334 Identification of novel plasma protein biomarkers for diagnosis and prediction of Alzheimer’s disease in African Americans by Lindsey Kuchenbecker, Joseph S Reddy, Minerva M Carrasquillo

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Multiple insulin degrading enzyme variants alter in vitro reporter gene expression. by Olivia Belbin, Olivia Belbin, Michael Crump, Gina D Bisceglio, Minerva M Carrasquillo, Kevin Morgan, Steven G Younkin

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Comparative evaluation for the globin gene depletion methods for mRNA sequencing using the whole blood-derived total RNAs by Jin Sung Jang, Brianna Berg, Eileen Holicky, Bruce Eckloff, Mark Mutawe, Minerva M. Carrasquillo, Nilüfer Ertekin-Taner, Julie M. Cuninngham

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Evaluation of the role of SNCA variants in survival without neurological disease. by Michael G Heckman, Alexandra I Soto-Ortolaza, Nancy N Diehl, Minerva M Carrasquillo, Ryan J Uitti, Zbigniew K Wszolek, Neill R Graff-Radford, Owen A Ross

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TMEM106B haplotypes have distinct gene expression patterns in aged brain by Yingxue Ren, Marka van Blitterswijk, Mariet Allen, Minerva M. Carrasquillo, Joseph S. Reddy, Xue Wang, Thomas G. Beach, Dennis W. Dickson, Nilüfer Ertekin-Taner, Yan W. Asmann, Rosa Rademakers

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Correction to: Deciphering cellular transcriptional alterations in Alzheimer’s disease brains by Xue Wang, Mariet Allen, Shaoyu Li, Zachary S. Quicksall, Tulsi A. Patel, Troy P. Carnwath, Joseph S. Reddy, Minerva M. Carrasquillo, Sarah J. Lincoln, Thuy T. Nguyen, Kimberly G. Malphrus, Dennis W. Dickson, Julia E. Crook, Yan W. Asmann, Nilüfer Ertekin-Taner

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Deciphering cellular transcriptional alterations in Alzheimer’s disease brains by Xue Wang, Mariet Allen, Shaoyu Li, Zachary S. Quicksall, Tulsi A. Patel, Troy P. Carnwath, Joseph S. Reddy, Minerva M. Carrasquillo, Sarah J. Lincoln, Thuy T. Nguyen, Kimberly G. Malphrus, Dennis W. Dickson, Julia E. Crook, Yan W. Asmann, Nilüfer Ertekin-Taner

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Impact of variant-level batch effects on identification of genetic risk factors in large sequencing studies. by Daniel P Wickland, Yingxue Ren, Jason P Sinnwell, Joseph S Reddy, Cyril Pottier, Vivekananda Sarangi, Minerva M Carrasquillo, Owen A Ross, Steven G Younkin, Nilüfer Ertekin-Taner, Rosa Rademakers, Matthew E Hudson, Liudmila Sergeevna Mainzer, Joanna M Biernacka, Yan W Asmann

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Linking protective GAB2 variants, increased cortical GAB2 expression and decreased Alzheimer's disease pathology. by Fanggeng Zou, Olivia Belbin, Olivia Belbin, Minerva M Carrasquillo, Oliver J Culley, Talisha A Hunter, Li Ma, Gina D Bisceglio, Mariet Allen, Dennis W Dickson, Neill R Graff-Radford, Ronald C Petersen, Genetic and Environmental Risk for Alzheimer’s disease (GERAD1) Consortium, Kevin Morgan, Steven G Younkin

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Modulating innate immune activation states impacts the efficacy of specific Aβ immunotherapy by Yona Levites, Cory Funk, Xue Wang, Paramita Chakrabarty, Karen N. McFarland, Baxter Bramblett, Veronica O’Neal, Xufei Liu, Thomas Ladd, Max Robinson, Mariet Allen, Minerva M. Carrasquillo, Dennis Dickson, Pedro Cruz, Danny Ryu, Hong-Dong Li, Nathan D. Price, NIlüfer Ertekin-Taner, Todd E. Golde

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Exonic Re-Sequencing of the Chromosome 2q24.3 Parkinson's Disease Locus. by Catherine Labbé, Kotaro Ogaki, Oswaldo Lorenzo-Betancor, Minerva M Carrasquillo, Michael G Heckman, Allan McCarthy, Alexandra I Soto-Ortolaza, Ronald L Walton, Timothy Lynch, Joanna Siuda, Grzegorz Opala, Anna Krygowska-Wajs, Maria Barcikowska, Krzysztof Czyzewski, Dennis W Dickson, Ryan J Uitti, Zbigniew K Wszolek, Owen A Ross

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Cross species systems biology discovers glial DDR2, STOM, and KANK2 as therapeutic targets in progressive supranuclear palsy by Yuhao Min, Xue Wang, Özkan İş, Tulsi A. Patel, Junli Gao, Joseph S. Reddy, Zachary S. Quicksall, Thuy Nguyen, Shu Lin, Frederick Q. Tutor-New, Jessica L. Chalk, Adriana O. Mitchell, Julia E. Crook, Peter T. Nelson, Linda J. Van Eldik, Todd E. Golde, Minerva M. Carrasquillo, Dennis W. Dickson, Ke Zhang, Mariet Allen, Nilüfer Ertekin-Taner

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Systematic analysis of dark and camouflaged genes reveals disease-relevant genes hiding in plain sight by Mark T. W. Ebbert, Tanner D. Jensen, Karen Jansen-West, Jonathon P. Sens, Joseph S. Reddy, Perry G. Ridge, John S. K. Kauwe, Veronique Belzil, Luc Pregent, Minerva M. Carrasquillo, Dirk Keene, Eric Larson, Paul Crane, Yan W. Asmann, Nilufer Ertekin-Taner, Steven G. Younkin, Owen A. Ross, Rosa Rademakers, Leonard Petrucelli, John D. Fryer

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Alzheimer’s disease and progressive supranuclear palsy share similar transcriptomic changes in distinct brain regions by Xue Wang, Mariet Allen, Özkan İş, Joseph S. Reddy, Frederick Q. Tutor-New, Monica Castanedes Casey, Minerva M. Carrasquillo, Stephanie R. Oatman, Yuhao Min, Yan W. Asmann, Cory Funk, Thuy Nguyen, Charlotte C.G. Ho, Kimberly G. Malphrus, Nicholas T. Seyfried, Allan I. Levey, Steven G. Younkin, Melissa E. Murray, Dennis W. Dickson, Nathan D. Price, Todd E. Golde, Nilüfer Ertekin-Taner

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Identifying drug targets for neurological and psychiatric disease via genetics and the brain transcriptome. by Denis A Baird, Jimmy Z Liu, Jie Zheng, Solveig K Sieberts, Thanneer Perumal, Benjamin Elsworth, Tom G Richardson, Chia-Yen Chen, Minerva M Carrasquillo, Mariet Allen, Joseph S Reddy, Philip L De Jager, Nilufer Ertekin-Taner, Lara M Mangravite, Ben Logsdon, Karol Estrada, Philip C Haycock, Gibran Hemani, Heiko Runz, George Davey Smith, Tom R Gaunt, AMP-AD eQTL working group

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Genome-wide association study of brain biochemical phenotypes reveals distinct genetic architecture of Alzheimer’s disease related proteins by Stephanie R. Oatman, Joseph S. Reddy, Zachary Quicksall, Minerva M. Carrasquillo, Xue Wang, Chia-Chen Liu, Yu Yamazaki, Thuy T. Nguyen, Kimberly Malphrus, Michael Heckman, Kristi Biswas, Kwangsik Nho, Matthew Baker, Yuka A. Martens, Na Zhao, Jun Pyo Kim, Shannon L. Risacher, Rosa Rademakers, Andrew J. Saykin, Michael DeTure, Melissa E. Murray, Takahisa Kanekiyo, for the Alzheimer’s Disease Neuroimaging Initiative, Dennis W. Dickson, Guojun Bu, Mariet Allen, Nilüfer Ertekin-Taner

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Association of ABI3 and PLCG2 missense variants with disease risk and neuropathology in Lewy body disease and progressive supranuclear palsy by Samantha L. Strickland, Hélène Morel, Christian Prusinski, Mariet Allen, Tulsi A. Patel, Minerva M. Carrasquillo, Olivia J. Conway, Sarah J. Lincoln, Joseph S. Reddy, Thuy Nguyen, Kimberly G. Malphrus, Alexandra I. Soto, Ronald L. Walton, Julia E. Crook, Melissa E. Murray, Bradley F. Boeve, Ronald C. Petersen, John A. Lucas, Tanis J. Ferman, Ryan J. Uitti, Zbigniew K. Wszolek, Owen A. Ross, Neill R. Graff-Radford, Dennis W. Dickson, Nilüfer Ertekin-Taner

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ABI3 and PLCG2 missense variants as risk factors for neurodegenerative diseases in Caucasians and African Americans by Olivia J Conway, Minerva M Carrasquillo, Xue Wang, Jenny M Bredenberg, Joseph S Reddy, Samantha L Strickland, Curtis S Younkin, Jeremy D Burgess, Mariet Allen, Sarah J Lincoln, Thuy Nguyen, Kimberly G Malphrus, Alexandra I Soto, Ronald L Walton, Bradley F Boeve, Ronald C Petersen, John A Lucas, Tanis J Ferman, William P Cheshire, Jay A van Gerpen, Ryan J Uitti, Zbigniew K Wszolek, Owen A Ross, Dennis W Dickson, Neill R Graff-Radford, Nilüfer Ertekin-Taner

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Transcriptomic analysis to identify genes associated with selective hippocampal vulnerability in Alzheimer’s disease by Angela M. Crist, Kelly M. Hinkle, Xue Wang, Christina M. Moloney, Billie J. Matchett, Sydney A. Labuzan, Isabelle Frankenhauser, Nkem O. Azu, Amanda M. Liesinger, Elizabeth R. Lesser, Daniel J. Serie, Zachary S. Quicksall, Tulsi A. Patel, Troy P. Carnwath, Michael DeTure, Xiaojia Tang, Ronald C. Petersen, Ranjan Duara, Neill R. Graff-Radford, Mariet Allen, Minerva M. Carrasquillo, Hu Li, Owen A. Ross, Nilüfer Ertekin-Taner, Dennis W. Dickson, Yan W. Asmann, Rickey E. Carter, Melissa E. Murray

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Gliovascular transcriptional perturbations in Alzheimer’s disease reveal molecular mechanisms of blood brain barrier dysfunction by Özkan İş, Xue Wang, Joseph S. Reddy, Yuhao Min, Elanur Yilmaz, Prabesh Bhattarai, Tulsi Patel, Jeremiah Bergman, Zachary Quicksall, Michael G. Heckman, Frederick Q. Tutor-New, Birsen Can Demirdogen, Launia White, Shunsuke Koga, Vincent Krause, Yasuteru Inoue, Takahisa Kanekiyo, Mehmet Ilyas Cosacak, Nastasia Nelson, Annie J. Lee, Badri Vardarajan, Richard Mayeux, Naomi Kouri, Kaancan Deniz, Troy Carnwath, Stephanie R. Oatman, Laura J. Lewis-Tuffin, Thuy Nguyen, for the Alzheimer’s Disease Neuroimaging Initiative, Minerva M. Carrasquillo, Jonathan Graff-Radford, Ronald C. Petersen, Clifford R. Jr Jack, Kejal Kantarci, Melissa E. Murray, Kwangsik Nho, Andrew J. Saykin, Dennis W. Dickson, Caghan Kizil, Mariet Allen, Nilüfer Ertekin-Taner

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