PI-07: THE INTERNATIONAL HEMOGLOBINOPATHY RESEARCH NETWORK (INHERENT): AN INTERNATIONAL INITIATVE TO STUDY THE ROLE OF GENETIC MODIFIERS IN HEMOGLOBINOPATHIES by KOUNTOURIS P., STEPHANOU C., ARCHER N., BONIFAZI F., GIANNUZZI V., KUO K., MAGGIO A., MAKANI J., MAÑÚ PEREIRA M., MICHAILIDOU K., NKYA S., NNODU O., TROMPETER S., TSHILOLO L., WONKAM A., ZILFALIL B., INUSA B., KLEANTHOUS M.

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A meta-analysis of genome-wide association studies of breast cancer identifies two novel susceptibility loci at 6q14 and 20q11. by Siddiq, A, Couch, F, Chen, G, Lindström, S, Eccles, D, Millikan, R, Michailidou, K, Stram, DO, Beckmann, L, Rhie, S, Ambrosone, C, Aittomäki, K, Amiano, P, Apicella, C, Baglietto, L, Bandera, E, Beckmann, M, Berg, C, Bernstein, L, Blomqvist, C, Brauch, H, Brinton, L, Bui, Q, Buring, J, Buys, S

Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer. by Bojesen, SE, Pooley, K, Johnatty, SE, Beesley, J, Michailidou, K, Tyrer, J, Edwards, S, Pickett, H, Shen, H, Smart, C, Hillman, K, Mai, P, Lawrenson, K, Stutz, MD, Lu, Y, Karevan, R, Woods, N, Johnston, R, French, J, Chen, X, Weischer, M, Nielsen, S, Maranian, M, Ghoussaini, M, Ahmed, S

Functional variants at the 11q13 risk locus for breast cancer regulate cyclin D1 expression through long-range enhancers. by French, J, Ghoussaini, M, Edwards, S, Meyer, K, Michailidou, K, Ahmed, S, Khan, S, Maranian, M, O'Reilly, M, Hillman, K, Betts, J, Carroll, T, Bailey, P, Dicks, E, Beesley, J, Tyrer, J, Maia, A, Beck, A, Knoblauch, N, Chen, C, Kraft, P, Barnes, D, González-Neira, A, Alonso, MR, Herrero, D

Functional variants at the 11q13 risk locus for breast cancer regulate cyclin D1 expression through long-range enhancers by French, J, Ghoussaini, M, Edwards, S, Meyer, K, Michailidou, K, Ahmed, S, Khan, S, Maranian, M, O'Reilly, M, Hillman, K, Betts, J, Carroll, T, Bailey, P, Dicks, E, Beesley, J, Tyrer, J, Maia, A, Beck, A, Knoblauch, N, Chen, C, Kraft, P, Kraft, P, Barnes, D, González-Neira, A, Alonso, MR

Lessons learned from a candidate gene study investigating aromatase inhibitor treatment outcome in breast cancer by Hoppe, R, Winter, S, Lo, W, Michailidou, K, Bolla, MK, Keeman, R, Wang, Q, Dennis, J, Lush, M, Kalari, KR, Goetz, MP, Wang, L, Cairns, J, Weinshilboum, R, Shepherd, L, Chen, BE, Häberle, L, Ruebner, M, Beckmann, MW, He, W, Larson, NL, Armasu, SM, Schroth, W, Chowbay, B, Tomlinson, I

Genome-wide association studies identify four ER negative-specific breast cancer risk loci. by Garcia-Closas, M, Couch, F, Lindstrom, S, Michailidou, K, Schmidt, M, Brook, M, Orr, N, Rhie, S, Riboli, E, Feigelson, H, Le Marchand, L, Buring, J, Eccles, D, Miron, P, Fasching, P, Brauch, H, Chang-Claude, J, Carpenter, J, Godwin, A, Nevanlinna, H, Giles, G, Cox, A, Hopper, J, Bolla, M, Wang, Q

FGF receptor genes and breast cancer susceptibility: results from the Breast Cancer Association Consortium. by Agarwal, D, Pineda, S, Michailidou, K, Herranz, J, Pita, G, Moreno, LT, Alonso, MR, Dennis, J, Wang, Q, Bolla, M, Meyer, K, Menéndez-Rodríguez, P, Hardisson, D, Mendiola, M, González-Neira, A, Lindblom, A, Margolin, S, Swerdlow, A, Ashworth, A, Orr, N, Jones, M, Matsuo, K, Ito, H, Iwata, H, Kondo, N

Fine-scale mapping of the FGFR2 breast cancer risk locus: Putative functional variants differentially bind FOXA1 and E2F1 by Meyer, K, O'Reilly, M, Michailidou, K, Carlebur, S, Edwards, S, Edwards, S, French, J, French, J, Prathalingham, R, Dennis, J, Bolla, M, Wang, Q, De Santiago, I, Hopper, J, Tsimiklis, H, Apicella, C, Southey, M, Schmidt, M, Broeks, A, Van 't Veer, L, Hogervorst, F, Muir, K, Muir, K, Lophatananon, A, Stewart-Brown, S

Fine-scale mapping of the FGFR2 breast cancer risk locus: putative functional variants differentially bind FOXA1 and E2F1. by Meyer, K, O'Reilly, M, Michailidou, K, Carlebur, S, Edwards, S, French, J, Prathalingham, R, Dennis, J, Bolla, M, Wang, Q, de Santiago, I, Hopper, J, Tsimiklis, H, Apicella, C, Southey, M, Schmidt, M, Broeks, A, Van 't Veer, L, Hogervorst, F, Muir, K, Lophatananon, A, Stewart-Brown, S, Siriwanarangsan, P, Fasching, P, Lux, M

Genetic variation in mitotic regulatory pathway genes is associated with breast tumor grade. by Purrington, K, Slettedahl, S, Bolla, M, Michailidou, K, Czene, K, Nevanlinna, H, Bojesen, SE, Andrulis, I, Cox, A, Hall, P, Carpenter, J, Yannoukakos, D, Haiman, C, Fasching, P, Mannermaa, A, Winqvist, R, Brenner, H, Lindblom, A, Chenevix-Trench, G, Benitez, J, Swerdlow, A, Kristensen, V, Guénel, P, Meindl, A, Darabi, H

A large-scale assessment of two-way SNP interactions in breast cancer susceptibility using 46,450 cases and 42,461 controls from the breast cancer association consortium. by Milne, R, Herranz, J, Michailidou, K, Dennis, J, Tyrer, J, Zamora, M, Arias-Perez, J, González-Neira, A, Pita, G, Alonso, MR, Wang, Q, Bolla, M, Czene, K, Eriksson, M, Humphreys, K, Darabi, H, Li, J, Anton-Culver, H, Neuhausen, S, Ziogas, A, Clarke, C, Hopper, J, Dite, G, Apicella, C, Southey, M

Genome-wide association analysis identifies three new breast cancer susceptibility loci. by Ghoussaini, M, Fletcher, O, Michailidou, K, Turnbull, C, Schmidt, M, Dicks, E, Dennis, J, Wang, Q, Humphreys, M, Luccarini, C, Baynes, C, Conroy, D, Maranian, M, Ahmed, S, Driver, K, Johnson, N, Orr, N, dos Santos Silva, I, Waisfisz, Q, Meijers-Heijboer, H, Uitterlinden, A, Rivadeneira, F, Hall, P, Czene, K, Irwanto, A

Large-scale genotyping identifies 41 new loci associated with breast cancer risk. by Michailidou, K, Hall, P, Gonzalez-Neira, A, Ghoussaini, M, Dennis, J, Milne, R, Schmidt, M, Chang-Claude, J, Bojesen, SE, Bolla, M, Wang, Q, Dicks, E, Lee, A, Turnbull, C, Rahman, N, Fletcher, O, Peto, J, Gibson, L, Dos Santos Silva, I, Nevanlinna, H, Muranen, T, Aittomäki, K, Blomqvist, C, Czene, K, Irwanto, A

Common non-synonymous SNPs associated with breast cancer susceptibility: findings from the Breast Cancer Association Consortium. by Milne, R, Burwinkel, B, Michailidou, K, Arias-Perez, J, Zamora, M, Menéndez-Rodríguez, P, Hardisson, D, Mendiola, M, González-Neira, A, Pita, G, Alonso, MR, Dennis, J, Wang, Q, Bolla, M, Swerdlow, A, Ashworth, A, Orr, N, Schoemaker, M, Ko, Y, Brauch, H, Hamann, U, Andrulis, I, Knight, J, Glendon, G, Tchatchou, S

Genome-wide association analysis identifies three new breast cancer susceptibility loci by Ghoussaini, M, Fletcher, O, Michailidou, K, Turnbull, C, Schmidt, M, Dicks, E, Dennis, J, Wang, Q, Humphreys, M, Luccarini, C, Baynes, C, Conroy, D, Maranian, M, Ahmed, S, Driver, K, Johnson, N, Orr, N, Dos Santos Silva, I, Waisfisz, Q, Meijers-Heijboer, H, Uitterlinden, A, Rivadeneira, F, Hall, P, Czene, K, Irwanto, A

Genome-wide association analysis identifies three new breast cancer susceptibility loci by Ghoussaini, M, Fletcher, O, Michailidou, K, Turnbull, C, Schmidt, M, Schmidt, M, Dicks, E, Dennis, J, Wang, Q, Humphreys, M, Luccarini, C, Baynes, C, Conroy, D, Maranian, M, Ahmed, S, Driver, K, Johnson, N, Orr, N, Dos Santos Silva, I, Waisfisz, Q, Meijers-Heijboer, H, Uitterlinden, A, Rivadeneira, F, Rivadeneira, F, Hall, P

Identification and characterization of novel associations in the CASP8/ALS2CR12 region on chromosome 2 with breast cancer risk. by Lin, W, Camp, N, Ghoussaini, M, Beesley, J, Michailidou, K, Hopper, J, Apicella, C, Southey, M, Stone, J, Schmidt, M, Broeks, A, Van't Veer, L, Th Rutgers, E, Muir, K, Lophatananon, A, Stewart-Brown, S, Siriwanarangsan, P, Fasching, P, Haeberle, L, Ekici, AB, Beckmann, M, Peto, J, Dos-Santos-Silva, I, Fletcher, O, Johnson, N

Physical activity, sedentary time and breast cancer risk: a Mendelian randomisation study by Dixon-Suen, SC, Lewis, SJ, Martin, RM, English, DR, Boyle, T, Giles, GG, Michailidou, K, Bolla, MK, Wang, Q, Dennis, J, Lush, M, Ahearn, TU, Ambrosone, CB, Andrulis, IL, Anton-Culver, H, Arndt, V, Aronson, KJ, Augustinsson, A, Auvinen, P, Beane Freeman, LE, Becher, H, Beckmann, MW, Behrens, S, Bermisheva, M, Blomqvist, C, Bogdanova, NV, Bojesen, SE, Bonanni, B, Brenner, H, Brüning, T, Buys, SS, Camp, NJ, Campa, D, Canzian, F, Castelao, JE, Cessna, MH, Chang-Claude, J, Chanock, SJ, Clarke, CL, Conroy, DM, Couch, FJ, Cox, A, Cross, SS, Czene, K, Daly, MB, Devilee, P, Dörk, T, Dwek, M, Eccles, DM, Hunter, DJ

Aggregation tests identify new gene associations with breast cancer in populations with diverse ancestry by Mueller, SH, Lai, AG, Valkovskaya, M, Michailidou, K, Bolla, MK, Wang, Q, Dennis, J, Lush, M, Abu-Ful, Z, Ahearn, TU, Andrulis, IL, Anton-Culver, H, Antonenkova, NN, Arndt, V, Aronson, KJ, Augustinsson, A, Baert, T, Freeman, LEB, Beckmann, MW, Behrens, S, Benitez, J, Bermisheva, M, Blomqvist, C, Bogdanova, NV, Bojesen, SE, Bonanni, B, Brenner, H, Brucker, SY, Buys, SS, Castelao, JE, Chan, TL, Chang-Claude, J, Chanock, SJ, Choi, J-Y, Chung, WK, Colonna, SV, Cornelissen, S, Couch, FJ, Czene, K, Daly, MB, Devilee, P, Dörk, T, Dossus, L, Dwek, M, Eccles, DM, Ekici, AB, Eliassen, AH, Engel, C, Hunter, DJ