Michael Thorpe

Michael Thorpe (born March 12, 1944) is an English-American physicist and Foundation Professor of Physics at Arizona State University. He received his D. Phil from Oxford University in 1968 in condensed matter physics under supervision of Sir Roger James Elliott. His early research was on network glasses, but has recently focused on applying his knowledge to the study of protein dynamics.

In 2003, Thorpe joined Arizona State University from Michigan State University. His research interests are in the theory of disordered systems, with a special emphasis on properties that are determined by geometry and topology. He has a research background in condensed matter theory, and in recent years has developed the mathematical theory of flexibility and mobility for use in network glasses. Provided by Wikipedia
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  1. 1
    rMCP-2, the Major Rat Mucosal Mast Cell Protease, an Analysis of Its Extended Cleavage Specificity and Its Potential Role in Regulating Intestinal Permeability by the Cleavage of Cell Adhesion and Junction Proteins.

    rMCP-2, the Major Rat Mucosal Mast Cell Protease, an Analysis of Its Extended Cleavage Specificity and Its Potential Role in Regulating Intestinal Permeability by the Cleavage of C... by Zhirong Fu, Michael Thorpe, Lars Hellman

    Published 2015-01-01
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  2. 2
    The Importance of Exosite Interactions for Substrate Cleavage by Human Thrombin.

    The Importance of Exosite Interactions for Substrate Cleavage by Human Thrombin. by Gurdeep Chahal, Michael Thorpe, Lars Hellman

    Published 2015-01-01
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  3. 3
    The Extended Cleavage Specificity of Channel Catfish Granzyme-like II, A Highly Specific Elastase, Expressed by Natural Killer-like Cells

    The Extended Cleavage Specificity of Channel Catfish Granzyme-like II, A Highly Specific Elastase, Expressed by Natural Killer-like Cells by Michael Thorpe, Srinivas Akula, Zhirong Fu, Lars Hellman

    Published 2023-12-01
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  4. 4
    Asp-ase Activity of the Opossum Granzyme B Supports the Role of Granzyme B as Part of Anti-Viral Immunity Already during Early Mammalian Evolution.

    Asp-ase Activity of the Opossum Granzyme B Supports the Role of Granzyme B as Part of Anti-Viral Immunity Already during Early Mammalian Evolution. by Zhirong Fu, Michael Thorpe, Srinivas Akula, Lars Hellman

    Published 2016-01-01
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  5. 5
    Potent and Broad but not Unselective Cleavage of Cytokines and Chemokines by Human Neutrophil Elastase and Proteinase 3

    Potent and Broad but not Unselective Cleavage of Cytokines and Chemokines by Human Neutrophil Elastase and Proteinase 3 by Zhirong Fu, Srinivas Akula, Michael Thorpe, Lars Hellman

    Published 2020-01-01
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  6. 6
    The extended cleavage specificity of human thrombin.

    The extended cleavage specificity of human thrombin. by Maike Gallwitz, Mattias Enoksson, Michael Thorpe, Lars Hellman

    Published 2012-01-01
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  7. 7
    Granule Associated Serine Proteases of Hematopoietic Cells - An Analysis of Their Appearance and Diversification during Vertebrate Evolution.

    Granule Associated Serine Proteases of Hematopoietic Cells - An Analysis of Their Appearance and Diversification during Vertebrate Evolution. by Srinivas Akula, Michael Thorpe, Vamsi Boinapally, Lars Hellman

    Published 2015-01-01
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  8. 8
    Correction: Granule Associated Serine Proteases of Hematopoietic Cells - An Analysis of Their Appearance and Diversification during Vertebrate Evolution.

    Correction: Granule Associated Serine Proteases of Hematopoietic Cells - An Analysis of Their Appearance and Diversification during Vertebrate Evolution. by Srinivas Akula, Michael Thorpe, Vamsi Boinapally, Lars Hellman

    Published 2015-01-01
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  9. 9
    Tracing the Origins of IgE, Mast Cells, and Allergies by Studies of Wild Animals

    Tracing the Origins of IgE, Mast Cells, and Allergies by Studies of Wild Animals by Lars Torkel Hellman, Srinivas Akula, Michael Thorpe, Zhirong Fu

    Published 2017-12-01
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  10. 10
    Extended Cleavage Specificity of the Rat Vascular Chymase, a Potential Blood Pressure Regulating Enzyme Expressed by Rat Vascular Smooth Muscle Cells

    Extended Cleavage Specificity of the Rat Vascular Chymase, a Potential Blood Pressure Regulating Enzyme Expressed by Rat Vascular Smooth Muscle Cells by Petter Berglund, Srinivas Akula, Zhirong Fu, Michael Thorpe, Lars Hellman

    Published 2020-11-01
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  11. 11
    Extended Cleavage Specificity of Human Neutrophil Elastase, Human Proteinase 3, and Their Distant Ortholog Clawed Frog PR3—Three Elastases With Similar Primary but Different Extended Specificities and Stability

    Extended Cleavage Specificity of Human Neutrophil Elastase, Human Proteinase 3, and Their Distant Ortholog Clawed Frog PR3—Three Elastases With Similar Primary but Different Extend... by Zhirong Fu, Michael Thorpe, Srinivas Akula, Gurdeep Chahal, Lars T. Hellman

    Published 2018-10-01
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  12. 12
    How Relevant Are Bone Marrow-Derived Mast Cells (BMMCs) as Models for Tissue Mast Cells? A Comparative Transcriptome Analysis of BMMCs and Peritoneal Mast Cells

    How Relevant Are Bone Marrow-Derived Mast Cells (BMMCs) as Models for Tissue Mast Cells? A Comparative Transcriptome Analysis of BMMCs and Peritoneal Mast Cells by Srinivas Akula, Aida Paivandy, Zhirong Fu, Michael Thorpe, Gunnar Pejler, Lars Hellman

    Published 2020-09-01
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  13. 13
    Mutations in Arg143 and Lys192 of the Human Mast Cell Chymase Markedly Affect the Activity of Five Potent Human Chymase Inhibitors.

    Mutations in Arg143 and Lys192 of the Human Mast Cell Chymase Markedly Affect the Activity of Five Potent Human Chymase Inhibitors. by Parvin Ahooghalandari, Nina Hanke, Michael Thorpe, Andreas Witte, Josef Messinger, Lars Hellman

    Published 2013-01-01
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  14. 14
    Quantitative In-Depth Analysis of the Mouse Mast Cell Transcriptome Reveals Organ-Specific Mast Cell Heterogeneity

    Quantitative In-Depth Analysis of the Mouse Mast Cell Transcriptome Reveals Organ-Specific Mast Cell Heterogeneity by Srinivas Akula, Aida Paivandy, Zhirong Fu, Michael Thorpe, Gunnar Pejler, Lars Hellman

    Published 2020-01-01
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  15. 15
    Extended cleavage specificity of human neutrophil cathepsin G: A low activity protease with dual chymase and tryptase-type specificities.

    Extended cleavage specificity of human neutrophil cathepsin G: A low activity protease with dual chymase and tryptase-type specificities. by Michael Thorpe, Zhirong Fu, Gurdeep Chahal, Srinivas Akula, Jukka Kervinen, Lawrence de Garavilla, Lars Hellman

    Published 2018-01-01
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  16. 16
    Extended cleavage specificities of mast cell proteases 1 and 2 from golden hamster: Classical chymase and an elastolytic protease comparable to rat and mouse MCP-5.

    Extended cleavage specificities of mast cell proteases 1 and 2 from golden hamster: Classical chymase and an elastolytic protease comparable to rat and mouse MCP-5. by Michael Thorpe, Zhirong Fu, Emanuelle Albat, Srinivas Akula, Lawrence de Garavilla, Jukka Kervinen, Lars Hellman

    Published 2018-01-01
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  17. 17
    Extended Cleavage Specificity of two Hematopoietic Serine Proteases from a Ray-Finned Fish, the Spotted Gar (<i>Lepisosteus oculatus</i>)

    Extended Cleavage Specificity of two Hematopoietic Serine Proteases from a Ray-Finned Fish, the Spotted Gar (<i>Lepisosteus oculatus</i>) by Paolo Valentini, Srinivas Akula, Abigail Alvarado-Vazquez, Jenny Hallgren, Zhirong Fu, Brett Racicot, Ingo Braasch, Michael Thorpe, Lars Hellman

    Published 2024-01-01
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  18. 18
    Manganese-Iron Phosphate Nodules at the Groken Site, Gale Crater, Mars

    Manganese-Iron Phosphate Nodules at the Groken Site, Gale Crater, Mars by Allan H. Treiman, Nina L. Lanza, Scott VanBommel, Jeff Berger, Roger Wiens, Thomas Bristow, Jeffrey Johnson, Melissa Rice, Reginald Hart, Amy McAdam, Patrick Gasda, Pierre-Yves Meslin, Albert Yen, Amy J. Williams, Ashwin Vasavada, David Vaniman, Valerie Tu, Michael Thorpe, Elizabeth D. Swanner, Christina Seeger, Susanne P. Schwenzer, Susanne Schröder, Elizabeth Rampe, William Rapin, Silas J. Ralston, Tanya Peretyazhko, Horton Newsom, Richard V. Morris, Douglas Ming, Matteo Loche, Stéphane Le Mouélic, Christopher House, Robert Hazen, John P. Grotzinger, Ralf Gellert, Olivier Gasnault, Woodward W. Fischer, Ari Essunfeld, Robert T. Downs, Gordon W. Downs, Erwin Dehouck, Laura J. Crossey, Agnes Cousin, Jade M. Comellas, Joanna V. Clark, Benton Clark, Steve Chipera, Gwenaël Caravaca, John Bridges, David F. Blake, Ryan Anderson

    Published 2023-08-01
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