PerTurboID, a targeted in situ method reveals the impact of kinase deletion on its local protein environment in the cytoadhesion complex of malaria-causing parasites ‌ Heledd Davies, Hugo Belda, Malgorzata Broncel, Jill Dalimot, Moritz Treeck

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Time-lapse imaging of red blood cell invasion by the rodent malaria parasite Plasmodium yoelii. ‌ Kazuhide Yahata, Moritz Treeck, Richard Culleton, Tim-Wolf Gilberger, Osamu Kaneko

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Phosphorylation of a Myosin Motor by TgCDPK3 Facilitates Rapid Initiation of Motility during Toxoplasma gondii egress. ‌ Rajshekhar Y Gaji, Derrick E Johnson, Moritz Treeck, Mu Wang, Andy Hudmon, Gustavo Arrizabalaga

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Paracrine rescue of MYR1-deficient Toxoplasma gondii mutants reveals limitations of pooled in vivo CRISPR screens ‌ Francesca Torelli, Diogo M da Fonseca, Simon W Butterworth, Joanna C Young, Moritz Treeck

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PfHDAC1 is an essential regulator of P. falciparum asexual proliferation and host cell invasion genes with a dynamic genomic occupancy responsive to artemisinin stress ‌ Abhishek Kanyal, Bhagyashree Deshmukh, Heledd Davies, D. V. Mamatharani, Dilsha Farheen, Moritz Treeck, Krishanpal Karmodiya

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Toxoplasma gondii sporozoites invade host cells using two novel paralogues of RON2 and AMA1. ‌ Anna Poukchanski, Heather M Fritz, Michelle L Tonkin, Moritz Treeck, Martin J Boulanger, John C Boothroyd

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A 39-Amino-Acid C-Terminal Truncation of GDV1 Disrupts Sexual Commitment in Plasmodium falciparum ‌ Marta Tibúrcio, Eva Hitz, Igor Niederwieser, Gavin Kelly, Heledd Davies, Christian Doerig, Oliver Billker, Till S. Voss, Moritz Treeck

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Protein kinase a dependent phosphorylation of apical membrane antigen 1 plays an important role in erythrocyte invasion by the malaria parasite. ‌ Kerstin Leykauf, Moritz Treeck, Paul R Gilson, Thomas Nebl, Thomas Braulke, Alan F Cowman, Tim W Gilberger, Brendan S Crabb

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A forward genetic screen reveals that calcium-dependent protein kinase 3 regulates egress in Toxoplasma. ‌ Erin Garrison, Moritz Treeck, Emma Ehret, Heidi Butz, Tamila Garbuz, Benji P Oswald, Matt Settles, John Boothroyd, Gustavo Arrizabalaga

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Toxoplasma effector MAF1 mediates recruitment of host mitochondria and impacts the host response. ‌ Lena Pernas, Yaw Adomako-Ankomah, Anjali J Shastri, Sarah E Ewald, Moritz Treeck, Jon P Boyle, John C Boothroyd

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Not a Simple Tether: Binding of <named-content content-type="genus-species">Toxoplasma gondii</named-content> AMA1 to RON2 during Invasion Protects AMA1 from Rhomboid-Mediated Clea... ‌ Shruthi Krishnamurthy, Bin Deng, Roxana del Rio, Kerry R. Buchholz, Moritz Treeck, Siniša Urban, John Boothroyd, Ying-Wai Lam, Gary E. Ward

Ստացեք ամբողջական տեքստը

The calcium-dependent protein kinase 3 of toxoplasma influences basal calcium levels and functions beyond egress as revealed by quantitative phosphoproteome analysis. ‌ Moritz Treeck, John L Sanders, Rajshekhar Y Gaji, Kacie A LaFavers, Matthew A Child, Gustavo Arrizabalaga, Joshua E Elias, John C Boothroyd

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Analysis of CDPK1 targets identifies a trafficking adaptor complex that regulates microneme exocytosis in Toxoplasma ‌ Alex W Chan, Malgorzata Broncel, Eden Yifrach, Nicole R Haseley, Sundeep Chakladar, Elena Andree, Alice L Herneisen, Emily Shortt, Moritz Treeck, Sebastian Lourido

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A positive feedback loop mediates crosstalk between calcium, cyclic nucleotide and lipid signalling in calcium-induced Toxoplasma gondii egress. ‌ Stephanie D Nofal, Caia Dominicus, Malgorzata Broncel, Nicholas J Katris, Helen R Flynn, Gustavo Arrizabalaga, Cyrille Y Botté, Brandon M Invergo, Moritz Treeck

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Differential requirements for cyclase-associated protein (CAP) in actin-dependent processes of Toxoplasma gondii ‌ Alex Hunt, Matthew Robert Geoffrey Russell, Jeanette Wagener, Robyn Kent, Romain Carmeille, Christopher J Peddie, Lucy Collinson, Aoife Heaslip, Gary E Ward, Moritz Treeck

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Expression of the MSPDBL2 antigen in a discrete subset of Plasmodium falciparum schizonts is regulated by GDV1 but may not be linked to sexual commitment ‌ Aline Freville, Lindsay B. Stewart, Kevin K. A. Tetteh, Moritz Treeck, Alfred Cortes, Till S. Voss, Sarah J. Tarr, David A. Baker, David J. Conway

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A CRISPR platform for targeted in vivo screens identifies Toxoplasma gondii virulence factors in mice ‌ Joanna Young, Caia Dominicus, Jeanette Wagener, Simon Butterworth, Xingda Ye, Gavin Kelly, Merav Ordan, Becky Saunders, Rachael Instrell, Michael Howell, Aengus Stewart, Moritz Treeck

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Toxoplasma gondii virulence factor ROP1 reduces parasite susceptibility to murine and human innate immune restriction. ‌ Simon Butterworth, Francesca Torelli, Eloise J Lockyer, Jeanette Wagener, Ok-Ryul Song, Malgorzata Broncel, Matt R G Russell, Aline Cristina A Moreira-Souza, Joanna C Young, Moritz Treeck

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A screen for Plasmodium falciparum sporozoite surface protein binding to human hepatocyte surface receptors identifies novel host–pathogen interactions ‌ Rameswara R. Segireddy, Hugo Belda, Annie S. P. Yang, Kirsten Dundas, Julia Knoeckel, Francis Galaway, Laura Wood, Doris Quinkert, Ellen Knuepfer, Moritz Treeck, Gavin J. Wright, Alexander D. Douglas

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H2A.Z demarcates intergenic regions of the plasmodium falciparum epigenome that are dynamically marked by H3K9ac and H3K4me3. ‌ Richárd Bártfai, Wieteke A M Hoeijmakers, Adriana M Salcedo-Amaya, Arne H Smits, Eva Janssen-Megens, Anita Kaan, Moritz Treeck, Tim-Wolf Gilberger, Kees-Jan Françoijs, Hendrik G Stunnenberg

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