Showing 1 - 17 results of 17 for search 'Moritz J. Frech', query time: 0.05s Refine Results
  1. 1
    Impact of Organelle Transport Deficits on Mitophagy and Autophagy in Niemann–Pick Disease Type C

    Impact of Organelle Transport Deficits on Mitophagy and Autophagy in Niemann–Pick Disease Type C by Maik Liedtke, Christin Völkner, Andreas Hermann, Moritz J. Frech

    Published 2022-02-01
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  2. 2
    Pluripotent Stem Cells for Disease Modeling and Drug Discovery in Niemann-Pick Type C1

    Pluripotent Stem Cells for Disease Modeling and Drug Discovery in Niemann-Pick Type C1 by Christin Völkner, Maik Liedtke, Andreas Hermann, Moritz J. Frech

    Published 2021-01-01
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  3. 3
    Activation of PKC triggers rescue of NPC1 patient specific iPSC derived glial cells from gliosis

    Activation of PKC triggers rescue of NPC1 patient specific iPSC derived glial cells from gliosis by Franziska Peter, Sebastian Rost, Arndt Rolfs, Moritz J. Frech

    Published 2017-08-01
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  4. 4
    Dataset in support of the generation of Niemann-Pick disease Type C1 patient-specific iPS cell lines carrying the novel NPC1 mutation c.1180T>C or the prevalent c.3182T>C mutation – Analysis of pluripotency and neuronal differentiation

    Dataset in support of the generation of Niemann-Pick disease Type C1 patient-specific iPS cell lines carrying the novel NPC1 mutation c.1180T>C or the prevalent c.3182T>C mutation... by Franziska Peter, Michaela Trilck, Michael Rabenstein, Arndt Rolfs, Moritz J. Frech

    Published 2017-06-01
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  5. 5
    Patient-Specific iPSC-Derived Neural Differentiated and Hepatocyte-like Cells, Carrying the Compound Heterozygous Mutation p.V1023Sfs*15/p.G992R, Present the “Variant” Biochemical Phenotype of Niemann-Pick Type C1 Disease

    Patient-Specific iPSC-Derived Neural Differentiated and Hepatocyte-like Cells, Carrying the Compound Heterozygous Mutation p.V1023Sfs*15/p.G992R, Present the “Variant” Biochemical... by Christin Völkner, Maik Liedtke, Robert Untucht, Andreas Hermann, Moritz J. Frech

    Published 2021-11-01
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  6. 6
    Assessment of FDA-Approved Drugs as a Therapeutic Approach for Niemann-Pick Disease Type C1 Using Patient-Specific iPSC-Based Model Systems

    Assessment of FDA-Approved Drugs as a Therapeutic Approach for Niemann-Pick Disease Type C1 Using Patient-Specific iPSC-Based Model Systems by Christin Völkner, Supansa Pantoom, Maik Liedtke, Jan Lukas, Andreas Hermann, Moritz J. Frech

    Published 2022-01-01
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  7. 7
    Oxidative Stress and Alterations in the Antioxidative Defense System in Neuronal Cells Derived from NPC1 Patient-Specific Induced Pluripotent Stem Cells

    Oxidative Stress and Alterations in the Antioxidative Defense System in Neuronal Cells Derived from NPC1 Patient-Specific Induced Pluripotent Stem Cells by Alexandra V. Jürs, Christin Völkner, Maik Liedtke, Katharina Huth, Jan Lukas, Andreas Hermann, Moritz J. Frech

    Published 2020-10-01
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  8. 8
    FUS ALS neurons activate major stress pathways and reduce translation as an early protective mechanism against neurodegeneration

    FUS ALS neurons activate major stress pathways and reduce translation as an early protective mechanism against neurodegeneration by Barbara Szewczyk, René Günther, Julia Japtok, Moritz J. Frech, Marcel Naumann, Hyun O. Lee, Andreas Hermann

    Published 2023-02-01
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  9. 9
    Pathophysiological In Vitro Profile of Neuronal Differentiated Cells Derived from Niemann-Pick Disease Type C2 Patient-Specific iPSCs Carrying the <i>NPC2</i> Mutations c.58G>T/c.140G>T

    Pathophysiological In Vitro Profile of Neuronal Differentiated Cells Derived from Niemann-Pick Disease Type C2 Patient-Specific iPSCs Carrying the <i>NPC2</i> Mutations c.58G>T/c.1... by Maik Liedtke, Christin Völkner, Alexandra V. Jürs, Franziska Peter, Michael Rabenstein, Andreas Hermann, Moritz J. Frech

    Published 2021-04-01
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  10. 10
    Generation of the human iPSC lines AKOSi011-A carrying the mutation p.Pro65Ser/p.Asp35T and AKOSi012-A, carrying the mutation p.Tyr231His, derived from FAHN patient fibroblasts

    Generation of the human iPSC lines AKOSi011-A carrying the mutation p.Pro65Ser/p.Asp35T and AKOSi012-A, carrying the mutation p.Tyr231His, derived from FAHN patient fibroblasts by Fatima Efendic, Saskia Krohn, Hugo Murua Escobar, Sunita Venkateswaran, Steffany A.L. Bennett, Andreas Hermann, Moritz J. Frech

    Published 2023-09-01
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  11. 11
    Generation of the human iPSC line AKOSi010-A from fibroblasts of a female FAHN patient, carrying the compound heterozygous mutation p.Gly45Arg/p.His319Arg

    Generation of the human iPSC line AKOSi010-A from fibroblasts of a female FAHN patient, carrying the compound heterozygous mutation p.Gly45Arg/p.His319Arg by Fatima Efendic, Christin Völkner, Saskia Krohn, Hugo Murua Escobar, Sunita Venkateswaran, Steffany Bennett, Andreas Hermann, Moritz J. Frech

    Published 2022-08-01
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  12. 12
    Generation of two induced pluripotent stem cell lines from a female adult homozygous for the Wilson disease associated ATP7B variant p.H1069Q (AKOSi008-A) and a healthy control (AKOSi009-A)

    Generation of two induced pluripotent stem cell lines from a female adult homozygous for the Wilson disease associated ATP7B variant p.H1069Q (AKOSi008-A) and a healthy control (AK... by Janine Petters, Christin Völkner, Saskia Krohn, Hugo Murua Escobar, Jörn Bullerdiek, Ulrike Reuner, Moritz J. Frech, Andreas Hermann, Jan Lukas

    Published 2020-12-01
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  13. 13
    Generation of an iPSC line (AKOSi004-A) from fibroblasts of a female adult NPC1 patient, carrying the compound heterozygous mutation p.Val1023Serfs*15/p.Gly992Arg and of an iPSC line (AKOSi005-A) from a female adult control individual

    Generation of an iPSC line (AKOSi004-A) from fibroblasts of a female adult NPC1 patient, carrying the compound heterozygous mutation p.Val1023Serfs*15/p.Gly992Arg and of an iPSC li... by Christin Völkner, Maik Liedtke, Janine Petters, Jan Lukas, Hugo Murua Escobar, Gudrun Knuebel, Jörn Bullerdiek, Carsten Holzmann, Andreas Hermann, Moritz J. Frech

    Published 2021-01-01
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  14. 14
    Generation of an iPSC line (AKOSi006-A) from fibroblasts of an NPC1 patient, carrying the homozygous mutation p.I1061T (c.3182 T > C) and a control iPSC line (AKOSi007-A) using a non-integrating Sendai virus system

    Generation of an iPSC line (AKOSi006-A) from fibroblasts of an NPC1 patient, carrying the homozygous mutation p.I1061T (c.3182 T > C) and a control iPSC line (AKOSi007-A) using a n... by Christin Völkner, Maik Liedtke, Janine Petters, Katharina Huth, Gudrun Knuebel, Hugo Murua Escobar, Jörn Bullerdiek, Jan Lukas, Andreas Hermann, Moritz J. Frech

    Published 2020-12-01
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  15. 15
    Generation of the Niemann–Pick type C2 patient-derived iPSC line AKOSi001-A

    Generation of the Niemann–Pick type C2 patient-derived iPSC line AKOSi001-A by Christin Völkner, Franziska Peter, Maik Liedtke, Saskia Krohn, Iris Lindner, Hugo Murua Escobar, Chiara Cimmaruta, Jan Lukas, Andreas Hermann, Moritz J. Frech

    Published 2019-12-01
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  16. 16
    Generation of induced pluripotent stem cell lines AKOSi002-A and AKOSi003-A from symptomatic female adults with Wilson disease

    Generation of induced pluripotent stem cell lines AKOSi002-A and AKOSi003-A from symptomatic female adults with Wilson disease by Janine Petters, Chiara Cimmaruta, Katharina Iwanov, Matthew L. Chang, Christin Völkner, Gudrun Knuebel, Hugo Murua Escobar, Moritz J. Frech, Andreas Hermann, Arndt Rolfs, Jan Lukas

    Published 2020-03-01
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  17. 17
    Identification of Brain-Specific Treatment Effects in NPC1 Disease by Focusing on Cellular and Molecular Changes of Sphingosine-1-Phosphate Metabolism

    Identification of Brain-Specific Treatment Effects in NPC1 Disease by Focusing on Cellular and Molecular Changes of Sphingosine-1-Phosphate Metabolism by Anne Gläser, Franziska Hammerl, Markus H. Gräler, Sina M. Coldewey, Christin Völkner, Moritz J. Frech, Fan Yang, Jiankai Luo, Eric Tönnies, Oliver von Bohlen und Halbach, Nicola Brandt, Diana Heimes, Anna-Maria Neßlauer, Georg Christoph Korenke, Marta Owczarek-Lipska, John Neidhardt, Arndt Rolfs, Andreas Wree, Martin Witt, Anja Ursula Bräuer

    Published 2020-06-01
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