Fatal Lactic Acidosis in a Kidney Transplant Recipient on Combination Antiretroviral Therapy after Initiation of Tacrolimus Therapy by Michael V. Holmes, Ranjababu Kulasegaram, Sebastian B. Lucas, Terry Wong, Rachel Hilton

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Constructing an atlas of associations between polygenic scores from across the human phenome and circulating metabolic biomarkers by Si Fang, Michael V Holmes, Tom R Gaunt, George Davey Smith, Tom G Richardson

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A genome-wide association study of childhood adiposity and blood lipids [version 2; peer review: 1 approved, 2 approved with reservations] by George Davey Smith, Eleanor Sanderson, Katie O'Nunain, Tom G Richardson, Michael V Holmes

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Genomic Research to Identify Novel Pathways in the Development of Abdominal Aortic Aneurysm by Seamus C. Harrison, Anastasia Z. Kalea, Michael V. Holmes, Obi Agu, Steve E. Humphries

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Paradoxical association of C-reactive protein with endothelial function in rheumatoid arthritis. by Michael V Holmes, Benyu Jiang, Karen McNeill, Melinda Wong, Stephen P Oakley, Bruce Kirkham, Phil J Chowienczyk

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Characterising metabolomic signatures of lipid-modifying therapies through drug target mendelian randomisation. by Tom G Richardson, Genevieve M Leyden, Qin Wang, Joshua A Bell, Benjamin Elsworth, George Davey Smith, Michael V Holmes

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Distinct metabolic features of genetic liability to type 2 diabetes and coronary artery disease: a reverse Mendelian randomization studyResearch in context by Madeleine L. Smith, Caroline J. Bull, Michael V. Holmes, George Davey Smith, Eleanor Sanderson, Emma L. Anderson, Joshua A. Bell

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Visceral adiposity is associated with metabolic profiles predictive of type 2 diabetes and myocardial infarction by Javeria Raheem, Eeva Sliz, Jean Shin, Michael V. Holmes, G. Bruce Pike, Louis Richer, Daniel Gaudet, Tomas Paus, Zdenka Pausova

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NMR Metabolite Profiles in Male Meat-Eaters, Fish-Eaters, Vegetarians and Vegans, and Comparison with MS Metabolite Profiles by Julie A. Schmidt, Georgina K. Fensom, Sabina Rinaldi, Augustin Scalbert, Marc J. Gunter, Michael V. Holmes, Timothy J. Key, Ruth C. Travis

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Metabolic Biomarker Discovery for Risk of Peripheral Artery Disease Compared With Coronary Artery Disease: Lipoprotein and Metabolite Profiling of 31 657 Individuals From 5 Prospec... by Emmi Tikkanen, Vilma Jägerroos, Michael V. Holmes, Naveed Sattar, Mika Ala‐Korpela, Pekka Jousilahti, Annamari Lundqvist, Markus Perola, Veikko Salomaa, Peter Würtz

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Causal relationships between obesity and the leading causes of death in women and men. by Jenny C Censin, Sanne A E Peters, Jonas Bovijn, Teresa Ferreira, Sara L Pulit, Reedik Mägi, Anubha Mahajan, Michael V Holmes, Cecilia M Lindgren

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Obesity and risk of female reproductive conditions: A Mendelian randomisation study. by Samvida S Venkatesh, Teresa Ferreira, Stefania Benonisdottir, Nilufer Rahmioglu, Christian M Becker, Ingrid Granne, Krina T Zondervan, Michael V Holmes, Cecilia M Lindgren, Laura B L Wittemans

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Correction: Obesity and risk of female reproductive conditions: A Mendelian randomisation study. by Samvida S Venkatesh, Teresa Ferreira, Stefania Benonisdottir, Nilufer Rahmioglu, Christian M Becker, Ingrid Granne, Krina T Zondervan, Michael V Holmes, Cecilia M Lindgren, Laura B L Wittemans

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Longitudinal trajectories of blood lipid levels in an ageing population sample of Russian Western-Siberian urban population. by Jaroslav A Hubacek, Yuri Nikitin, Yulia Ragino, Ekaterina Stakhneva, Hynek Pikhart, Anne Peasey, Michael V Holmes, Denes Stefler, Andrey Ryabikov, Eugeny Verevkin, Martin Bobak, Sofia Malyutina

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Oral and gut microbiome profiles in people with early idiopathic Parkinson’s disease by Keaton Stagaman, Matthew J. Kmiecik, Madeleine Wetzel, Stella Aslibekyan, Teresa Filshtein Sonmez, Pierre Fontanillas, 23andMe Research Team, Joyce Tung, Michael V. Holmes, Seth T. Walk, Madelyn C. Houser, Lucy Norcliffe-Kaufmann

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Effects of general and central adiposity on circulating lipoprotein, lipid, and metabolite levels in UK Biobank: A multivariable Mendelian randomization study by Joshua A. Bell, Tom G. Richardson, Qin Wang, Eleanor Sanderson, Tom Palmer, Venexia Walker, Linda M. O'Keeffe, Nicholas J. Timpson, Anna Cichonska, Heli Julkunen, Peter Würtz, Michael V. Holmes, George Davey Smith

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Metabolic and lifestyle risk factors for acute pancreatitis in Chinese adults: A prospective cohort study of 0.5 million people. by Yuanjie Pang, Christiana Kartsonaki, Iain Turnbull, Yu Guo, Ling Yang, Zheng Bian, Yiping Chen, Iona Y Millwood, Fiona Bragg, Weiwei Gong, Qinai Xu, Quan Kang, Junshi Chen, Liming Li, Michael V Holmes, Zhengming Chen

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Guidelines for performing Mendelian randomization investigations: update for summer 2023 [version 3; peer review: 2 approved] by Frank Dudbridge, Caroline L. Relton, George Davey Smith, Jean V. Morrison, Zoltán Kutalik, Stephen Burgess, Wei Pan, Dipender Gill, Neil M. Davies, Fernando P. Hartwig, M. Maria Glymour, Cosetta Minelli, Michael V. Holmes, Evropi Theodoratou

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Association of vitamin D with risk of type 2 diabetes: A Mendelian randomisation study in European and Chinese adults. by Ling Lu, Derrick A Bennett, Iona Y Millwood, Sarah Parish, Mark I McCarthy, Anubha Mahajan, Xu Lin, Fiona Bragg, Yu Guo, Michael V Holmes, Shoaib Afzal, Børge G Nordestgaard, Zheng Bian, Michael Hill, Robin G Walters, Liming Li, Zhengming Chen, Robert Clarke

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Efficacy of metformin targets on cardiometabolic health in the general population and non-diabetic individuals: a Mendelian randomization studyResearch in context by Jie Zheng, Min Xu, Qian Yang, Chunyan Hu, Venexia Walker, Jieli Lu, Jiqiu Wang, Ruixin Liu, Yu Xu, Tiange Wang, Zhiyun Zhao, Jinqiu Yuan, Stephen Burgess, Shiu Lun Au Yeung, Shan Luo, Emma L. Anderson, Michael V. Holmes, George Davey Smith, Guang Ning, Weiqing Wang, Tom R. Gaunt, Yufang Bi

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