Meningitis-associated pneumococcal serotype 8, ST 53, strain is hypervirulent in a rat model and has non-haemolytic pneumolysin which can be attenuated by liposomes by Annelies Müller, Annelies Müller, Cebile Lekhuleni, Cebile Lekhuleni, Sabrina Hupp, Mignon du Plessis, Mignon du Plessis, Lalaina Holivololona, Eduard Babiychuk, Stephen L. Leib, Denis Grandgirard, Asparouh I. Iliev, Anne von Gottberg, Anne von Gottberg, Lucy J. Hathaway

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Population snapshot of Streptococcus pneumoniae causing invasive disease in South Africa prior to introduction of pneumococcal conjugate vaccines. by Kedibone M Ndlangisa, Mignon du Plessis, Nicole Wolter, Linda de Gouveia, Keith P Klugman, Anne von Gottberg, GERMS-SA

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Meningococcal Disease in South Africa, 1999–2002 by Garry B. Coulson, Meningeal Disease Surveillance in South Africa, Mignon du Plessis, Anthony M. Smith, Linda de Gouveia, Keith P. Klugman, Anne von Gottberg

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Rapid Evaluation of the Xpert^® Xpress CoV-2 <i>plus</i> and Xpert^® Xpress CoV-2/Flu/RSV <i>plus</i> Tests by Lara Dominique Noble, Lesley Erica Scott, Riffat Munir, Mignon Du Plessis, Kim Steegen, Lucia Hans, Puleng Marokane, Pedro Da Silva, Wendy Susan Stevens

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Non-toxigenic Corynebacterium diphtheriae endocarditis: A cluster of five cases by Tamsin Lovelock, Mignon du Plessis, Clinton van der Westhuizen, Jacques T. Janson, Charlene Lawrence, Arifa Parker, Alfonso Pecoraro, Hans Prozesky, Anne von Gottberg, Jantjie Taljaard

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Challenges and clinical relevance of molecular detection of Bordetella pertussis in South Africa by Fahima Moosa, Mignon du Plessis, Nicole Wolter, Maimuna Carrim, Cheryl Cohen, Claire von Mollendorf, Sibongile Walaza, Stefano Tempia, Halima Dawood, Ebrahim Variava, Anne von Gottberg

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Pathogens detected using a syndromic molecular diagnostic platform in patients hospitalized with severe respiratory illness in South Africa in 2017 by Malefu Moleleki, Mignon du Plessis, Kedibone Ndlangisa, Cayla Reddy, Orienka Hellferscee, Omphe Mekgoe, Meredith McMorrow, Sibongile Walaza, Cheryl Cohen, Stefano Tempia, Anne von Gottberg, Nicole Wolter

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Epidemiology and Molecular Identification and Characterization of Mycoplasma pneumoniae, South Africa, 2012–2015 by Maimuna Carrim, Nicole Wolter, Alvaro J. Benitez, Stefano Tempia, Mignon du Plessis, Sibongile Walaza, Fahima Moosa, Maureen H. Diaz, Bernard J. Wolff, Florette K. Treurnicht, Orienka Hellferscee, Halima Dawood, Ebrahim Variava, Cheryl Cohen, Jonas M. Winchell, Anne von Gottberg

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Incidence and Transmission Dynamics of Bordetella pertussis Infection in Rural and Urban Communities, South Africa, 2016‒2018 by Fahima Moosa, Stefano Tempia, Jackie Kleynhans, Meredith McMorrow, Jocelyn Moyes, Mignon du Plessis, Maimuna Carrim, Florette K. Treurnicht, Orienka Helferscee, Thulisa Mkhencele, Azwifarwi Mathunjwa, Neil A. Martinson, Kathleen Kahn, Limakatso Lebina, Floidy Wafawanaka, Cheryl Cohen, Anne von Gottberg, Nicole Wolter

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Case-fatality and sequelae following acute bacterial meningitis in South Africa, 2016 through 2020 by Susan Meiring, Cheryl Cohen, Linda de Gouveia, Mignon du Plessis, Vanessa Quan, Jackie Kleynhans, Colin Menezes, Gary Reubenson, Halima Dawood, Maphoshane Nchabeleng, Mohamed Said, Nomonde Mvelase, Prasha Mahabeer, Rispah Chomba, Ruth Lekalakala, Trusha Nana, Vindana Chibabhai, Marianne Black, Anne von Gottberg

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Molecular diagnostic assays for the detection of common bacterial meningitis pathogens: A narrative review by Kanny Diallo, Vitalis F. Feteh, Lilian Ibe, Martin Antonio, Dominique A. Caugant, Mignon du Plessis, Ala-Eddine Deghmane, Ian M. Feavers, Katya Fernandez, LeAnne M. Fox, Charlene M.C. Rodrigues, Olivier Ronveaux, Muhamed-Kheir Taha, Xin Wang, Angela B. Brueggemann, Martin C.J. Maiden, Odile B. Harrison

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Characteristics of infections with ancestral, Beta and Delta variants of SARS-CoV-2 in the PHIRST-C community cohort study, South Africa, 2020-2021 by Cheryl Cohen, Jackie Kleynhans, Anne von Gottberg, Meredith L. McMorrow, Nicole Wolter, Jinal N. Bhiman, Jocelyn Moyes, Mignon du Plessis, Maimuna Carrim, Amelia Buys, Neil A. Martinson, Kathleen Kahn, Stephen Tollman, Limakatso Lebina, Floidy Wafawanaka, Jacques du Toit, Francesc Xavier Gómez-Olivé, Fatimah S. Dawood, Thulisa Mkhencele, for the PHIRST group, Stefano Tempia

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Clinical severity of SARS-CoV-2 Omicron BA.4 and BA.5 lineages compared to BA.1 and Delta in South Africa by Nicole Wolter, Waasila Jassat, Sibongile Walaza, Richard Welch, Harry Moultrie, Michelle J. Groome, Daniel Gyamfi Amoako, Josie Everatt, Jinal N. Bhiman, Cathrine Scheepers, Naume Tebeila, Nicola Chiwandire, Mignon du Plessis, Nevashan Govender, Arshad Ismail, Allison Glass, Koleka Mlisana, Wendy Stevens, Florette K. Treurnicht, Kathleen Subramoney, Zinhle Makatini, Nei-yuan Hsiao, Raveen Parboosing, Jeannette Wadula, Hannah Hussey, Mary-Ann Davies, Andrew Boulle, Anne von Gottberg, Cheryl Cohen

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International genomic definition of pneumococcal lineages, to contextualise disease, antibiotic resistance and vaccine impactResearch in context by Rebecca A. Gladstone, Stephanie W. Lo, John A. Lees, Nicholas J. Croucher, Andries J. van Tonder, Jukka Corander, Andrew J. Page, Pekka Marttinen, Leon J. Bentley, Theresa J. Ochoa, Pak Leung Ho, Mignon du Plessis, Jennifer E. Cornick, Brenda Kwambana-Adams, Rachel Benisty, Susan A. Nzenze, Shabir A. Madhi, Paulina A. Hawkins, Dean B. Everett, Martin Antonio, Ron Dagan, Keith P. Klugman, Anne von Gottberg, Lesley McGee, Robert F. Breiman, Stephen D. Bentley

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Understanding pneumococcal serotype 1 biology through population genomic analysis by Chrispin Chaguza, Jennifer E. Cornick, Simon R. Harris, Cheryl P. Andam, Laura Bricio-Moreno, Marie Yang, Feyruz Yalcin, Sani Ousmane, Shanil Govindpersad, Madikay Senghore, Chinelo Ebruke, Mignon Du Plessis, Anmol M. Kiran, Gerd Pluschke, Betuel Sigauque, Lesley McGee, Keith P. Klugman, Paul Turner, Jukka Corander, Julian Parkhill, Jean-Marc Collard, Martin Antonio, Anne von Gottberg, Robert S. Heyderman, Neil French, Aras Kadioglu, William P. Hanage, Dean B. Everett, Stephen D. Bentley, for the PAGe Consortium

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Global emergence and population dynamics of divergent serotype 3 CC180 pneumococci. by Taj Azarian, Patrick K Mitchell, Maria Georgieva, Claudette M Thompson, Amel Ghouila, Andrew J Pollard, Anne von Gottberg, Mignon du Plessis, Martin Antonio, Brenda A Kwambana-Adams, Stuart C Clarke, Dean Everett, Jennifer Cornick, Ewa Sadowy, Waleria Hryniewicz, Anna Skoczynska, Jennifer C Moïsi, Lesley McGee, Bernard Beall, Benjamin J Metcalf, Robert F Breiman, P L Ho, Raymond Reid, Katherine L O'Brien, Rebecca A Gladstone, Stephen D Bentley, William P Hanage

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Joint sequencing of human and pathogen genomes reveals the genetics of pneumococcal meningitis by John A. Lees, Bart Ferwerda, Philip H. C. Kremer, Nicole E. Wheeler, Mercedes Valls Serón, Nicholas J. Croucher, Rebecca A. Gladstone, Hester J. Bootsma, Nynke Y. Rots, Alienke J. Wijmega-Monsuur, Elisabeth A. M. Sanders, Krzysztof Trzciński, Anne L. Wyllie, Aeilko H. Zwinderman, Leonard H. van den Berg, Wouter van Rheenen, Jan H. Veldink, Zitta B. Harboe, Lene F. Lundbo, Lisette C. P. G. M. de Groot, Natasja M. van Schoor, Nathalie van der Velde, Lars H. Ängquist, Thorkild I. A. Sørensen, Ellen A. Nohr, Alexander J. Mentzer, Tara C. Mills, Julian C. Knight, Mignon du Plessis, Susan Nzenze, Jeffrey N. Weiser, Julian Parkhill, Shabir Madhi, Thomas Benfield, Anne von Gottberg, Arie van der Ende, Matthijs C. Brouwer, Jeffrey C. Barrett, Stephen D. Bentley, Diederik van de Beek

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Trends in invasive bacterial diseases during the first 2 years of the COVID-19 pandemic: analyses of prospective surveillance data from 30 countries and territories in the IRIS Con... by David Shaw, MBBCh, Raquel Abad, PhD, Zahin Amin-Chowdhury, MSc, Adriana Bautista, MSc, Desiree Bennett, PhD, Karen Broughton, MSc, Bin Cao, ProfMD, Carlo Casanova, PhD, Eun Hwa Choi, ProfMD, Yiu-Wai Chu, PhD, Heike Claus, PhD, Juliana Coelho, PhD, Mary Corcoran, PhD, Simon Cottrell, PhD, Robert Cunney, MB, Lize Cuypers, PhD, Tine Dalby, PhD, Heather Davies, NZCS, Linda de Gouveia, NatDipMedTech, Ala-Eddine Deghmane, PhD, Walter Demczuk, BSc, Stefanie Desmet, PhD, Mirian Domenech, PhD, Richard Drew, MD, Mignon du Plessis, PhD, Carolina Duarte, PhD, Helga Erlendsdóttir, ProfMSc, Norman K Fry, PhD, Kurt Fuursted, MD, Thomas Hale, ProfPhD, Desiree Henares, PhD, Birgitta Henriques-Normark, ProfMD, Markus Hilty, PhD, Steen Hoffmann, MD, Hilary Humphreys, ProfMD, Margaret Ip, ProfMSc, Susanne Jacobsson, PhD, Christopher Johnson, PhD, Jillian Johnston, MBBS, Keith A Jolley, PhD, Aníbal Kawabata, Jana Kozakova, MD, Karl G Kristinsson, ProfMD, Pavla Krizova, MD, Alicja Kuch, PhD, Shamez Ladhani, MD, Thiên-Trí Lâm, MD, María Eugenia León, MSc, Laura Lindholm, MSc, David Litt, PhD, Martin C J Maiden, ProfPhD, Irene Martin, BSc, Delphine Martiny, ProfPhD, Wesley Mattheus, PhD, Noel D McCarthy, ProfDPhil, Mary Meehan, PhD, Susan Meiring, MBChB, Paula Mölling, PhD, Eva Morfeldt, PhD, Julie Morgan, HND, Robert Mulhall, PhD, Carmen Muñoz-Almagro, ProfMD, David Murdoch, ProfMD, Joy Murphy, BA Hons, Martin Musilek, PhD, Alexandre Mzabi, MD, Ludmila Novakova, MSc, Shahin Oftadeh, PhD, Amaresh Perez-Argüello, MLT, Maria Pérez-Vázquez, PhD, Monique Perrin, MD, Malorie Perry, MSc, Benoit Prevost, PhD, Maria Roberts, BSc(Hons), Assaf Rokney, PhD, Merav Ron, PhD, Olga Marina Sanabria, MPH, Kevin J Scott, PhD, Carmen Sheppard, PhD, Lotta Siira, PhD, Vitali Sintchenko, ProfPhD, Anna Skoczyńska, ProfPhD, Monica Sloan, Hans-Christian Slotved, DMSc, Andrew J Smith, ProfFRCPath, Anneke Steens, PhD, Muhamed-Kheir Taha, ProfMD, Maija Toropainen, PhD, Georgina Tzanakaki, ProfPhD, Anni Vainio, PhD, Mark P G van der Linden, PhD, Nina M van Sorge, ProfPhD, Emmanuelle Varon, MD, Sandra Vohrnova, MD, Anne von Gottberg, ProfPhD, Jose Yuste, PhD, Rosemeire Zanella, PhD, Fei Zhou, PhD, Angela B Brueggemann, ProfDPhil

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Changes in the incidence of invasive disease due to Streptococcus pneumoniae, Haemophilus influenzae, and Neisseria meningitidis during the COVID-19 pandemic in 26 countries and te... by Angela B Brueggemann, ProfDPhil, Melissa J Jansen van Rensburg, ProfDPhil, David Shaw, MD, Noel D McCarthy, ProfDPhil, Keith A Jolley, PhD, Martin C J Maiden, ProfPhD, Mark P G van der Linden, PhD, Zahin Amin-Chowdhury, BSc, Désirée E Bennett, PhD, Ray Borrow, PhD, Maria-Cristina C Brandileone, PhD, Karen Broughton, MSc, Ruth Campbell, Bin Cao, ProfMD, Carlo Casanova, PhD, Eun Hwa Choi, ProfMD, Yiu Wai Chu, PhD, Stephen A Clark, PhD, Heike Claus, PhD, Juliana Coelho, PhD, Mary Corcoran, PhD, Simon Cottrell, PhD, Robert J Cunney, MD, Tine Dalby, PhD, Heather Davies, NZCS, Linda de Gouveia, NatDipMicro, Ala-Eddine Deghmane, PhD, Walter Demczuk, BSc, Stefanie Desmet, PharmD, Richard J Drew, MD, Mignon du Plessis, PhD, Helga Erlendsdottir, ProfMSc, Norman K Fry, PhD, Kurt Fuursted, MD, Steve J Gray, PhD, Birgitta Henriques-Normark, ProfMD, Thomas Hale, PhD, Markus Hilty, PhD, Steen Hoffmann, MD, Hilary Humphreys, ProfMD, Margaret Ip, MD, Susanne Jacobsson, PhD, Jillian Johnston, MBBS, Jana Kozakova, MD, Karl G Kristinsson, ProfMD, Pavla Krizova, MD, Alicja Kuch, PhD, Shamez N Ladhani, MD, Thiên-Trí Lâm, MD, Vera Lebedova, MD, Laura Lindholm, MSc, David J Litt, PhD, Irene Martin, BSc, Delphine Martiny, ProfPhD, Wesley Mattheus, PhD, Martha McElligott, PhD, Mary Meehan, PhD, Susan Meiring, MBChB, Paula Mölling, PhD, Eva Morfeldt, PhD, Julie Morgan, HND, Robert M Mulhall, PhD, Carmen Muñoz-Almagro, ProfMD, David R Murdoch, ProfMD, Joy Murphy, BA Hons, Martin Musilek, PhD, Alexandre Mzabi, MD, Amaresh Perez-Argüello, MLT, Monique Perrin, MD, Malorie Perry, MSc, Alba Redin, BSc, Richard Roberts, MPH, Maria Roberts, BSc, Assaf Rokney, PhD, Merav Ron, PhD, Kevin J Scott, PhD, Carmen L Sheppard, PhD, Lotta Siira, PhD, Anna Skoczyńska, ProfPhD, Monica Sloan, Hans-Christian Slotved, PhD, Andrew J Smith, ProfPhD, Joon Young Song, MD, Muhamed-Kheir Taha, MD, Maija Toropainen, PhD, Dominic Tsang, MD, Anni Vainio, PhD, Nina M van Sorge, PhD, Emmanuelle Varon, MD, Jiri Vlach, PhD, Ulrich Vogel, ProfMD, Sandra Vohrnova, MD, Anne von Gottberg, PhD, Rosemeire C Zanella, PhD, Fei Zhou, PhD

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