin N. Beaumont, Jessica Tyrrell, Timothy M. Frayling, Christopher Smith, Michael N. Weedon

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Identification and analysis of individuals who deviate from their genetically-predicted phenotype. av Gareth Hawkes, Loic Yengo, Sailaja Vedantam, Eirini Marouli, Robin N Beaumont, GIANT Consortium, Jessica Tyrrell, Michael N Weedon, Joel Hirschhorn, Timothy M Frayling, Andrew R Wood

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Estimating disease prevalence in large datasets using genetic risk scores av Benjamin D. Evans, Piotr Słowiński, Andrew T. Hattersley, Samuel E. Jones, Seth Sharp, Robert A. Kimmitt, Michael N. Weedon, Richard A. Oram, Krasimira Tsaneva-Atanasova, Nicholas J. Thomas

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Combining information from common type 2 diabetes risk polymorphisms improves disease prediction. av Michael N Weedon, Mark I McCarthy, Graham Hitman, Mark Walker, Christopher J Groves, Eleftheria Zeggini, N William Rayner, Beverley Shields, Katharine R Owen, Andrew T Hattersley, Timothy M Frayling

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Insights into the genetics of menopausal vasomotor symptoms: genome-wide analyses of routinely-collected primary care health records av Katherine S. Ruth, Robin N. Beaumont, Jonathan M. Locke, Jessica Tyrrell, Carolyn J. Crandall, Gareth Hawkes, Timothy M. Frayling, Julia K. Prague, Kashyap A. Patel, Andrew R. Wood, Michael N. Weedon, Anna Murray

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Correlations in sleeping patterns and circadian preference between spouses av Rebecca C. Richmond, Laurence J. Howe, Karl Heilbron, Samuel Jones, Junxi Liu, 23andMe Research Team, Xin Wang, Michael N. Weedon, Martin K. Rutter, Deborah A. Lawlor, George Davey Smith, Céline Vetter

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Sleep classification from wrist-worn accelerometer data using random forests av Kalaivani Sundararajan, Sonja Georgievska, Bart H. W. te Lindert, Philip R. Gehrman, Jennifer Ramautar, Diego R. Mazzotti, Séverine Sabia, Michael N. Weedon, Eus J. W. van Someren, Lars Ridder, Jian Wang, Vincent T. van Hees

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Genetic determinants of daytime napping and effects on cardiometabolic health av Hassan S. Dashti, Iyas Daghlas, Jacqueline M. Lane, Yunru Huang, Miriam S. Udler, Heming Wang, Hanna M. Ollila, Samuel E. Jones, Jaegil Kim, Andrew R. Wood, 23andMe Research Team, Michael N. Weedon, Stella Aslibekyan, Marta Garaulet, Richa Saxena

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Common variants show predicted polygenic effects on height in the tails of the distribution, except in extremely short individuals. av Yingleong Chan, Oddgeir L Holmen, Andrew Dauber, Lars Vatten, Aki S Havulinna, Frank Skorpen, Kirsti Kvaløy, Kaisa Silander, Thutrang T Nguyen, Cristen Willer, Michael Boehnke, Markus Perola, Aarno Palotie, Veikko Salomaa, Kristian Hveem, Timothy M Frayling, Joel N Hirschhorn, Michael N Weedon

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Imputation of variants from the 1000 Genomes Project modestly improves known associations and can identify low-frequency variant-phenotype associations undetected by HapMap based i... av Andrew R Wood, John R B Perry, Toshiko Tanaka, Dena G Hernandez, Hou-Feng Zheng, David Melzer, J Raphael Gibbs, Michael A Nalls, Michael N Weedon, Tim D Spector, J Brent Richards, Stefania Bandinelli, Luigi Ferrucci, Andrew B Singleton, Timothy M Frayling

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Heterozygous RFX6 protein truncating variants are associated with MODY with reduced penetrance av Kashyap A. Patel, Jarno Kettunen, Markku Laakso, Alena Stančáková, Thomas W. Laver, Kevin Colclough, Matthew B. Johnson, Marc Abramowicz, Leif Groop, Päivi J. Miettinen, Maggie H. Shepherd, Sarah E. Flanagan, Sian Ellard, Nobuya Inagaki, Andrew T. Hattersley, Tiinamaija Tuomi, Miriam Cnop, Michael N. Weedon

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Investigating misclassification of type 1 diabetes in a population-based cohort of British Pakistanis and Bangladeshis using polygenic risk scores av Timing Liu, Alagu Sankareswaran, Gordon Paterson, Genes & Health Research Team, Diane P. Fraser, Sam Hodgson, Qin Qin Huang, Teng Hiang Heng, Meera Ladwa, Nick Thomas, David A. van Heel, Michael N. Weedon, Chittaranjan S. Yajnik, Richard A. Oram, Giriraj R. Chandak, Hilary C. Martin, Sarah Finer

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The impact of Mendelian sleep and circadian genetic variants in a population setting. av Michael N Weedon, Samuel E Jones, Jacqueline M Lane, Jiwon Lee, Hanna M Ollila, Amy Dawes, Jess Tyrrell, Robin N Beaumont, Timo Partonen, Ilona Merikanto, Stephen S Rich, Jerome I Rotter, Timothy M Frayling, Martin K Rutter, Susan Redline, Tamar Sofer, Richa Saxena, Andrew R Wood

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Applying a genetic risk score model to enhance prediction of future multiple sclerosis diagnosis at first presentation with optic neuritis av Pavel Loginovic, Feiyi Wang, Jiang Li, Lauric Ferrat, Uyenlinh L. Mirshahi, H. Shanker Rao, Axel Petzold, Jessica Tyrrell, Harry D. Green, Michael N. Weedon, Andrea Ganna, Tiinamaija Tuomi, David J. Carey, UKBB Eye & Vision Consortium, FinnGen, Geisinger-Regeneron DiscovEHR Collaboration, Richard A. Oram, Tasanee Braithwaite

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Red blood cell distribution width: Genetic evidence for aging pathways in 116,666 volunteers. av Luke C Pilling, Janice L Atkins, Michael O Duff, Robin N Beaumont, Samuel E Jones, Jessica Tyrrell, Chia-Ling Kuo, Katherine S Ruth, Marcus A Tuke, Hanieh Yaghootkar, Andrew R Wood, Anna Murray, Michael N Weedon, Lorna W Harries, George A Kuchel, Luigi Ferrucci, Timothy M Frayling, David Melzer

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Refinement of the critical genomic region for congenital hyperinsulinism in the Chromosome 9p deletion syndrome [version 2; peer review: 2 approved, 1 approved with reservations] av Indraneel Banerjee, Senthil Senniappan, Thomas W. Laver, Richard Caswell, Martin Zenker, Klaus Mohnike, Tim Cheetham, Matthew N. Wakeling, Dunia Ismail, Belinda Lennerz, Miranda Splitt, Merih Berberoğlu, Susann Empting, Martin Wabitsch, Simone Pötzsch, Pratik Shah, Zeynep Siklar, Charles F. Verge, Michael N. Weedon, Sian Ellard, Khalid Hussain, Sarah E. Flanagan

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