Insight into the interplay between mitochondria-regulated cell death and energetic metabolism in osteosarcoma by Hong Toan Lai, Nataliia Naumova, Antonin Marchais, Antonin Marchais, Nathalie Gaspar, Nathalie Gaspar, Birgit Geoerger, Birgit Geoerger, Catherine Brenner

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Synergistic Anti-Tumor Effect of Simvastatin Combined to Chemotherapy in Osteosarcoma by Adèle Mangelinck, Nadia Habel, Audrey Mohr, Nathalie Gaspar, Bojana Stefanovska, Olivia Fromigué

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Incorporating individual historical controls and aggregate treatment effect estimates into a Bayesian survival trial: a simulation study by Caroline Brard, Lisa V. Hampson, Nathalie Gaspar, Marie-Cécile Le Deley, Gwénaël Le Teuff

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Systematic review of phase‐I/II trials enrolling refractory and recurrent Ewing sarcoma: Actual knowledge and future directions to optimize the research by Arthur Felix, Pablo Berlanga, Maud Toulmonde, Judith Landman‐Parker, Sarah Dumont, Gilles Vassal, Marie‐Cécile Le Deley, Nathalie Gaspar

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Establishment and characterization of in vivo orthotopic bioluminescent xenograft models from human osteosarcoma cell lines in Swiss nude and NSG mice by Maria Eugenia Marques da Costa, Estelle Daudigeos‐Dubus, Anne Gomez‐Brouchet, Olivia Bawa, Valerie Rouffiac, Massimo Serra, Katia Scotlandi, Conceição Santos, Birgit Geoerger, Nathalie Gaspar

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In-Vitro and In-Vivo Establishment and Characterization of Bioluminescent Orthotopic Chemotherapy-Resistant Human Osteosarcoma Models in NSG Mice by Maria Eugénia Marques da Costa, Antonin Marchais, Anne Gomez-Brouchet, Bastien Job, Noémie Assoun, Estelle Daudigeos-Dubus, Olivia Fromigué, Conceição Santos, Birgit Geoerger, Nathalie Gaspar

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Longitudinal characterization of primary osteosarcoma and derived subcutaneous and orthotopic relapsed patient-derived xenograft models by Maria Eugenia Marques da Costa, Maria Eugenia Marques da Costa, Robin Droit, Pierre Khneisser, Anne Gomez-Brouchet, Tiphaine Adam-de-Beaumais, Marie Nolla, Nicolas Signolles, Jacob Torrejon, Jacob Torrejon, Bérangère Lombard, Damarys Loew, Olivier Ayrault, Olivier Ayrault, Jean-Yves Scoazec, Birgit Geoerger, Birgit Geoerger, Gilles Vassal, Antonin Marchais, Antonin Marchais, Nathalie Gaspar, Nathalie Gaspar

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Together Intra-Tumor Hypoxia and Macrophagic Immunity Are Driven Worst Outcome in Pediatric High-Grade Osteosarcomas by Charlotte Nazon, Marina Pierrevelcin, Thibault Willaume, Benoît Lhermitte, Noelle Weingertner, Antonio Di Marco, Laurent Bund, Florence Vincent, Guillaume Bierry, Anne Gomez-Brouchet, Françoise Redini, Nathalie Gaspar, Monique Dontenwill, Natacha Entz-Werle

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International randomised controlled trial for the treatment of newly diagnosed EWING sarcoma family of tumours – EURO EWING 2012 Protocol by Jennifer Anderton, Veronica Moroz, Perrine Marec-Bérard, Nathalie Gaspar, Valerie Laurence, Javier Martín-Broto, Ana Sastre, Hans Gelderblom, Cormac Owens, Sophie Kaiser, Melissa Fernández-Pinto, Nicola Fenwick, Abigail Evans, Sandra Strauss, Jeremy Whelan, Keith Wheatley, Bernadette Brennan

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Molecular and phenotypic characterisation of paediatric glioma cell lines as models for preclinical drug development. by Dorine A Bax, Suzanne E Little, Nathalie Gaspar, Lara Perryman, Lynley Marshall, Marta Viana-Pereira, Tania A Jones, Richard D Williams, Anita Grigoriadis, Gilles Vassal, Paul Workman, Denise Sheer, Rui M Reis, Andrew D J Pearson, Darren Hargrave, Chris Jones

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European standard clinical practice recommendations for children and adolescents with primary and recurrent osteosarcoma by Roelof van Ewijk, Nikolas Herold, Fredrik Baecklund, Daniel Baumhoer, Kjetil Boye, Nathalie Gaspar, Semi B. Harrabi, Lianne M. Haveman, Stefanie Hecker-Nolting, Laura Hiemcke-Jiwa, Valentine Martin, Cristina Mata Fernández, Emanuela Palmerini, Michiel A.J. van de Sande, Sandra J. Strauss, Stefan S. Bielack, Leo Kager

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Successive Osteosarcoma Relapses after the First Line O2006/Sarcome-09 Trial: What Can We Learn for Further Phase-II Trials? by Eric Thebault, Sophie Piperno-Neumann, Diep Tran, Hélène Pacquement, Perrine Marec-Berard, Cyril Lervat, Marie-Pierre Castex, Morgane Cleirec, Emmanuelle Bompas, Jean-Pierre Vannier, Dominique Plantaz, Laure Saumet, Cecile Verite, Olivier Collard, Claire Pluchart, Claire Briandet, Laure Monard, Laurence Brugieres, Marie-Cécile Le Deley, Nathalie Gaspar

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Patterns of care and outcome of CIC‐rearranged sarcoma patients: A nationwide study of the French sarcoma group by Mehdi Brahmi, Nathalie Gaspar, Justine Gantzer, Maud Toulmonde, Pascaline Boudou‐Rouquette, emmanuelle Bompas, Nelly Firmin, Thibaud Valentin, Mathilde Cancel, Florence Duffaud, Francois Bertucci, Christophe Perrin, Armelle Dufresne, Perrine Marec‐Bérard, Myriam Jean‐Denis, Isabelle Ray‐Coquard, Francois Le Loarer, Gaille Pierron, Franck Tirode, Jean‐Yves Blay, Sarah Watson

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Characterization of Macrophages and Osteoclasts in the Osteosarcoma Tumor Microenvironment at Diagnosis: New Perspective for Osteosarcoma Treatment? by Anne Gomez-Brouchet, Julia Gilhodes, Nathalie Van Acker, Regis Brion, Corinne Bouvier, Pauline Assemat, Nathalie Gaspar, Sebastien Aubert, Jean-Marc Guinebretiere, Beatrice Marie, Frederique Larousserie, Natacha Entz-Werlé, Gonzague De Pinieux, Eric Mascard, Francois Gouin, Pierre Brousset, Marie-Dominique Tabone, Marta Jimenez, Marie-Cecile Le Deley, Jean-Yves Blay, Laurence Brugieres, Sophie Piperno-Neumann, Francoise Rédini

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Management and outcomes of adolescent and young adult sarcoma patients: results from the French nationwide database NETSARC by Pierre Kubicek, Axel Le Cesne, Cyril Lervat, Maud Toulmonde, Christine Chevreau, Florence Duffaud, Louis-Romée Le Nail, Magali Morelle, Nathalie Gaspar, Cécile Vérité, Marie-Pierre Castex, Nicolas Penel, Esma Saada, Sylvain Causeret, François Bertucci, Christophe Perrin, Emmanuelle Bompas, Daniel Orbach, Valérie Laurence, Sophie Piperno-Neumann, Philippe Anract, Maria Rios, Jean-Claude Gentet, Éric Mascard, Stéphanie Pannier, Pascale Blouin, Sébastien Carrère, Loïc Chaigneau, Pauline Soibinet-Oudot, Nadège Corradini, Pascaline Boudou-Rouquette, Jean-Christophe Ruzic, Valérie Lebrun-Ly, Pascale Dubray-Longeras, Sharmini Varatharajah, Céleste Lebbe, Mickaël Ropars, Jean-Emmanuel Kurtz, Cécile Guillemet, Jean-Pierre Lotz, Juliane Berchoud, Grégory Cherrier, Françoise Ducimetière, Claire Chemin, Antoine Italiano, Charles Honoré, Emmanuel Desandes, Jean-Yves Blay, François Gouin, Perrine Marec-Bérard

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Cancer data quality and harmonization in Europe: the experience of the BENCHISTA Project – international benchmarking of childhood cancer survival by stage by Angela Lopez-Cortes, Fabio Didonè, Laura Botta, Lisa L. Hjalgrim, Zsuzsanna Jakab, Adela Cañete Nieto, Charles Stiller, Bernward Zeller, Gemma Gatta, Kathy Pritchard-Jones, The BENCHISTA Project Working Group, Joanne Aitken, Leisa O’Neil, Monika Hack, Ruth Ladenstein, Elizabeth Van Eycken, Nancy Van Damme, Lindsay Frazier, Beatriz De Camargo, Marceli de Oliveira Santos, Zdravka Valerianova, Dobrin Konstantinov, Sumit Gupta, Jason D Pole, Mario Sekerija, Jan Stary, Jaroslav Sterba, Lisa L. Hjalgrim, Jeanette F Winther, Keiu Paapsi, Brigitte Lacour, Emmanuel Desandes, Jacqueline Clavel, Claire Poulalhon, Friederike Erdmann, Eleni T Petridou, Evdoxia Bouka, Zsuzsanna Jakab, Michael Mian, Rocco Galasso, Giuseppe Sampietro, Francesco Vetrano, Milena M Maule, Carlotta Sacerdote, Paola Ballotari, Emilia De Santis, Margherita Ferrante, Rosalia Ragusa, Luca Boni, Magda Rognoni, Rosalba Amodio, Lorenza Boschetti, Francesco Cuccaro, Danila Bruno, Antonio G Russo, Federico Gervasi, Maria L Gambino, Elisabetta Borciani, Maria Michiara, Lucia Mangone, Gianbattista Spagnoli, Stefano Ferretti, Fabio Falcini, Eugenia Spata, Sonia Manasse, Paola Coccia, Francesca Bella, Adele Caldarella, Teresa Intrieri, Tiziana Scuderi, Roberto V Rizzello, Massimo Rugge, Stefano Guzzinati, Deirdre Murray, Tomohiro Matsuda, Kayo Nakata, Miriam J Azzopardi, Aina H Dahlen, Johannesen Tom Børge, Bernward Zeller, Jerzy Kowalczyk, Monika Jedrzejczyk, Gabriela Caldas, Mihaela Bucurenci, Dana Coza, Vesna Zadnik, Arantza Lopez de Munain, Fernando Almela-Vich, Nieves Fuster-Camarena, Ra f a e l Marcos-Gragera, Maria José Sanchez, Nuria Aragones, Raquel Lopez, Maria Dolores Chirlaque, Marcela Guevara, Elena Pardo, Rafael Peris-Bonet, Adela Cañete Nieto, Marià Carulla, Päivi Lähteenmäki, Claudia E Kuehni, Shelagh M Redmond, Henrike Karim-Kos, Charles Stiller, Paul Stacey, Lucy Irvine, Anna Gavin, Deirdre Fitzpatrick, David S Morrison, Karen Smith, Dyfed Wyn Huws, Janet Warlow, Sandra Strauss, Simon Bailey, Adela Canete Nieto, Nathalie Gaspar, Lisa L. Hjalgrim, Filippo Spreafico, Angela Polanco, Riccardo Capocaccia, Andrea Di Cataldo, Meric Klein

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