Connecting Sarcomere Protein Mutations to Pathogenesis in Cardiomyopathies: The Development of ‘Disease in a Dish’ Models by Rebecca Zaunbrecher, Michael Regnier

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Elastic energy storage and radial forces in the myofilament lattice depend on sarcomere length. by C David Williams, Michael Regnier, Thomas L Daniel

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Axial and radial forces of cross-bridges depend on lattice spacing. by C David Williams, Michael Regnier, Thomas L Daniel

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Sarcomere lattice geometry influences cooperative myosin binding in muscle. by Bertrand C W Tanner, Thomas L Daniel, Michael Regnier

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Filament compliance influences cooperative activation of thin filaments and the dynamics of force production in skeletal muscle. by Bertrand C W Tanner, Thomas L Daniel, Michael Regnier

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Simvastatin provides long‐term improvement of left ventricular function and prevents cardiac fibrosis in muscular dystrophy by Min J. Kim, Kenneth L. Bible, Michael Regnier, Marvin E. Adams, Stanley C. Froehner, Nicholas P. Whitehead

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Efficacy and muscle safety assessment of fukutin-related protein gene therapy by Halli Benasutti, Joseph W. Maricelli, Jane Seto, John Hall, Christine Halbert, Jacqueline Wicki, Lydia Heusgen, Nicholas Purvis, Michael Regnier, David C. Lin, Buel D. Rodgers, Jeffrey S. Chamberlain

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Modulating the tension-time integral of the cardiac twitch prevents dilated cardiomyopathy in murine hearts by Joseph D. Powers, Kristina B. Kooiker, Allison B. Mason, Abigail E. Teitgen, Galina V. Flint, Jil C. Tardiff, Steven D. Schwartz, Andrew D. McCulloch, Michael Regnier, Jennifer Davis, Farid Moussavi-Harami

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Gene Therapy Rescues Cardiac Dysfunction in Duchenne Muscular Dystrophy Mice by Elevating Cardiomyocyte Deoxy-Adenosine Triphosphate by Stephen C. Kolwicz, Jr., PhD, John K. Hall, PhD, Farid Moussavi-Harami, MD, Xiolan Chen, PhD, Stephen D. Hauschka, PhD, Jeffrey S. Chamberlain, PhD, Michael Regnier, PhD, Guy L. Odom, PhD

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Sarcomere function activates a p53-dependent DNA damage response that promotes polyploidization and limits in vivo cell engraftment by Anthony M. Pettinato, Dasom Yoo, Jennifer VanOudenhove, Yu-Sheng Chen, Rachel Cohn, Feria A. Ladha, Xiulan Yang, Ketan Thakar, Robert Romano, Nicolas Legere, Emily Meredith, Paul Robson, Michael Regnier, Justin L. Cotney, Charles E. Murry, J. Travis Hinson

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Post-translational modification patterns on β-myosin heavy chain are altered in ischemic and nonischemic human hearts by Maicon Landim-Vieira, Matthew C Childers, Amanda L Wacker, Michelle Rodriquez Garcia, Huan He, Rakesh Singh, Elizabeth A Brundage, Jamie R Johnston, Bryan A Whitson, P Bryant Chase, Paul ML Janssen, Michael Regnier, Brandon J Biesiadecki, J Renato Pinto, Michelle S Parvatiyar

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Isolation and Mechanical Measurements of Myofibrils from Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes by Josè Manuel Pioner, Alice W. Racca, Jordan M. Klaiman, Kai-Chun Yang, Xuan Guan, Lil Pabon, Veronica Muskheli, Rebecca Zaunbrecher, Jesse Macadangdang, Mark Y. Jeong, David L. Mack, Martin K. Childers, Deok-Ho Kim, Chiara Tesi, Corrado Poggesi, Charles E. Murry, Michael Regnier

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Variants in ACTC1 underlie distal arthrogryposis accompanied by congenital heart defects by Jessica X. Chong, Matthew Carter Childers, Colby T. Marvin, Anthony J. Marcello, Hernan Gonorazky, Lili-Naz Hazrati, James J. Dowling, Fatema Al Amrani, Yasemin Alanay, Yolanda Nieto, Miguel Á Marín Gabriel, Arthur S. Aylsworth, Kati J. Buckingham, Kathryn M. Shively, Olivia Sommers, Kailyn Anderson, Michael Regnier, Michael J. Bamshad

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Corrigendum: Calcium handling maturation and adaptation to increased substrate stiffness in human iPSC-derived cardiomyocytes: the impact of full-length dystrophin deficiency by Josè Manuel Pioner, Lorenzo Santini, Chiara Palandri, Marianna Langione, Bruno Grandinetti, Silvia Querceto, Daniele Martella, Daniele Martella, Costanza Mazzantini, Beatrice Scellini, Lucrezia Giammarino, Flavia Lupi, Francesco Mazzarotto, Francesco Mazzarotto, Aoife Gowran, Davide Rovina, Rosaria Santoro, Giulio Pompilio, Giulio Pompilio, Chiara Tesi, Camilla Parmeggiani, Camilla Parmeggiani, Michael Regnier, Elisabetta Cerbai, David L. Mack, Corrado Poggesi, Cecilia Ferrantini, Raffaele Coppini

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Calcium handling maturation and adaptation to increased substrate stiffness in human iPSC-derived cardiomyocytes: The impact of full-length dystrophin deficiency by Josè Manuel Pioner, Lorenzo Santini, Chiara Palandri, Marianna Langione, Bruno Grandinetti, Silvia Querceto, Daniele Martella, Daniele Martella, Costanza Mazzantini, Beatrice Scellini, Lucrezia Giammarino, Flavia Lupi, Francesco Mazzarotto, Francesco Mazzarotto, Aoife Gowran, Davide Rovina, Rosaria Santoro, Giulio Pompilio, Giulio Pompilio, Chiara Tesi, Camilla Parmeggiani, Camilla Parmeggiani, Michael Regnier, Elisabetta Cerbai, David L. Mack, Corrado Poggesi, Cecilia Ferrantini, Raffaele Coppini

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Novel Adult-Onset Systolic Cardiomyopathy Due to MYH7 E848G Mutation in Patient-Derived Induced Pluripotent Stem Cells by Kai-Chun Yang, MD, Astrid Breitbart, MD, Willem J. De Lange, PhD, Peter Hofsteen, PhD, Akiko Futakuchi-Tsuchida, BS, Joy Xu, MSE, Cody Schopf, BS, Maria V. Razumova, PhD, Alex Jiao, PhD, Robert Boucek, MD, Lil Pabon, PhD, Hans Reinecke, PhD, Deok-Ho Kim, PhD, J. Carter Ralphe, MD, Michael Regnier, PhD, Charles E. Murry, MD, PhD

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