Genetic and real-world clinical data, combined with empirical validation, nominate Jak-Stat signaling as a target for Alzheimer’s disease therapeutic development by Nevado-Holgado, A, Ribe, E, Thei, L, Furlong, L, Mayer, M, Quan, J, Richardson, J, Cavanagh, J, NIMA Consortium, Lovestone, S

Genetic and Real-World Clinical Data, Combined with Empirical Validation, Nominate Jak-Stat Signaling as a Target for Alzheimer’s Disease Therapeutic Development by Alejo J. Nevado-Holgado, Elena Ribe, Laura Thei, Laura Furlong, Miguel-Angel Mayer, Jie Quan, Jill C. Richardson, Jonathan Cavanagh, NIMA Consortium, Simon Lovestone

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Pharmacological modulation of TSPO in microglia/macrophages and neurons in a chronic neurodegenerative model of prion disease by Marta Vicente-Rodríguez, Renzo Mancuso, Alba Peris-Yague, Camilla Simmons, NIMA Consortium, Diego Gómez-Nicola, V. Hugh Perry, Federico Turkheimer, Simon Lovestone, Christine A. Parker, Diana Cash

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No evidence for differential gene expression in major depressive disorder PBMCs, but robust evidence of elevated biological ageing by John J. Cole, Alison McColl, Robin Shaw, Mary-Ellen Lynall, Philip J. Cowen, Peter de Boer, Wayne C. Drevets, Neil Harrison, Carmine Pariante, Linda Pointon, NIMA consortium, Carl Goodyear, Edward Bullmore, Jonathan Cavanagh

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CSF1R inhibitor JNJ-40346527 attenuates microglial proliferation and neurodegeneration in P301S mice by Mancuso, R, Fryatt, G, Cleal, M, Obst, J, Pipi, E, Monzón-Sandoval, J, Ribe, E, Winchester, L, Webber, C, Nevado, A, Jacobs, T, Austin, N, Theunis, C, Grauwen, K, Daniela Ruiz, E, Mudher, A, Vicente-Rodriguez, M, Parker, C, Simmons, C, Cash, D, Richardson, J, Nima Consortium, Jones, D, Lovestone, S, Gómez-Nicola, D, Perry, V

Higher immune-related gene expression in major depression is independent of CRP levels: results from the BIODEP study by Luca Sforzini, Annamaria Cattaneo, Clarissa Ferrari, Lorinda Turner, Nicole Mariani, Daniela Enache, Caitlin Hastings, Giulia Lombardo, Maria A. Nettis, Naghmeh Nikkheslat, Courtney Worrell, Zuzanna Zajkowska, Melisa Kose, Nadia Cattane, Nicola Lopizzo, Monica Mazzelli, Linda Pointon, Philip J. Cowen, Jonathan Cavanagh, Neil A. Harrison, Declan Jones, Wayne C. Drevets, Valeria Mondelli, Edward T. Bullmore, Neuroimmunology of Mood Disorders and Alzheimer’s Disease (NIMA) Consortium, Carmine M. Pariante

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Inflammatory biomarkers in Alzheimer's disease plasma by Morgan, A, Touchard, S, Leckey, C, O'Hagan, C, Nevado-Holgado, A, Nima Consortium, Barkhof, F, Bertram, L, Blin, O, Bos, I, Dobricic, V, Engelborghs, S, Frisoni, G, Frölich, L, Gabel, S, Johannsen, P, Kettunen, P, Kłoszewska, I, Legido-Quigley, C, Lleó, A, Martinez-Lage, P, Mecocci, P, Meersmans, K, Molinuevo, J, Peyratout, G, Popp, J, Richardson, J, Sala, I, Scheltens, P, Streffer, J, Soininen, H, Tainta-Cuezva, M, Teunissen, C, Tsolaki, M, Vandenberghe, R, Visser, P, Vos, S, Wahlund, L, Wallin, A, Westwood, S, Zetterberg, H, Lovestone, S, Morgan, B