Fusion InPipe, an integrative pipeline for gene fusion detection from RNA-seq data in acute pediatric leukemia by Clara Vicente-Garcés, Joan Maynou, Joan Maynou, Guerau Fernández, Guerau Fernández, Elena Esperanza-Cebollada, Montserrat Torrebadell, Montserrat Torrebadell, Montserrat Torrebadell, Albert Català, Albert Català, Albert Català, Susana Rives, Susana Rives, Susana Rives, Mireia Camós, Mireia Camós, Mireia Camós, Nerea Vega-García, Nerea Vega-García

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Technical Validation and Clinical Utility of an NGS Targeted Panel to Improve Molecular Characterization of Pediatric Acute Leukemia by Clara Vicente-Garcés, Clara Vicente-Garcés, Elena Esperanza-Cebollada, Elena Esperanza-Cebollada, Sara Montesdeoca, Sara Montesdeoca, Montserrat Torrebadell, Montserrat Torrebadell, Montserrat Torrebadell, Susana Rives, Susana Rives, Susana Rives, José Luis Dapena, José Luis Dapena, Albert Català, Albert Català, Albert Català, Nuria Conde, Nuria Conde, Mireia Camós, Mireia Camós, Mireia Camós, Nerea Vega-García, Nerea Vega-García

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PB1700: GENOMIC CHARACTERIZATION OF CHILDHOOD B-OTHER ACUTE LEUKEMIA PATIENTS BY RNA SEQUENCING IN A SINGLE CENTER by Clara Vicente Garcés, Guerau Fernández, Elena Esperanza Cebollada, Susana Rives, Jose Luis Dapena, Mireia Camos Guijosa, Nerea Vega García

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Bone marrow MSC from pediatric patients with B-ALL highly immunosuppress T-cell responses but do not compromise CD19-CAR T-cell activity by Samanta Romina Zanetti, Paola Alejandra Romecin, Meritxell Vinyoles, Manel Juan, José Luis Fuster, Mireia Cámos, Sergi Querol, Mario Delgado, Pablo Menendez

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TIM3, a human acute myeloid leukemia stem cell marker, does not enrich for leukemia-initiating stem cells in B-cell acute lymphoblastic leukemia by Clara Bueno, Alba Martínez, Paola Alejandra Romecin, Samanta Romina Zanetti, Ricky Tirtakusuma, Eulalia Genesca, Mireia Camós, Manuel Ramírez-Orellana, Eduardo Anguita, Paola Ballerini, Franco Locatelli, José Luis Fuster, Pablo Menéndez

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P348: GENOMIC CHARACTERIZATION OF RELAPSED/REFRACTORY B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA PEDIATRIC PATIENTS UNDERGOING CAR-T TREATMENT IN A SINGLE CENTER by Elena Esperanza Cebollada, Clara Vicente Garcés, Anna Alsonso, Esther Cuatrecasas Capdevila, Sandra Andreu, Alba Crespo Carrasco, Mercè Richarte, Sara Montesdeoca, Montserrat Torrebadell, Mireia Camos Guijosa, Susana Rives, Nerea Vega García

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Expanded and highly active proliferation centers identify a histological subtype of chronic lymphocytic leukemia (“accelerated” chronic lymphocytic leukemia) with aggressive clinic... by Eva Giné, Antoni Martinez, Neus Villamor, Armando López-Guillermo, Mireia Camos, Daniel Martinez, Jordi Esteve, Xavier Calvo, Ana Muntañola, Pau Abrisqueta, Maria Rozman, Ciril Rozman, Francesc Bosch, Elias Campo, Emili Montserrat

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β‐Catenin activity induces an RNA biosynthesis program promoting therapy resistance in T‐cell acute lymphoblastic leukemia by Violeta García‐Hernández, David Arambilet, Yolanda Guillén, Teresa Lobo‐Jarne, María Maqueda, Christos Gekas, Jessica González, Arnau Iglesias, Nerea Vega‐García, Inés Sentís, Juan L Trincado, Ian Márquez‐López, Holger Heyn, Mireia Camós, Lluis Espinosa, Anna Bigas

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Low input capture Hi-C (liCHi-C) identifies promoter-enhancer interactions at high-resolution by Laureano Tomás-Daza, Llorenç Rovirosa, Paula López-Martí, Andrea Nieto-Aliseda, François Serra, Ainoa Planas-Riverola, Oscar Molina, Rebecca McDonald, Cedric Ghevaert, Esther Cuatrecasas, Dolors Costa, Mireia Camós, Clara Bueno, Pablo Menéndez, Alfonso Valencia, Biola M. Javierre

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The relapsed acute lymphoblastic leukemia network (ReALLNet): a multidisciplinary project from the spanish society of pediatric hematology and oncology (SEHOP) by Pablo Velasco, Francisco Bautista, Alba Rubio, Yurena Aguilar, Susana Rives, Susana Rives, Jose L. Dapena, Jose L. Dapena, Antonio Pérez, Antonio Pérez, Antonio Pérez, Manuel Ramirez, Cristina Saiz-Ladera, Elisa Izquierdo, Elisa Izquierdo, Adela Escudero, Adela Escudero, Mireia Camós, Mireia Camós, Mireia Camós, Nerea Vega-García, Nerea Vega-García, Margarita Ortega, Margarita Ortega, Gloria Hidalgo-Gómez, Gloria Hidalgo-Gómez, Carlos Palacio, Carlos Palacio, Pablo Menéndez, Pablo Menéndez, Pablo Menéndez, Pablo Menéndez, Clara Bueno, Clara Bueno, Clara Bueno, Clara Bueno, Joan Montero, Joan Montero, Paola A. Romecín, Paola A. Romecín, Santiago Zazo, Federico Alvarez, Juan Parras, Carmen Ortega-Sabater, Salvador Chulián, Salvador Chulián, María Rosa, María Rosa, Davide Cirillo, Elena García, Jorge García, Albert Manzano-Muñoz, Albert Manzano-Muñoz, Alfredo Minguela, Alfredo Minguela, Jose L. Fuster, Jose L. Fuster

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Measurable Residual Disease Assessed by Flow-Cytometry Is a Stable Prognostic Factor for Pediatric T-Cell Acute Lymphoblastic Leukemia in Consecutive SEHOP Protocols Whereas the Im... by Nerea Vega-García, Nerea Vega-García, Sara Perez-Jaume, Elena Esperanza-Cebollada, Elena Esperanza-Cebollada, Clara Vicente-Garcés, Clara Vicente-Garcés, Montserrat Torrebadell, Montserrat Torrebadell, Montserrat Torrebadell, Antonio Jiménez-Velasco, Margarita Ortega, Marta Llop, Marta Llop, Lorea Abad, José Manuel Vagace, Alfredo Minguela, Marta Pratcorona, Joaquín Sánchez-Garcia, Clara B. García-Calderón, María Teresa Gómez-Casares, Estela Martín-Clavero, Adela Escudero, Marta Riñón Martinez-Gallo, Luz Muñoz, María Rosario Velasco, Marina García-Morin, Albert Català, Albert Català, Albert Català, Antonia Pascual, Pablo Velasco, José Mª. Fernández, Alvaro Lassaletta, José Luis Fuster, Isabel Badell, Águeda Molinos-Quintana, Antonio Molinés, Pilar Guerra-García, Pilar Guerra-García, Antonio Pérez-Martínez, Antonio Pérez-Martínez, Miriam García-Abós, Reyes Robles Ortiz, Sandra Pisa, Rosa Adán, Cristina Díaz de Heredia, José Luis Dapena, José Luis Dapena, Susana Rives, Susana Rives, Susana Rives, Manuel Ramírez-Orellana, Mireia Camós, Mireia Camós, Mireia Camós

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Prognostic value of FLT3 mutations in patients with acute promyelocytic leukemia treated with all-trans retinoic acid and anthracycline monochemotherapy by Eva Barragán, Pau Montesinos, Mireia Camos, Marcos González, Maria J. Calasanz, José Román-Gómez, Maria T. Gómez-Casares, Rosa Ayala, Javier López, Óscar Fuster, Dolors Colomer, Carmen Chillón, María J. Larrayoz, Pedro Sánchez-Godoy, José González-Campos, Félix Manso, Maria L. Amador, Edo Vellenga, Bob Lowenberg, Miguel A. Sanz

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Clonal heterogeneity and rates of specific chromosome gains are risk predictors in childhood high‐hyperdiploid B‐cell acute lymphoblastic leukemia by Mireia Ramos‐Muntada, Juan L. Trincado, Joan Blanco, Clara Bueno, Virginia C. Rodríguez‐Cortez, Alex Bataller, Belén López‐Millán, Claire Schwab, Margarita Ortega, Pablo Velasco, Maria L. Blanco, Josep Nomdedeu, Manuel Ramírez‐Orellana, Alfredo Minguela, Jose L. Fuster, Esther Cuatrecasas, Mireia Camós, Paola Ballerini, Gabriele Escherich, Judith Boer, Monique DenBoer, Jesús M. Hernández‐Rivas, Maria J. Calasanz, Giovanni Cazzaniga, Christine J. Harrison, Pablo Menéndez, Oscar Molina

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