The SOFA score—development, utility and challenges of accurate assessment in clinical trials by Simon Lambden, Pierre Francois Laterre, Mitchell M. Levy, Bruno Francois

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Improving the care of sepsis: Between system redesign and professional responsibility: A roundtable discussion in the world sepsis day, September 25, 2013, Riyadh, Saudi Arabia by Yaseen Arabi, Ahmed Alamry, Mitchell M. Levy, Saadi Taher, Abdellatif M. Marini

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Effect of Dexmedetomidine on duration of mechanical ventilation in septic patients: a systematic review and meta-analysis by Peifen Chen, Jihong Jiang, Yunhe Zhang, Guobao Li, Zhihui Qiu, Mitchell M. Levy, Baoji Hu

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Time to treatment and mortality for clinical sepsis subtypes by Anne Yang, Jason N. Kennedy, Katherine M. Reitz, Gary Phillips, Kathleen M. Terry, Mitchell M. Levy, Derek C. Angus, Christopher W. Seymour

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Correlation Between Restraint Use and Engaging Family Members in the Care of ICU Patients by Sarah J. Hochendoner, MD, Gianluca Villa, MD, Emily Sokol, MPH, Mitchell M. Levy, MD, Jason M. Aliotta, MD, Timothy H. Amass, MD, ScM

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Validation of END-of-life ScorING-system to identify the dying patient: a prospective analysis by Gianluca Villa, Timothy Amass, Rosa Giua, Iacopo Lanini, Cosimo Chelazzi, Lorenzo Tofani, Rory McFadden, A. Raffaele De Gaudio, Sean OMahony, Mitchell M. Levy, Stefano Romagnoli

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Assessment of implementation methods in sepsis: study protocol for a cluster-randomized hybrid type 2 trial by Hannah E. Frank, Laura Evans, Gary Phillips, RPhillip Dellinger, Jessyca Goldstein, Lori Harmon, David Portelli, Nima Sarani, Christa Schorr, Kathleen M. Terry, Sean R. Townsend, Mitchell M. Levy

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The association between household and neighborhood characteristics and COVID-19 related ICU admissions by Andrew H. Stephen, Sarah B. Andrea, Debasree Banerjee, Mohammed Arafeh, Morgan Askew, Stephanie N. Lueckel, Tareq Kheirbek, Leonard A. Mermel, Charles A. Adams, Jr., Mitchell M. Levy, Daithi S. Heffernan

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Changes in the process of alternative RNA splicing results in soluble B and T lymphocyte attenuator with biological and clinical implications in critical illness by Sean F. Monaghan, Debasree Banerjee, Chun-Shiang Chung, Joanne Lomas-Neira, Kamil J. Cygan, Christy L. Rhine, William G. Fairbrother, Daithi S. Heffernan, Mitchell M. Levy, William G. Cioffi, Alfred Ayala

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Deep RNA sequencing of intensive care unit patients with COVID-19 by Alger M. Fredericks, Maximilian S. Jentzsch, William G. Cioffi, Maya Cohen, William G. Fairbrother, Shivam J. Gandhi, Elizabeth O. Harrington, Gerard J. Nau, Jonathan S. Reichner, Corey E. Ventetuolo, Mitchell M. Levy, Alfred Ayala, Sean F. Monaghan

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Identification and mechanistic basis of non-ACE2 blocking neutralizing antibodies from COVID-19 patients with deep RNA sequencing and molecular dynamics simulations by Alger M. Fredericks, Kyle W. East, Yuanjun Shi, Jinchan Liu, Federica Maschietto, Alfred Ayala, William G. Cioffi, Maya Cohen, William G. Fairbrother, Craig T. Lefort, Gerard J. Nau, Mitchell M. Levy, Jimin Wang, Victor S. Batista, George P. Lisi, Sean F. Monaghan

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