Showing 1 - 8 results of 8 for search 'Mudra Hegde', query time: 0.04s Refine Results
  1. 1
    Uncoupling of sgRNAs from their associated barcodes during PCR amplification of combinatorial CRISPR screens.

    Uncoupling of sgRNAs from their associated barcodes during PCR amplification of combinatorial CRISPR screens. by Mudra Hegde, Christine Strand, Ruth E Hanna, John G Doench

    Published 2018-01-01
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  2. 2
    Accounting for small variations in the tracrRNA sequence improves sgRNA activity predictions for CRISPR screening

    Accounting for small variations in the tracrRNA sequence improves sgRNA activity predictions for CRISPR screening by Peter C. DeWeirdt, Abby V. McGee, Fengyi Zheng, Ifunanya Nwolah, Mudra Hegde, John G. Doench

    Published 2022-09-01
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  3. 3
    Creation of Novel Protein Variants with CRISPR/Cas9-Mediated Mutagenesis: Turning a Screening By-Product into a Discovery Tool.

    Creation of Novel Protein Variants with CRISPR/Cas9-Mediated Mutagenesis: Turning a Screening By-Product into a Discovery Tool. by Katherine F Donovan, Mudra Hegde, Meagan Sullender, Emma W Vaimberg, Cory M Johannessen, David E Root, John G Doench

    Published 2017-01-01
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  4. 4
    Genetic screens in isogenic mammalian cell lines without single cell cloning

    Genetic screens in isogenic mammalian cell lines without single cell cloning by Peter C. DeWeirdt, Annabel K. Sangree, Ruth E. Hanna, Kendall R. Sanson, Mudra Hegde, Christine Strand, Nicole S. Persky, John G. Doench

    Published 2020-02-01
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  5. 5
    Benchmarking of SpCas9 variants enables deeper base editor screens of BRCA1 and BCL2

    Benchmarking of SpCas9 variants enables deeper base editor screens of BRCA1 and BCL2 by Annabel K. Sangree, Audrey L. Griffith, Zsofia M. Szegletes, Priyanka Roy, Peter C. DeWeirdt, Mudra Hegde, Abby V. McGee, Ruth E. Hanna, John G. Doench

    Published 2022-03-01
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  6. 6
    Optimized libraries for CRISPR-Cas9 genetic screens with multiple modalities

    Optimized libraries for CRISPR-Cas9 genetic screens with multiple modalities by Kendall R. Sanson, Ruth E. Hanna, Mudra Hegde, Katherine F. Donovan, Christine Strand, Meagan E. Sullender, Emma W. Vaimberg, Amy Goodale, David E. Root, Federica Piccioni, John G. Doench

    Published 2018-12-01
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  7. 7
    Chromatin complex dependencies reveal targeting opportunities in leukemia

    Chromatin complex dependencies reveal targeting opportunities in leukemia by Fadi J. Najm, Peter DeWeirdt, Molly M. Moore, Samantha M. Bevill, Chadi A. El Farran, Kevin A. Macias, Mudra Hegde, Amanda L. Waterbury, Brian B. Liau, Peter van Galen, John G. Doench, Bradley E. Bernstein

    Published 2023-01-01
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  8. 8
    Scanning mutagenesis of the voltage-gated sodium channel NaV1.2 using base editing

    Scanning mutagenesis of the voltage-gated sodium channel NaV1.2 using base editing by Juan Lorenzo B. Pablo, Savannah L. Cornett, Lei A. Wang, Sooyeon Jo, Tobias Brünger, Nikita Budnik, Mudra Hegde, Jean-Marc DeKeyser, Christopher H. Thompson, John G. Doench, Dennis Lal, Alfred L. George, Jr., Jen Q. Pan

    Published 2023-06-01
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