Targeting tyrosine-kinases in ovarian cancer. von Morotti, M, Becker, C, Menada, M, Ferrero, S

Pharmacodynamic and pharmacokinetic markers for anti-angiogenic cancer therapy: Implications for dosing and selection of patients. von Morotti, M, Dass, P, Harris, AL, Lord, SR

Central changes associated with chronic pelvic pain and endometriosis. von Brawn, J, Morotti, M, Zondervan, K, Becker, C, Vincent, K

Peripheral changes in endometriosis-associated pain. von Morotti, M, Vincent, K, Brawn, J, Zondervan, K, Becker, C

Fluciclovine is a potential imaging biomarker of glutamine utilisation in breast cancer von Teoh, EJ, Bridges, EM, Morotti, M, Zois, CE, Lord, SR, Gleeson, FV, Harris, AL

Fluciclovine (F-18) is a marker for high-affinity glutamine transporter ASCT2-mediated amino acid transport in breast cancer von Teoh, E, Morotti, M, Bridges, E, Jones, D, Miar, A, Wigfield, S, Zois, C, Gleeson, F, Harris, A

Single-cell transcriptomics identifies a WNT7A-FZD5 signaling axis that maintains fallopian tube stem cells in patient-derived organoids von Alsaadi, A, Artibani, M, Hu, Z, Wietek, N, Morotti, M, Santana Gonzalez, L, Soleymani Majd, H, Ahmed, A

Increased expression of glutamine transporter SNAT2/SLC38A2 promotes glutamine dependence and oxidative stress resistance, and is associated with worse prognosis in triple-negative... von Morotti, M, Zois, CE, El-Ansari, R, Craze, ML, Rakha, EA, Fan, S-J, Valli, A, Haider, S, Goberdhan, DCI, Green, AR, Harris, AL

Mechanistic drivers of Müllerian duct development and differentiation into the oviduct von Santana Gonzalez, L, Rota, IA, Artibani, M, Morotti, M, Hu, Z, Wietek, N, Alsaadi, A, Albukhari, A, Sauka-Spengler, T, Ahmed, AA, Ahmed, AA

Tumor hypoxia induces nuclear paraspeckle formation through HIF-2α dependent transcriptional activation of NEAT1 leading to cancer cell survival. von Choudhry, H, Albukhari, A, Morotti, M, Hider, S, Moralli, D, Smythies, J, Schödel, J, Green, C, Camps, C, Buffa, F, Ratcliffe, P, Ragoussis, J, Harris, A, Mole, DR

An evolving story of the metastatic voyage of ovarian cancer cells: Cellular and molecular orchestration of the adipose-rich metastatic microenvironment von Motohara, T, Masuda, K, Morotti, M, Zheng, Y, El-Sahhar, S, Yi Chong, K, Wietek, N, Alsaadi, A, Karaminejadranjbar, M, Hu, Z, Artibani, M, Gonzalez, L, Katabuchi, H, Saya, H, Ahmed, A

The BET inhibitor JQ1 selectively impairs tumour response to hypoxia and downregulates CA9 and angiogenesis in triple negative breast cancer (TNBC) von Harris, A, da Motta, L, Ledaki, I, Purshouse, K, Haider, S, De Bastiani, M, Babin, D, Morotti, M, Steers, G, Wigfield, S, Bridges, E, Knapp, S, Ebner, D, Klimt, F, McIntyre, A

Hypoxia-induced switch in SNAT2/SLC38A2 regulation generates endocrine resistance in breast cancer von Morotti, M, Bridges, E, Valli, A, Choudhry, H, Sheldon, H, Wigfield, S, Gray, N, Zois, C, Grimm, F, Jones, D, Teoh, EJ, Wei-Chen, C, Anastasiou, D, Haider, S, McIntyre, A, Goberdhan, DCI, Buffa, F, Harris, AL, Lord, SR

Adaptation to HIF1α deletion in hypoxic cancer cells by upregulation of GLUT14 and creatine metabolism von Valli, A, Morotti, M, Zois, CE, Albers, PK, Soga, T, Feldinger, K, Fischer, R, Frejno, M, McIntyre, A, Bridges, E, Haider, S, Buffa, FM, Baban, D, Rodriguez, M, Yanes, O, Whittington, HJ, Lake, HA, Zervou, S, Lygate, CA, Kessler, BM, Harris, AL

Promises and challenges of adoptive T-cell therapies for solid tumours von Morotti, M, Albukhari, A, Alsaadi, A, Artibani, M, Brenton, JD, Curbishley, SM, Dong, T, Dustin, ML, Hu, Z, McGranahan, N, Miller, ML, Santana-Gonzalez, L, Seymour, L, Shi, T, Van Loo, P, Yau, C, White, H, Wietek, N, Church, DN, Wedge, DC, Ahmed, A

A dynamic CD2 rich compartment at the outer edge of the immunological synapse boosts and integrates signals von Demetriou, P, Abu-Shah, E, Valvo, S, McCuaig, S, Mayya, V, Kvalvaag, A, Starkey, T, Korobchevskaya, K, Lee, LYW, Friedrich, M, Mann, E, Kutuzov, MA, Morotti, M, Wietek, N, Rada, H, Yusuf, S, Afrose, J, Siokis, A, Meyer-Hermann, M, Ahmed, A, Depoil, D, Dustin, ML

The repertoire of serous ovarian cancer non-genetic heterogeneity revealed by single-cell sequencing of normal fallopian tube epithelial cells von Hu, Z, Artibani, M, Alsaadi, A, Wietek, N, Morotti, M, Shi, T, Zhong, Z, Santana Gonzalez, L, El-Sahhar, S, KaramiNejadRanjbar, M, Mallett, G, Feng, Y, Masuda, K, Zheng, Y, Chong, K, Damato, S, Dhar, S, Campo, L, Campanile, R, Soleymani majd, H, Rai, V, Maldonado-Perez, D, Jones, S, Cerundolo, V, Sauka-Spengler, T, Yau, C, Ahmed, AA

Adipocyte-like signature in ovarian cancer minimal residual disease identifies metabolic vulnerabilities of tumor initiating cells von Artibani, M, Masuda, K, Hu, Z, Rauher, PC, Mallett, G, Wietek, N, Morotti, M, Chong, K, KaramiNejadRanjbar, M, Zois, CE, Dhar, S, El-Sahhar, S, Campo, L, Blagden, SP, Damato, S, Pathiraja, PN, Nicum, S, Gleeson, F, Laios, A, Alsaadi, A, Santana Gonzalez, L, Motohara, T, Albukhari, A, Lu, Z, Bast Jr., RC, Harris, AL, Ejsing, CS, Klemm, RW, Yau, C, Sauka-Spengler, T, Ahmed, AA