Radiation combines with immune checkpoint blockade to enhance T cell priming in a murine model of poorly immunogenic pancreatic cancer by Courtney T. Stump, Kevin Roehle, Nataly Manjarrez Orduno, Stephanie K. Dougan

Get full text

496 Immune cell profiling across solid tumor types by mass cytometry reveals tumor enrichment of PD-1+/LAG-3+ CD8 memory T cells that exhibit tumor-reactive yet dysfunctional featu... by Justin David, Miye Jacques, Bradley Garman, Laurence Menard, Can Jiang, Sherif Daouti, Priyanka Mehta, Mohan Bolisetty, Nataly Manjarrez Orduno

Renal Cell Carcinoma (RCC) Tumors Display Large Expansion of Double Positive (DP) CD4+CD8+ T Cells With Expression of Exhaustion Markers by Laurence C. Menard, Paul Fischer, Bijal Kakrecha, Peter S. Linsley, Erik Wambre, Maochang C. Liu, Blake J. Rust, Deborah Lee, Becky Penhallow, Nataly Manjarrez Orduno, Steven G. Nadler

Get full text

Comprehensive immunophenotyping of solid tumor-infiltrating immune cells reveals the expression characteristics of LAG-3 and its ligands by Bradley Garman, Can Jiang, Sherif Daouti, Sanah Kumar, Priyanka Mehta, Miye K. Jacques, Laurence Menard, Nataly Manjarrez-Orduno, Sonia Dolfi, Piali Mukherjee, Piali Mukherjee, Sharmila Chamling Rai, Ana Lako, Jennifer D. Koenitzer, Justin M. David

Get full text

Circulating T Cell Subpopulations Correlate With Immune Responses at the Tumor Site and Clinical Response to PD1 Inhibition in Non-Small Cell Lung Cancer by Nataly Manjarrez-Orduño, Laurence C. Menard, Selena Kansal, Paul Fischer, Bijal Kakrecha, Can Jiang, Mark Cunningham, Danielle Greenawalt, Vishal Patel, Minghui Yang, Ryan Golhar, Julie A. Carman, Sergey Lezhnin, Hongyue Dai, Paul S. Kayne, Suzanne J. Suchard, Steven H. Bernstein, Steven G. Nadler

Get full text