Development of a Two-Component Nanoparticle Vaccine Displaying an HIV-1 Envelope Glycoprotein that Elicits Tier 2 Neutralising Antibodies by Kegomoditswe Malebo, Jeremy Woodward, Phindile Ximba, Qiniso Mkhize, Sanele Cingo, Thandeka Moyo-Gwete, Penny L. Moore, Anna-Lise Williamson, Rosamund Chapman

Get full text

Dependence on a variable residue limits the breadth of an HIV MPER neutralizing antibody, despite convergent evolution with broadly neutralizing antibodies. by Cathrine Scheepers, Prudence Kgagudi, Nonkululeko Mzindle, Elin S Gray, Thandeka Moyo-Gwete, Bronwen E Lambson, Brent Oosthuysen, Batsirai Mabvakure, Nigel J Garrett, Salim S Abdool Karim, Lynn Morris, Penny L Moore

Get full text

Evaluating the antibody response elicited by diverse HIV envelope immunogens in the African green monkey (Vervet) model by Thandeka Moyo-Gwete, Frances Ayres, Nonkululeko B. Mzindle, Zanele Makhado, Nelia P. Manamela, Simone I. Richardson, Dale Kitchin, Strauss van Graan, Joritha van Heerden, Nishal Parbhoo, Gerald K. Chege, Penny L. Moore

Get full text

Despite delayed kinetics, people living with HIV achieve equivalent antibody function after SARS-CoV-2 infection or vaccination by Boitumelo M. Motsoeneng, Boitumelo M. Motsoeneng, Nelia P. Manamela, Nelia P. Manamela, Haajira Kaldine, Haajira Kaldine, Prudence Kgagudi, Prudence Kgagudi, Tandile Hermanus, Tandile Hermanus, Frances Ayres, Frances Ayres, Zanele Makhado, Zanele Makhado, Thandeka Moyo-Gwete, Thandeka Moyo-Gwete, Mieke A. van der Mescht, Fareed Abdullah, Fareed Abdullah, Michael T. Boswell, Veronica Ueckermann, Theresa M. Rossouw, Shabir A. Madhi, Shabir A. Madhi, Shabir A. Madhi, Penny L. Moore, Penny L. Moore, Penny L. Moore, Simone I. Richardson, Simone I. Richardson

Get full text

Rapid and Successful Implementation of a COVID-19 Convalescent Plasma Programme—The South African Experience by Tanya Nadia Glatt, Caroline Hilton, Cynthia Nyoni, Avril Swarts, Ronel Swanevelder, James Cowley, Cordelia Mmenu, Thandeka Moyo-Gwete, Penny L. Moore, Munzhedzi Kutama, Jabulisile Jaza, Itumeleng Phayane, Tinus Brits, Johan Koekemoer, Ute Jentsch, Derrick Nelson, Karin van den Berg, Marion Vermeulen

Get full text

Population shift in antibody immunity following the emergence of a SARS-CoV-2 variant of concern by Jinal N. Bhiman, Vimbai Sharon Madzorera, Qiniso Mkhize, Cathrine Scheepers, Tandile Hermanus, Frances Ayres, Zanele Makhado, Thandeka Moyo-Gwete, Carol Crowther, Beverley Singh, Mirriam Fortuin, Edmore Marinda, Sean Jooste, Khangelani Zuma, Nompumelelo Zungu, Lynn Morris, Adrian Puren, Leickness Simbayi, Sizulu Moyo, Penny L. Moore

Get full text

Infection pre-Ad26.COV2.S-vaccination primes greater class switching and reduced CXCR5 expression by SARS-CoV-2-specific memory B cells by Robert G. E. Krause, Thandeka Moyo-Gwete, Simone I. Richardson, Zanele Makhado, Nelia P. Manamela, Tandile Hermanus, Nonhlanhla N. Mkhize, Roanne Keeton, Ntombi Benede, Mathilda Mennen, Sango Skelem, Farina Karim, Khadija Khan, Catherine Riou, Ntobeko A. B. Ntusi, Ameena Goga, Glenda Gray, Willem Hanekom, Nigel Garrett, Linda-Gail Bekker, Andreas Groll, Alex Sigal, Penny L. Moore, Wendy A. Burgers, Alasdair Leslie

Get full text

Homologous Ad26.COV2.S vaccination results in reduced boosting of humoral responses in hybrid immunity, but elicits antibodies of similar magnitude regardless of prior infection. by Thandeka Moyo-Gwete, Simone I Richardson, Roanne Keeton, Tandile Hermanus, Holly Spencer, Nelia P Manamela, Frances Ayres, Zanele Makhado, Thopisang Motlou, Marius B Tincho, Ntombi Benede, Amkele Ngomti, Richard Baguma, Masego V Chauke, Mathilda Mennen, Marguerite Adriaanse, Sango Skelem, Ameena Goga, Nigel Garrett, Linda-Gail Bekker, Glenda Gray, Ntobeko A B Ntusi, Catherine Riou, Wendy A Burgers, Penny L Moore

Get full text

Distinct T cell polyfunctional profile in SARS-CoV-2 seronegative children associated with endemic human coronavirus cross-reactivity by Ntombi Benede, Marius B. Tincho, Avril Walters, Vennesa Subbiah, Amkele Ngomti, Richard Baguma, Claire Butters, Lina Hahnle, Mathilda Mennen, Sango Skelem, Marguerite Adriaanse, Heidi Facey-Thomas, Christiaan Scott, Jonathan Day, Timothy F. Spracklen, Strauss van Graan, Sashkia R. Balla, Thandeka Moyo-Gwete, Penny L. Moore, Rae MacGinty, Maresa Botha, Lesley Workman, Marina Johnson, David Goldblatt, Heather J. Zar, Ntobeko A.B. Ntusi, Liesl Zühlke, Kate Webb, Catherine Riou, Wendy A. Burgers, Roanne S. Keeton

Get full text

Safety and immunogenicity of the ChAdOx1 nCoV-19 (AZD1222) vaccine against SARS-CoV-2 in people living with and without HIV in South Africa: an interim analysis of a randomised, do... by Madhi, SA, Koen, AL, Izu, A, Fairlie, L, Cutland, CL, Baillie, V, Padayachee, SD, Dheda, K, Barnabas, SL, Bhorat, QE, Briner, C, Aley, PK, Bhikha, S, Hermanus, T, Horne, E, Jose, A, Kgagudi, P, Lambe, T, Masenya, M, Masilela, M, Mkhize, N, Moultrie, A, Mukendi, CK, Moyo-Gwete, T, Nana, AJ, Nzimande, A, Patel, F, Rhead, S, Taoushanis, C, Thombrayil, A, van Eck, S, Voysey, M, Villafana, TL, Vekemans, J, Gilbert, SC, Pollard, AJ, Moore, PL, Kwatra, G

Safety, effectiveness and immunogenicity of heterologous mRNA-1273 boost after prime with Ad26.COV2.S among healthcare workers in South Africa: The single-arm, open-label, phase 3... by Nigel Garrett, Tarylee Reddy, Nonhlanhla Yende-Zuma, Azwidhwi Takalani, Kubashni Woeber, Annie Bodenstein, Phumeza Jonas, Imke Engelbrecht, Waasila Jassat, Harry Moultrie, Debbie Bradshaw, Ishen Seocharan, Jackline Odhiambo, Kentse Khuto, Simone I Richardson, Millicent A Omondi, Rofhiwa Nesamari, Roanne S Keeton, Catherine Riou, Thandeka Moyo-Gwete, Craig Innes, Zwelethu Zwane, Kathy Mngadi, William Brumskine, Nivashnee Naicker, Disebo Potloane, Sharlaa Badal-Faesen, Steve Innes, Shaun Barnabas, Johan Lombaard, Katherine Gill, Maphoshane Nchabeleng, Elizma Snyman, Friedrich Petrick, Elizabeth Spooner, Logashvari Naidoo, Dishiki Kalonji, Vimla Naicker, Nishanta Singh, Rebone Maboa, Pamela Mda, Daniel Malan, Anusha Nana, Mookho Malahleha, Philip Kotze, Jon J Allagappen, Andreas H Diacon, Gertruida M Kruger, Faeezah Patel, Penny L Moore, Wendy A Burgers, Kate Anteyi, Brett Leav, Linda-Gail Bekker, Glenda E Gray, Ameena Goga, SHERPA study team

Get full text

Safety and immunogenicity of booster vaccination and fractional dosing with Ad26.COV2.S or BNT162b2 in Ad26.COV2.S-vaccinated participants. by Catherine Riou, Jinal N Bhiman, Yashica Ganga, Shobna Sawry, Frances Ayres, Richard Baguma, Sashkia R Balla, Ntombi Benede, Mallory Bernstein, Asiphe S Besethi, Sandile Cele, Carol Crowther, Mrinmayee Dhar, Sohair Geyer, Katherine Gill, Alba Grifoni, Tandile Hermanus, Haajira Kaldine, Roanne S Keeton, Prudence Kgagudi, Khadija Khan, Erica Lazarus, Jean Le Roux, Gila Lustig, Mashudu Madzivhandila, Siyabulela F J Magugu, Zanele Makhado, Nelia P Manamela, Qiniso Mkhize, Paballo Mosala, Thopisang P Motlou, Hygon Mutavhatsindi, Nonkululeko B Mzindle, Anusha Nana, Rofhiwa Nesamari, Amkele Ngomti, Anathi A Nkayi, Thandeka P Nkosi, Millicent A Omondi, Ravindre Panchia, Faeezah Patel, Alessandro Sette, Upasna Singh, Strauss van Graan, Elizabeth M Venter, Avril Walters, Thandeka Moyo-Gwete, Simone I Richardson, Nigel Garrett, Helen Rees, Linda-Gail Bekker, Glenda Gray, Wendy A Burgers, Alex Sigal, Penny L Moore, Lee Fairlie

Get full text