Associations between outdoor temperature and bright sunlight with metabolites in two population-based European cohorts by Eveleens Maarse, BC, Loh, NY, Karpe, F, Rosendaal, FR, van Heemst, D, Mook-Kanamori, DO, Willems van Dijk, K, Rensen, PCN, Kooijman, S, Christodoulides, C, Noordam, R

Common variants at 6q22 and 17q21 are associated with intracranial volume by Ikram, M, Fornage, M, Smith, A, Seshadri, S, Schmidt, R, Debette, S, Vrooman, H, Sigurdsson, S, Ropele, S, Taal, H, Mook-Kanamori, DO, Coker, L, Longstreth, W, Niessen, W, Destefano, A, Beiser, A, Zijdenbos, A, Struchalin, M, Jack, C, Rivadeneira, F, Uitterlinden, A, Knopman, D, Hartikainen, A, Pennell, C, Thiering, E

Common variants at 6q22 and 17q21 are associated with intracranial volume. by Ikram, M, Fornage, M, Smith, A, Seshadri, S, Schmidt, R, Debette, S, Vrooman, H, Sigurdsson, S, Ropele, S, Taal, H, Mook-Kanamori, DO, Coker, L, Longstreth, W, Niessen, W, DeStefano, A, Beiser, A, Zijdenbos, A, Struchalin, M, Jack, C, Rivadeneira, F, Uitterlinden, A, Knopman, D, Hartikainen, A, Pennell, C, Thiering, E

New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism. by Horikoshi, M, Yaghootkar, H, Mook-Kanamori, DO, Sovio, U, Taal, H, Hennig, B, Bradfield, J, St Pourcain, B, Evans, D, Charoen, P, Kaakinen, M, Cousminer, D, Lehtimäki, T, Kreiner-Møller, E, Warrington, N, Bustamante, M, Feenstra, B, Berry, D, Thiering, E, Pfab, T, Barton, S, Shields, B, Kerkhof, M, van Leeuwen, E, Fulford, A

Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight. by Freathy, R, Mook-Kanamori, DO, Sovio, U, Prokopenko, I, Timpson, N, Berry, D, Warrington, N, Widen, E, Hottenga, J, Kaakinen, M, Lange, L, Bradfield, J, Kerkhof, M, Marsh, J, Mägi, R, Chen, C, Lyon, H, Kirin, M, Adair, L, Aulchenko, Y, Bennett, A, Borja, J, Bouatia-Naji, N, Charoen, P, Coin, L

Association between common variation at the FTO locus and changes in body mass index from infancy to late childhood: the complex nature of genetic association through growth and de... by Sovio, U, Mook-Kanamori, DO, Warrington, N, Lawrence, R, Briollais, L, Palmer, C, Cecil, J, Sandling, J, Syvänen, A, Kaakinen, M, Beilin, L, Millwood, I, Bennett, A, Laitinen, J, Pouta, A, Molitor, J, Davey Smith, G, Ben-Shlomo, Y, Jaddoe, V, Palmer, L, Pennell, C, Cole, T, McCarthy, M, Järvelin, MR, Timpson, N

A genome-wide association meta-analysis identifies new childhood obesity loci by Bradfield, J, Taal, H, Timpson, N, Scherag, A, Lecoeur, C, Warrington, N, Hypponen, E, Holst, C, Valcarcel, B, Thiering, E, Salem, R, Schumacher, F, Cousminer, D, Sleiman, P, Zhao, J, Berkowitz, R, Vimaleswaran, K, Jarick, I, Pennell, C, Evans, D, St Pourcain, B, Berry, D, Mook-Kanamori, DO, Hofman, A, Rivadeneira, F

Common variants at 12q15 and 12q24 are associated with infant head circumference by Rob Taal, H, St Pourcain, B, Thiering, E, Das, S, Mook-Kanamori, DO, Warrington, N, Kaakinen, M, Kreiner-Møller, E, Bradfield, J, Freathy, R, Geller, F, Guxens, M, Cousminer, D, Kerkhof, M, Timpson, N, Ikram, M, Beilin, L, Bønnelykke, K, Buxton, J, Charoen, P, Chawes, B, Eriksson, J, Evans, D, Hofman, A, Kemp, J

Investigating the relationships between unfavourable habitual sleep and metabolomic traits: evidence from multicohort multivariable regression and Mendelian randomization analyses by Bos, MM, Goulding, NJ, Lee, MA, Hofman, A, Bot, M, Pool, R, Vijfhuizen, LS, Zhang, X, Li, C, Mustafa, R, Neville, M, Li-Gao, R, Trompet, S, Beekman, M, Biermasz, NR, Boomsma, DI, de Boer, I, Christodoulides, C, Dehghan, A, Willems van Dijk, K, Ford, I, Ghanbari, M, Heijmans, BT, Ikram, MA, Jukema, JW, Mook-Kanamori, DO, Karpe, F

Higher thyrotropin leads to unfavorable lipid profile and somewhat higher cardiovascular disease risk: evidence from multi-cohort Mendelian randomization and metabolomic profiling. by van Vliet, NA, Bos, MM, Thesing, CS, Chaker, L, Pietzner, M, Houtman, E, Neville, MJ, Li-Gao, R, Trompet, S, Mustafa, R, Ahmadizar, F, Beekman, M, Bot, M, Budde, K, Christodoulides, C, Dehghan, A, Delles, C, Elliott, P, Evangelou, M, Gao, H, Ghanbari, M, van Herwaarden, AE, Ikram, MA, Jaeger, M, Jukema, JW, Karaman, I, Karpe, F, Kloppenburg, M, Meessen, JMTA, Meulenbelt, I, Milaneschi, Y, Mooijaart, SP, Mook-Kanamori, DO, Netea, MG, Netea-Maier, RT, Peeters, RP, Penninx, BWJH, Sattar, N, Slagboom, PE, Suchiman, HED, Völzke, H, Willems van Dijk, K, Noordam, R, van Heemst, D

Causal associations of adiposity and body fat distribution with coronary heart disease, dtroke dubtypes, and type 2 diabetes mellitus: a Mendelian randomization analysis by Dale, CE, Fatemifar, G, Palmer, TM, White, J, Prieto-Merino, D, Zabaneh, D, Engmann, JEL, Shah, T, Wong, A, Warren, HR, McLachlan, S, Trompet, S, Moldovan, M, Morris, RW, Sofat, R, Kumari, M, Hyppönen, E, Jefferis, BJ, Gaunt, TR, Ben-Shlomo, Y, Zhou, A, Gentry-Maharaj, A, Ryan, A, Mutsert, R, Noordam, R, Caulfield, MJ, Jukema, JW, Worrall, BB, Munroe, PB, Menon, U, Power, C, Kuh, D, Lawlor, DA, Humphries, SE, Mook-Kanamori, DO, Sattar, N, Kivimaki, M, Price, JF, Smith, G, Dudbridge, F, Hingorani, AD, Holmes, MV, Casas, JP

Smoking-by-genotype interaction in type 2 diabetes risk and fasting glucose by Wu, P, Rybin, D, Bielak, LF, Feitosa, MF, Franceschini, N, Li, Y, Lu, Y, Marten, J, Musani, SK, Noordam, R, Raghavan, S, Rose, LM, Schwander, K, Smith, AV, Tajuddin, SM, Vojinovic, D, Amin, N, Arnett, DK, Bottinger, EP, Demirkan, A, Florez, JC, Ghanbari, M, Harris, TB, Launer, LJ, Liu, J, Liu, J, Mook-Kanamori, DO, Murray, AD, Nalls, MA, Peyser, PA, Uitterlinden, AG, Voortman, T, Bouchard, C, Chasman, D, Correa, A, de Mutsert, R, Evans, MK, Gudnason, V, Hayward, C, Kao, L, Kardia, SLR, Kooperberg, C, Loos, RJF, Province, MM, Rankinen, T, Redline, S, Ridker, PM, Rotter, JI, Siscovick, D, Smith, BH, van Duijn, C

Identification of a novel proinsulin-associated SNP and demonstration that proinsulin is unlikely to be a causal factor in subclinical vascular remodelling using Mendelian randomis... by Strawbridge, RJ, Silveira, A, Hoed, MD, Gustafsson, S, Luan, J, Rybin, D, Dupuis, J, Li-Gao, R, Kavousi, M, Dehghan, A, Haljas, K, Lahti, J, Gådin, JR, Bäcklund, A, de Faire, U, Gertow, K, Giral, P, Goel, A, Humphries, SE, Kurl, S, Langenberg, C, Lannfelt, LL, Lind, L, Lindgren, CCM, Mannarino, E, Mook-Kanamori, DO, Morris, AP, de Mutsert, R, Rauramaa, R, Saliba-Gustafsson, P, Sennblad, B, Smit, AJ, Syvänen, AC, Tremoli, E, Veglia, F, Zethelius, B, Björck, HM, Eriksson, JG, Hofman, A, Franco, OH, Watkins, H, Jukema, JW, Florez, JC, Wareham, NJ, Meigs, JB, Ingelsson, E, Baldassarre, D, Hamsten, A

Genome-wide characterization of circulating metabolic biomarkers by Karjalainen, MK, Karthikeyan, S, Oliver-Williams, C, Sliz, E, Allara, E, Fung, WT, Surendran, P, Zhang, W, Jousilahti, P, Kristiansson, K, Salomaa, V, Goodwin, M, Hughes, DA, Boehnke, M, Fernandes Silva, L, Yin, X, Mahajan, A, Neville, MJ, van Zuydam, NR, de Mutsert, R, Li-Gao, R, Mook-Kanamori, DO, Demirkan, A, Liu, J, Noordam, R, Trompet, S, Chen, Z, Kartsonaki, C, Li, L, Lin, K, Hagenbeek, FA, Hottenga, JJ, Pool, R, Ikram, MA, van Meurs, J, Haller, T, Milaneschi, Y, Kähönen, M, Mishra, PP, Joshi, PK, Macdonald-Dunlop, E, Mangino, M, Zierer, J, Acar, IE, Hoyng, CB, Lechanteur, YTE, Franke, L, Kurilshikov, A, Zhernakova, A, Beekman, M, Walters, RG, Karpe, F, McCarthy, MI, van Duijn, C, Kettunen, J

Integration of epidemiologic, pharmacologic, genetic and gut microbiome data in a drug-metabolite atlas by Liu, J, Lahousse, L, Nivard, MG, Bot, M, Chen, L, van Klinken, JB, Thesing, CS, Beekman, M, van den Akker, EB, Slieker, RC, Waterham, E, van der Kallen, CJH, de Boer, I, Li-Gao, R, Vojinovic, D, Amin, N, Radjabzadeh, D, Kraaij, R, Alferink, LJM, Murad, SD, Uitterlinden, AG, Willemsen, G, Pool, R, Milaneschi, Y, van Heemst, D, Suchiman, HED, Rutters, F, Elders, PJM, Beulens, JWJ, van der Heijden, AAWA, van Greevenbroek, MJM, Arts, ICW, Onderwater, GLJ, van den Maagdenberg, AMJM, Mook-Kanamori, DO, Hankemeier, T, Terwindt, GM, Stehouwer, CDA, Geleijnse, JM, Hart, LMT, Slagboom, PE, van Dijk, KW, Zhernakova, A, Fu, J, Penninx, BWJH, Boomsma, DI, Demirkan, A, Stricker, BHC, van Duijn, CM

A genome-wide association meta-analysis identifies new childhood obesity loci by Bradfield, J, Taal, H, Timpson, N, Scherag, A, Lecoeur, C, Warrington, N, Hypponen, E, Holst, C, Valcarcel, B, Thiering, E, Salem, R, Schumacher, F, Cousminer, D, Sleiman, P, Zhao, J, Berkowitz, R, Vimaleswaran, K, Jarick, I, Pennell, C, Evans, D, St Pourcain, B, Berry, D, Mook-Kanamori, DO, Hofman, A, Rivadeneira, F, Uitterlinden, A, van Duijn, C, van der Valk, R, de Jongste, J, Postma, D, Boomsma, D, Gauderman, W, Hassanein, M, Lindgren, C, Mägi, R, Boreham, C, Neville, C, Moreno, L, Elliott, P, Pouta, A, Hartikainen, A, Li, M, Raitakari, O, Lehtimäki, T, Eriksson, J, Palotie, A, Dallongeville, J, Das, S, Deloukas, P, McMahon, G, Ring, S, Kemp, J, Buxton, J, Blakemore, A, Bustamante, M, Guxens, M, Hirschhorn, J, Gillman, M, Kreiner-Møller, E, Bisgaard, H, Gilliland, F, Heinrich, J, Wheeler, E, Barroso, I, O'Rahilly, S, Meirhaeghe, A, Sørensen, T, Power, C, Palmer, L, Hinney, A, Widen, E, Farooqi, I, McCarthy, M, Froguel, P, Meyre, D, Hebebrand, J, Jarvelin, MR, Jaddoe, V, Smith, G, Hakonarson, H, Grant, S

Common variants at 12q15 and 12q24 are associated with infant head circumference. by Taal, H, St Pourcain, B, Thiering, E, Das, S, Mook-Kanamori, DO, Warrington, N, Kaakinen, M, Kreiner-Møller, E, Bradfield, J, Freathy, R, Geller, F, Guxens, M, Cousminer, D, Kerkhof, M, Timpson, N, Ikram, M, Beilin, L, Bønnelykke, K, Buxton, J, Charoen, P, Chawes, B, Eriksson, J, Evans, D, Hofman, A, Kemp, J, Kim, C, Klopp, N, Lahti, J, Lye, S, McMahon, G, Mentch, F, Müller-Nurasyid, M, O'Reilly, P, Prokopenko, I, Rivadeneira, F, Steegers, E, Sunyer, J, Tiesler, C, Yaghootkar, H, Breteler, M, Decarli, C, Breteler, M, Debette, S, Fornage, M, Gudnason, V, Launer, L, van der Lugt, A, Mosley, T, Seshadri, S, Smith, A, Vernooij, M, Blakemore, A, Chiavacci, R, Feenstra, B, Fernandez-Banet, J, Grant, S, Hartikainen, A, van der Heijden, A, Iñiguez, C, Lathrop, M, McArdle, W, Mølgaard, A, Newnham, J, Palmer, L, Palotie, A, Pouta, A, Ring, S, Sovio, U, Standl, M, Uitterlinden, A, Wichmann, H, Vissing, N, DeCarli, C, van Duijn, C, McCarthy, M, Koppelman, G, Estivill, X, Hattersley, A, Melbye, M, Bisgaard, H, Pennell, C, Widen, E, Hakonarson, H, Smith, G, Heinrich, J, Jarvelin, MR, Jaddoe, V

Genome-wide trans-ethnic meta-analysis identifies seven genetic loci influencing erythrocyte traits and a role for RBPMS in erythropoiesis by van Rooij, FJ, Qayyum, R, Smith, AV, Zhou, Y, Trompet, S, Tanaka, T, Keller, MF, Chang, LC, Schmidt, H, Yang, ML, Chen, MH, Hayes, J, Johnson, AD, Yanek, LR, Mueller, C, Lange, L, Floyd, JS, Ghanbari, M, Zonderman, AB, Jukema, JW, Hofman, A, van Duijn, CM, Desch, KC, Saba, Y, Ozel, AB, Snively, BM, Wu, JY, Schmidt, R, Fornage, M, Klein, RJ, Fox, CS, Matsuda, K, Kamatani, N, Wild, PS, Stott, DJ, Ford, I, Slagboom, PE, Yang, J, Chu, AY, Lambert, AJ, Uitterlinden, AG, Franco, OH, Hofer, E, Ginsburg, D, Hu, B, Keating, B, Schick, UM, Brody, JA, Li, JZ, Chen, Z, Zeller, T, Guralnik, JM, Chasman, DI, Peters, LL, Kubo, M, Becker, DM, Li, J, Eiriksdottir, G, Rotter, JI, Levy, D, Grossmann, V, Patel, KV, Chen, CH, BioBank Japan Project, Ridker, PM, Tang, H, Launer, LJ, Rice, KM, Li-Gao, R, Ferrucci, L, Evans, MK, Choudhuri, A, Trompouki, E, Abraham, BJ, Yang, S, Takahashi, A, Kamatani, Y, Kooperberg, C, Harris, TB, Jee, SH, Coresh, J, Tsai, FJ, Longo, DL, Chen, YT, Felix, JF, Yang, Q, Psaty, BM, Boerwinkle, E, Becker, LC, Mook-Kanamori, DO, Wilson, JG, Gudnason, V, O'Donnell, CJ, Dehghan, A, Cupples, LA, Nalls, MA, Morris, AP, Okada, Y, Reiner, AP, Zon, LI, Ganesh, SK

Trans-ethnic association study of blood pressure determinants in over 750,000 individuals by Giri, A, Hellwege, JN, Keaton, JM, Park, J, Qiu, C, Warren, HR, Torstenson, ES, Kovesdy, CP, Sun, YV, Wilson, OD, Robinson-Cohen, C, Roumie, CL, Chung, CP, Birdwell, KA, Damrauer, SM, Duvall, SL, Klarin, D, Cho, K, Wang, Y, Evangelou, E, Cabrera, CP, Wain, LV, Shrestha, R, Mautz, BS, Akwo, EA, Sargurupremraj, M, Debette, S, Boehnke, M, Scott, LJ, Luan, J, Zhao, J-H, Willems, SM, Thériault, S, Shah, N, Oldmeadow, C, Almgren, P, Li-Gao, R, Verweij, N, Boutin, TS, Mangino, M, Ntalla, I, Feofanova, E, Surendran, P, Cook, JP, Karthikeyan, S, Lahrouchi, N, Liu, C, Sepúlveda, N, Richardson, TG, Kraja, A, Amouyel, P, Farrall, M, Poulter, NR, Understanding Society Scientific Group, International Consortium For Blood Pressure, Blood Pressure-International Consortium Of Exome Chip Studies, Laakso, M, Zeggini, E, Sever, P, Scott, RA, Langenberg, C, Wareham, NJ, Conen, D, Palmer, CNA, Attia, J, Chasman, DI, Ridker, PM, Melander, O, Mook-Kanamori, DO, Harst, PVD, Cucca, F, Schlessinger, D, Hayward, C, Spector, TD, Jarvelin, M-R, Hennig, BJ, Timpson, NJ, Wei, W-Q, Smith, JC, Xu, Y, Matheny, ME, Siew, EE, Lindgren, C, Herzig, K-H, Dedoussis, G, Denny, JC, Psaty, BM, Howson, JMM, Munroe, PB, Newton-Cheh, C, Caulfield, MJ, Elliott, P, Gaziano, JM, Concato, J, Wilson, PWF, Tsao, PS, Edwards, DR, Susztak, K, Million Veteran Program, O'Donnell, CJ, Hung, AM, Edwards, TL

Meta-analysis of exome array data identifies six novel genetic loci for lung function by Mahajan, A, Jackson, VE, Latourelle, JC, Wain, LV, Smith, AV, Grove, ML, Bartz, TM, Obeidat, M, Province, MA, Gao, W, Qaiser, B, Porteous, DJ, Cassano, PA, Ahluwalia, TS, Grarup, N, Li, J, Altmaier, E, Marten, J, Harris, SE, Manichaikul, A, Pottinger, TD, Li-Gao, R, Lind-Thomsen, A, Lahousse, L, Imboden, M, Teumer, A, Prins, B, Lyytikäinen, L-P, Eiriksdottir, G, Franceschini, N, Sitlani, CM, Brody, JA, Bossé, Y, Timens, W, Kraja, A, Loukola, A, Tang, W, Liu, Y, Bork-Jensen, J, Justesen, JM, Linneberg, A, Lange, LA, Rawal, R, Karrasch, S, Huffman, JE, Smith, BH, Davies, G, Burkart, KM, Mychaleckyj, JC, Bonten, TN, Enroth, S, Lind, L, Brusselle, GG, Kumar, A, Stubbe, B, Understanding Society Scientific Group, Kähönen, M, Wyss, AB, Psaty, BM, Heckbert, SR, Hao, K, Rantanen, T, Kritchevsky, SB, Lohman, K, Skaaby, T, Pisinger, C, Hansen, T, Schulz, H, Polasek, O, Campbell, A, Starr, JM, Rich, SS, Mook-Kanamori, DO, Johansson, Å, Ingelsson, E, Uitterlinden, AG, Weiss, S, Raitakari, OT, Gudnason, V, North, KE, Gharib, SA, Sin, DD, Taylor, KD, O'Connor, GT, Kaprio, J, Harris, TB, Pederson, O, Vestergaard, H, Wilson, JG, Strauch, K, Hayward, C, Kerr, S, Deary, IJ, Barr, RG, De Mutsert, R, Gyllensten, U, Morris, AP, Ikram, MA, Probst-Hensch, N, Gläser, S, Zeggini, E, Lehtimäki, T, Strachan, DP, Dupuis, J, Morrison, AC, Hall, IP, Tobin, MD, London, SJ