PB1884: ENGAGING INNATE IMMUNITY: A PHASE 1 DOSE ESCALATION STUDY TO ASSESS SAFETY AND TOLERABILITY OF AFM28 MONOTHERAPY IN PATIENTS WITH RELAPSED/REFRACTORY CD123-POSITIVE ACUTE M... by Montserrat Arnan, Pau Montesinos, Stéphane de Botton, Christian Recher, Lydia Wunderle, Michael Emig, Andreas Harstrick, Kerstin Pietzko, Sheena Pinto, Paulien Ravenstijn, Naval Daver

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P714: DISSECTING THE CLINICAL HETEROGENEITY OF ISOLATED TRISOMY 8 MYELODYSPLASTIC SYNDROMES THROUGH MUTATIONAL PROFILE by Sofía María Toribio Castelló, Sandra Castaño, Angela Villaverde-Ramiro, Esperanza Such, Montserrat Arnan, Francesc Solé, Marina Díaz Beyá, María Díez-Campelo, Mónica del Rey, Teresa González, Jesus Hernández Rivas

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DNA methylation profile in chronic myelomonocytic leukemia associates with distinct clinical, biological and genetic features by Laura Palomo, Roberto Malinverni, Marta Cabezón, Blanca Xicoy, Montserrat Arnan, Rosa Coll, Helena Pomares, Olga García, Francisco Fuster-Tormo, Javier Grau, Evarist Feliu, Francesc Solé, Marcus Buschbeck, Lurdes Zamora

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Chronic myelomonocytic leukemia with ring sideroblasts/SF3B1 mutation presents with low monocyte count and resembles myelodysplastic syndromes with-RS/SF3B1 mutation in terms of ph... by Blanca Xicoy, Helena Pomares, Mireia Morgades, Ulrich Germing, Montserrat Arnan, Mar Tormo, Laura Palomo, Elisa Orna, Matteo Della Porta, Felicitas Schulz, Marina Díaz-Beya, Ada Esteban, Antonieta Molero, Luca Lanino, Alejandro Avendaño, Francisca Hernández, Verónica Roldan, Marta Ubezio, Alberto Pineda, María Díez-Campelo, Lurdes Zamora

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R-ESHAP as salvage therapy for patients with relapsed or refractory diffuse large B-cell lymphoma: the influence of prior exposure to rituximab on outcome. A GEL/TAMO study by Alejandro Martín, Eulogio Conde, Montserrat Arnan, Miguel A. Canales, Guillermo Deben, Juan M. Sancho, Rafael Andreu, Antonio Salar, Pedro García-Sanchez, Lourdes Vázquez, Sara Nistal, María-José Requena, Eva M. Donato, José A. González, Ángel León, Concepción Ruiz, Carlos Grande, Eva González-Barca, María-Dolores Caballero

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Survival improvement of patients with FLT3 mutated acute myeloid leukemia: results from a prospective 9 years cohort by Guadalupe Oñate, Marta Pratcorona, Ana Garrido, Alicia Artigas-Baleri, Alex Bataller, Mar Tormo, Montserrat Arnan, Susana Vives, Rosa Coll, Olga Salamero, Ferran Vall-Llovera, Antònia Sampol, Antoni Garcia, Marta Cervera, Sara Garcia Avila, Joan Bargay, Xavier Ortín, Josep F. Nomdedéu, Jordi Esteve, Jorge Sierra, Spanish Cooperative Group for the Study and Treatment of Acute Leukemias and Myelodysplasias (CETLAM)

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Diverse real-life outcomes after intensive risk-adapted therapy for 1034 AML patients from the CETLAM Group by Guadalupe Oñate, Ana Garrido, Montserrat Arnan, Helena Pomares, Ester Alonso, Mar Tormo, Marina Diaz-Beya, Susana Vives, Lurdes Zamora, Antonia Sampol, Rosa Coll, Olga Salamero, Marta Cervera, Antoni Garcia, Ferran Vall-Llovera, Sara Garcia-Avila, Joan Bargay, Xavier Ortin, Eva Iranzo, Francisca Guijarro, Marta Pratcorona, Josep F. Nomdedeu, Jordi Esteve, Jorge Sierra

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Real-life outcome after failure to venetoclax and hypomethylating-based therapy for acute myeloid leukemia by Carlos Jiménez-Vicente, Iago Arribas, Helena Pomares, Guillermo Ramil, Sandra Castaño-Diez, Amanda Isabel Pérez-Valencia, Antonella Luciana Sturla, Mònica López-Guerra, Alexandra Martinez-Roca, Inés Zugasti, Francesca Guijarro, Albert Cortés-Bullich, Beatriz Merchán, Ana Triguero, Inés Monge, Albert Tuca, Guadalupe Oñate, Ana Garrido, Jorge Sierra, Montserrat Arnan, Jordi Esteve, Marina Díaz-Beyá, Spanish CETLAM Group

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P531: MIDOSTAURIN PLUS 7 + 3 OR QUIZARTINIB PLUS 7 + 3 IN FLT3-ITD MUTATED AML by Mar Tormo, Marina Diaz-Beya, Paola Beneit, Ainhoa Fernández Moreno, Montserrat Arnan, Ana Garrido Diaz, Susana Vives, Maria García Fortes, Antonia Sampol, Jorge Labrador, Antonio Garcia-Guiñon, Carmen Botella, Juan Miguel Bergua Burgues, Mayte Olave, Maria Luz Amigo, Xavier Ortín, Ferrand Ferran Vall-Llovera, Maria Pereiro, Josefina Serrano, Maria Jose Sayas Lloris, Almudena De Laiglesia Lorenzo, Juan Jose Bargay Lleonart, Maria Luisa Calabuig Muñoz, Adolfo De La Fuente

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Biological basis of extensive pleiotropy between blood traits and cancer risk by Miguel Angel Pardo-Cea, Xavier Farré, Anna Esteve, Joanna Palade, Roderic Espín, Francesca Mateo, Eric Alsop, Marc Alorda, Natalia Blay, Alexandra Baiges, Arzoo Shabbir, Francesc Comellas, Antonio Gómez, Montserrat Arnan, Alex Teulé, Monica Salinas, Laura Berrocal, Joan Brunet, Paula Rofes, Conxi Lázaro, Miquel Conesa, Juan Jose Rojas, Lars Velten, Wojciech Fendler, Urszula Smyczynska, Dipanjan Chowdhury, Yong Zeng, Housheng Hansen He, Rong Li, Kendall Van Keuren-Jensen, Rafael de Cid, Miquel Angel Pujana

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