Stem Cell Modeling of Core Binding Factor Acute Myeloid Leukemia by Federico Mosna, Michele Gottardi

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Editorial: Inflammation and blood diseases, a dog chasing its tail by Cosimo Cumbo, Francesco Tarantini, Michele Gottardi, Francesco Albano

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2-Hydroxyglutarate in Acute Myeloid Leukemia: A Journey from Pathogenesis to Therapies by Vittoria Raimondi, Giulia Ciotti, Michele Gottardi, Francesco Ciccarese

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Spatial-transcriptomic profiling: a new lens for understanding myelofibrosis pathophysiology by Edoardo Peroni, Elisabetta Calistri, Rosario Amato, Michele Gottardi, Antonio Rosato

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CXCL12 and [N33A]CXCL12 in 5637 and HeLa cells: regulating HER1 phosphorylation via calmodulin/calcineurin. by Antonella Rigo, Michele Gottardi, Ernesto Damiani, Massimiliano Bonifacio, Isacco Ferrarini, Pierluigi Mauri, Fabrizio Vinante

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CPX-351 and allogeneic stem cell transplant for a therapy-related acute myeloid leukemia that developed after treatment of acute promyelocytic leukemia: a case report and review of... by Alessandra Sperotto, Maria Teresa Lupo Stanghellini, Jacopo Peccatori, Roberta De Marchi, Simona Piemontese, Giulia Ciotti, Marco Basso, Elisabetta Pierdomenico, Paolo Fiore, Fabio Ciceri, Michele Gottardi

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Severe hypereosinophilia in a patient treated with dupilumab and shift to mepolizumab: the importance of multidisciplinary management. A case report and literature review by Sara Munari, Giulia Ciotti, Walter Cestaro, Lorenzo Corsi, Silvia Tonin, Andrea Ballarin, Ariel Floriani, Cristina Dartora, Annamaria Bosi, Matteo Tacconi, Francesco Gialdini, Michele Gottardi, Francesco Menzella

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Measurable Residual Disease and Clonal Evolution in Acute Myeloid Leukemia from Diagnosis to Post-Transplant Follow-Up: The Role of Next-Generation Sequencing by Alessandra Sperotto, Maria Teresa Bochicchio, Giorgia Simonetti, Francesco Buccisano, Jacopo Peccatori, Simona Piemontese, Elisabetta Calistri, Giulia Ciotti, Elisabetta Pierdomenico, Roberta De Marchi, Fabio Ciceri, Michele Gottardi

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Antigen rapid diagnostic test monitoring for SARS‐CoV‐2 in asymptomatic and fully vaccinated cancer patients: Is it cost‐effective? by Mario Caccese, Anna Maria Saieva, Valentina Guarneri, Sara Lonardi, Massimo Cacco, Vanna Chiarion Sileni, Michele Gottardi, Eleonora Mioranza, Francesca Bergamo, Antonella Brunello, Vittorina Zagonel, Patrizia Benini

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Clinical and experimental efficacy of gemtuzumab ozogamicin in core binding factor acute myeloid leukemia by Michele Gottardi, Federico Mosna, Sergio De Angeli, Cristina Papayannidis, Anna Candoni, Marino Clavio, Cristina Tecchio, Andrea Piccin, Marta Campo dell’Orto, Fabio Benedetti, Giovanni Martinelli, Filippo Gherlinzoni

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Hypomethylating Agents (HMAs) as Salvage Therapy in Relapsed or Refractory AML: An Italian Multicentric Retrospective Study by Federica Lessi, Marica Laurino, Cristina Papayannidis, Orsola Vitagliano, Francesco Grimaldi, Davide Lazzarotto, Michele Gottardi, Elena Crisà, Marta Riva, Gianluigi Reda, Mario Ermani, Gianpietro Semenzato, Livio Trentin, Felicetto Ferrara

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PB1792: REPURPOSING OF ANTIBIOTICS INHIBITING MITOCHONDRIAL TRANSLATION IN COMBINATION WITH VENETOCLAX IN ACUTE MYELOID LEUKEMIA: FROM PRECLINICAL MODELS TO CLINICAL PRACTICE by Viviana Amato, Stefania Fusani, Cristina Papayannidis, Jacopo Nanni, Antonio Curti, Francesco Marchesi, Maurizio Fanciulli, Giorgia Simonetti, Gerardo Musuraca, Giovanni Marconi, Michele Gottardi, Alessandra Sperotto, Alessandra Rossi, Alessio Maria Edoardo Maraglino, Simona Sammassimo, Federica Gigli, Elisabetta Todisco, Corrado Tarella, Fabio Giglio, Enrico Derenzini

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Adrenomedullin Expression Characterizes Leukemia Stem Cells and Associates With an Inflammatory Signature in Acute Myeloid Leukemia by Giorgia Simonetti, Davide Angeli, Elisabetta Petracci, Eugenio Fonzi, Susanna Vedovato, Alessandra Sperotto, Antonella Padella, Martina Ghetti, Anna Ferrari, Valentina Robustelli, Valentina Robustelli, Rosa Di Liddo, Maria Teresa Conconi, Cristina Papayannidis, Claudio Cerchione, Michela Rondoni, Annalisa Astolfi, Annalisa Astolfi, Emanuela Ottaviani, Giovanni Martinelli, Michele Gottardi

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Exploring the role of PARP1 inhibition in enhancing antibody–drug conjugate therapy for acute leukemias: insights from DNA damage response pathway interactions by Andrea Ghelli Luserna di Rorà, Mouna Jandoubi, Antonella Padella, Anna Ferrari, Andrea Marranci, Cristina Mazzotti, Francesco Olimpico, Martina Ghetti, Lorenzo Ledda, Maria Teresa Bochicchio, Matteo Paganelli, Michele Zanoni, Alessandro Cafaro, Chiara Servili, Sara Galimberti, Michele Gottardi, Michela Rondoni, Mauro Endri, Daniela Onofrillo, Ernesta Audisio, Giovanni Marconi, Giorgia Simonetti, Giovanni Martinelli

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Long-term real-world evidence of CPX-351 of high-risk patients with AML identified high rate of negative MRD and prolonged OS by Thomas Cluzeau, Fabio Guolo, Edmond Chiche, Paola Minetto, Ramy Rahme, Sarah Bertoli, Luana Fianchi, Jean-Baptiste Micol, Michele Gottardi, Pierre Peterlin, Sara Galimberti, Xavier Thomas, Giuliana Rizzuto, Olivier Legrand, Michela Rondoni, Emmanuel Raffoux, Giambattista Bertani, Alexis Caulier, Michelina D’Argenio, Caroline Bonmati, Atto Billio, Caroline Lejeune, Barbara Scappini, Arnaud Pigneux, Patrizia Zappasodi, Christan Recher, Francesco Grimaldi, Lionel Ades, Roberto M. Lemoli

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P505: GIMEMA AML1819 TRIAL: GEMTUZUMAB OZOGAMICIN PLUS INTENSIVE CHEMOTHERAPY IMPACTS ON THE LEVEL OF POST-CONSOLIDATION MEASURABLE RESIDUAL DISEASE (MRD) IN ACUTE MYELOID LEUKEMIA by Adriano Venditti, Alfonso Piciocchi, Luca Maurillo, Maria Ilaria Del Principe, Raffaele Palmieri, Stefano Soddu, Federico Moretti, Prassede Salutari, Maurizio Martelli, Maria Paola Martelli, Mario Luppi, Alessandro Pulsoni, Francesco Zaja, Roberto Cairoli, Fabrizio Pane, Sergio Siragusa, Renato Bassan, Michela Rondoni, Milena Mirabile, Antonino Mulè, Germana Beltrami, Patrizia Zappasodi, Laura Cudillo, Andrea Mengarelli, Antonio Curti, Felicetto Ferrara, Giovanni Rossi, Ernesta Audisio, Giuseppina Spinosa, Alessia Tieghi, Monica Bocchia, Vincenza Martini, Catello Califano, Luigi Rigacci, Agostino Tafuri, Michele Gottardi, Paola Fazi, Marco Vignetti, Francesco Buccisano

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Long-term survival can be achieved in a significant fraction of older patients with core binding factor acute myeloid leukemia treated with intensive chemotherapy by Federico Mosna, Erika Borlenghi, Mark Litzow, John C. Byrd, Cristina Papayannidis, Cristina Tecchio, Felicetto Ferrara, Guido Marcucci, Roberto Cairoli, Elizabeth A. Morgan, Carmela Gurrieri, Cecilia C.S. Yeung, H. Joachim Deeg, Debora Capelli, Anna Candoni, Jason R. Gotlib, Monia Lunghi, Sheeja Pullarkat, Francesco Lanza, Sara Galimberti, Fabio Forghieri, Adriano Venditti, Moreno Festuccia, Ernesta Audisio, Denise Marvalle, Gian Matteo Rigolin, Giovanni Roti, Eros DiBona, Giuseppe Visani, Francesco Albano, Ann-Kathrin Eisfeld, Peter Valent, Gerwin Huls, Gautam Borthakur, Mauro Krampera, Giovanni Martinelli, Nicolaus Kröger, Alessandra Sperotto, Michele Gottardi

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