Ciclosporin in Combination With Irinotecan for Chemoresistant Advanced Colorectal Cancer - Results of PICCOLO, a Large Randomised Trial With Prospective Molecular Stratification by Middleton, G, Brown, SR, Gwyther, S, Maughan, T, Wadsley, J, Chau, I, Richman, S, Olivier, C, Marshall, H, Seymour, M

Panitumumab in Combination With Irinotecan for Chemoresistant Advanced Colorectal Cancer: Results of PICCOLO, a Large Randomised Trial With Prospective Molecular Stratification by Seymour, M, Brown, SR, Richman, S, Middleton, G, Maughan, T, Maisey, N, Hill, M, Olivier, C, Napp, V, Quirke, P

Chemotherapy options in elderly and frail patients with metastatic colorectal cancer (MRC FOCUS2): an open-label, randomised factorial trial. by Seymour, M, Thompson, L, Wasan, H, Middleton, G, Brewster, A, Shepherd, S, O'Mahony, MS, Maughan, T, Parmar, M, Langley, R

Investigating the poor outcomes of BRAF-mutant advanced colorectal cancer: analysis from 2530 patients in randomised clinical trials by Seligmann, JF, Fisher, D, Smith, CG, Richman, SD, Elliott, F, Brown, S, Adams, R, Maughan, T, Quirke, P, Cheadle, J, Seymour, M, Middleton, G

A randomised phase III trial of the pharmacokinetic biomodulation of irinotecan using oral ciclosporin in advanced colorectal cancer: Results of the Panitumumab, Irinotecan and Cic... by Middleton, G, Brown, S, Lowe, C, Maughan, T, Gwyther, S, Oliver, A, Richman, S, Blake, D, Napp, V, Marshall, H, Wadsley, J, Maisey, N, Chau, I, Hill, M, Gollins, S, Myint, S, Slater, S, Wagstaff, J, Bridgewater, J, Seymour, M

A randomised phase III trial of the pharmacokinetic biomodulation of irinotecan using oral ciclosporin in advanced colorectal cancer: results of the Panitumumab, Irinotecan and Cic... by Middleton, G, Brown, S, Lowe, C, Maughan, T, Gwyther, S, Oliver, A, Richman, S, Blake, D, Napp, V, Marshall, H, Wadsley, J, Maisey, N, Chau, I, Hill, M, Gollins, S, Myint, S, Slater, S, Wagstaff, J, Bridgewater, J, Seymour, M

Panitumumab and irinotecan versus irinotecan alone for patients with KRAS wild-type, fluorouracil-resistant advanced colorectal cancer (PICCOLO): A prospectively stratified randomi... by Seymour, M, Brown, SR, Middleton, G, Maughan, T, Richman, S, Gwyther, S, Lowe, C, Seligmann, J, Wadsley, J, Maisey, N, Chau, I, Hill, M, Dawson, L, Falk, S, O'Callaghan, A, Benstead, K, Chambers, P, Oliver, A, Marshall, H, Napp, V, Quirke, P

Panitumumab and irinotecan versus irinotecan alone for patients with KRAS wild-type, fluorouracil-resistant advanced colorectal cancer (PICCOLO): a prospectively stratified randomi... by Seymour, M, Brown, SR, Middleton, G, Maughan, T, Richman, S, Gwyther, S, Lowe, C, Seligmann, J, Wadsley, J, Maisey, N, Chau, I, Hill, M, Dawson, L, Falk, S, O'Callaghan, A, Benstead, K, Chambers, P, Oliver, A, Marshall, H, Napp, V, Quirke, P

The International Stroke Trial (IST): A randomised trial of aspirin, subcutaneous heparin, both, or neither among 19 435 patients with acute ischaemic stroke by Sandercock, P, Collins, R, Counsell, C, Farrell, B, Peto, R, Slattery, J, Warlow, C, Anderson, S, Bowie, A, Boyle, J, Brownlie, A, Charlton, D, Cranswick, G, Day, L, Dennis, M, Dorman, P, Fraser, H, Kaye, M, Lindley, R, Liu, M, MacDonald, C, McCrindle, I, Middleton, G, Perry, D, Scoltock, V

COVID-19 prevalence and mortality in patients with cancer and the effect of primary tumour subtype and patient demographics: a prospective cohort study. by Lee, LYW, Cazier, J-B, Starkey, T, Briggs, SEW, Arnold, R, Bisht, V, Booth, S, Campton, NA, Cheng, VWT, Collins, G, Curley, HM, Earwaker, P, Fittall, MW, Gennatas, S, Goel, A, Hartley, S, Hughes, DJ, Kerr, D, Lee, AJX, Lee, RJ, Lee, SM, Mckenzie, H, Middleton, CP, Murugaesu, N, Newsom-Davis, T, Olsson-Brown, AC, Palles, C, Powles, T, Protheroe, EA, Purshouse, K, Sharma-Oates, A, Sivakumar, S, Smith, AJ, Topping, O, Turnbull, CD, Várnai, C, Briggs, ADM, Middleton, G, Kerr, R, UK Coronavirus Cancer Monitoring Project Team

COVID-19 mortality in patients with cancer on chemotherapy or other anticancer treatments: a prospective cohort study by Lee, LY, Cazier, J-B, Angelis, V, Arnold, R, Bisht, V, Campton, NA, Chackathayil, J, Cheng, VW, Curley, HM, Fittall, MW, Freeman-Mills, L, Gennatas, S, Goel, A, Hartley, S, Hughes, DJ, Kerr, D, Lee, AJ, Lee, RJ, McGrath, SE, Middleton, CP, Murugaesu, N, Newsom-Davis, T, Okines, AF, Olsson-Brown, AC, Palles, C, Pan, Y, Pettengell, R, Powles, T, Protheroe, EA, Purshouse, K, Sharma-Oates, A, Sivakumar, S, Smith, AJ, Starkey, T, Turnbull, CD, Várnai, C, Yousaf, N, UK Coronavirus Monitoring Project Team, Kerr, R, Middleton, G

Namilumab or infliximab compared with standard of care in hospitalised patients with COVID-19 (CATALYST): a randomised, multicentre, multi-arm, multistage, open-label, adaptive, ph... by Fisher, BA, Veenith, T, Slade, D, Gaskell, C, Rowland, M, Whitehouse, T, Scriven, J, Parekh, D, Balasubramaniam, MS, Cooke, G, Morley, N, Gabriel, Z, Wise, MP, Porter, J, McShane, H, Ho, L-P, Newsome, PN, Rowe, A, Sharpe, R, Thickett, DR, Bion, J, Gates, S, Richards, D, Kearns, P, Williams, B, Turner, R, Libri, V, Mussai, F, Middleton, G, Bowden, S, Bangash, M, Gao-Smith, F, Patel, J, Sapey, E, Thomas, M, Coles, M, Watkinson, P, Rahman, N, Angus, B, Mentzer, AJ, Novak, A, Feldman, M, Richter, A, Faustini, S, Bathurst, C, Van de Wiel, J, Mee, S, James, K, Rahman, B

A population-scale temporal case–control evaluation of COVID-19 disease phenotype and related outcome rates in patients with cancer in England (UKCCP) by Starkey, T, Ionescu, MC, Tilby, M, Little, M, Burke, E, Fittall, MW, Khan, S, Liu, JKH, Platt, JR, Mew, R, Tripathy, AR, Watts, I, Williams, ST, Appanna, N, Al-Hajji, Y, Barnard, M, Benny, L, Burnett, A, Bytyci, J, Cattell, EL, Cheng, V, Clark, JJ, Eastlake, L, Gerrand, K, Ghafoor, Q, Grumett, S, Harper-Wynne, C, Kahn, R, Lee, AJX, Lomas, O, Lydon, A, Mckenzie, H, Panneerselvam, H, Pascoe, JS, Patel, G, Patel, V, Potter, VA, Randle, A, Rigg, AS, Robinson, TM, Roylance, R, Roques, TW, Rozmanowski, S, Roux, RL, Shah, K, Sheehan, R, Sintler, M, Swarup, S, Taylor, H, Tillett, T, Tuthill, M, Williams, S, Ying, Y, Beggs, A, Iveson, T, Lee, SM, Middleton, G, Middleton, M, Protheroe, A, Fowler, T, Johnson, P, Lee, LYW