Neil Brockdorff

Neil Brockdorff at the [[Royal Society]] in London, July 2018 Neil Alexander Steven Brockdorff (born 1958) is a British biochemist who is a Wellcome Trust Principal Research Fellow and professor in the department of biochemistry at the University of Oxford. Brockdorff's research investigates gene and genome regulation in mammalian development. His interests are in the molecular basis of X-inactivation, the process that evolved in mammals to equalise X chromosome gene expression levels in XX females relative to XY males. Provided by Wikipedia
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  1. 1
    Localized accumulation of Xist RNA in X chromosome inactivation

    Localized accumulation of Xist RNA in X chromosome inactivation by Neil Brockdorff

    Published 2019-12-01
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  2. 2
    The PWWP2A Histone Deacetylase Complex Represses Intragenic Spurious Transcription Initiation in mESCs

    The PWWP2A Histone Deacetylase Complex Represses Intragenic Spurious Transcription Initiation in mESCs by Guifeng Wei, Neil Brockdorff, Tianyi Zhang

    Published 2020-11-01
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  3. 3
    Early loss of Xist RNA expression and inactive X chromosome associated chromatin modification in developing primordial germ cells.

    Early loss of Xist RNA expression and inactive X chromosome associated chromatin modification in developing primordial germ cells. by Mariana de Napoles, Tatyana Nesterova, Neil Brockdorff

    Published 2007-09-01
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  4. 4
    The role of the Xist 5’ m6A region and RBM15 in X chromosome inactivation [version 1; peer review: 1 approved, 2 approved with reservations]

    The role of the Xist 5’ m6A region and RBM15 in X chromosome inactivation [version 1; peer review: 1 approved, 2 approved with reservations] by Heather Coker, Guifeng Wei, Benoit Moindrot, Shabaz Mohammed, Tatyana Nesterova, Neil Brockdorff

    Published 2020-02-01
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  5. 5
    Chromatin sampling--an emerging perspective on targeting polycomb repressor proteins.

    Chromatin sampling--an emerging perspective on targeting polycomb repressor proteins. by Robert J Klose, Sarah Cooper, Anca M Farcas, Neil P Blackledge, Neil Brockdorff

    Published 2013-01-01
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  6. 6
    Transcription initiation activity sets replication origin efficiency in mammalian cells.

    Transcription initiation activity sets replication origin efficiency in mammalian cells. by Joana Sequeira-Mendes, Ramón Díaz-Uriarte, Anwyn Apedaile, Derek Huntley, Neil Brockdorff, María Gómez

    Published 2009-04-01
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  7. 7
    A Pooled shRNA Screen Identifies Rbm15, Spen, and Wtap as Factors Required for Xist RNA-Mediated Silencing

    A Pooled shRNA Screen Identifies Rbm15, Spen, and Wtap as Factors Required for Xist RNA-Mediated Silencing by Benoit Moindrot, Andrea Cerase, Heather Coker, Osamu Masui, Anne Grijzenhout, Greta Pintacuda, Lothar Schermelleh, Tatyana B. Nesterova, Neil Brockdorff

    Published 2015-07-01
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  8. 8
    A dual origin of the Xist gene from a protein-coding gene and a set of transposable elements.

    A dual origin of the Xist gene from a protein-coding gene and a set of transposable elements. by Eugeny A Elisaphenko, Nikolay N Kolesnikov, Alexander I Shevchenko, Igor B Rogozin, Tatyana B Nesterova, Neil Brockdorff, Suren M Zakian

    Published 2008-06-01
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  9. 9
    A variant NuRD complex containing PWWP2A/B excludes MBD2/3 to regulate transcription at active genes

    A variant NuRD complex containing PWWP2A/B excludes MBD2/3 to regulate transcription at active genes by Tianyi Zhang, Guifeng Wei, Christopher J. Millard, Roman Fischer, Rebecca Konietzny, Benedikt M. Kessler, John W. R. Schwabe, Neil Brockdorff

    Published 2018-09-01
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  10. 10
    Variability of sequence surrounding the Xist gene in rodents suggests taxon-specific regulation of X chromosome inactivation.

    Variability of sequence surrounding the Xist gene in rodents suggests taxon-specific regulation of X chromosome inactivation. by Alexander I Shevchenko, Anastasia A Malakhova, Eugeny A Elisaphenko, Nina A Mazurok, Tatyana B Nesterova, Neil Brockdorff, Suren M Zakian

    Published 2011-01-01
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  11. 11
    Xist-mediated silencing requires additive functions of SPEN and Polycomb together with differentiation-dependent recruitment of SmcHD1

    Xist-mediated silencing requires additive functions of SPEN and Polycomb together with differentiation-dependent recruitment of SmcHD1 by Joseph S. Bowness, Tatyana B. Nesterova, Guifeng Wei, Lisa Rodermund, Mafalda Almeida, Heather Coker, Emma J. Carter, Artun Kadaster, Neil Brockdorff

    Published 2022-05-01
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  12. 12
    Ordered chromatin changes and human X chromosome reactivation by cell fusion-mediated pluripotent reprogramming

    Ordered chromatin changes and human X chromosome reactivation by cell fusion-mediated pluripotent reprogramming by Irene Cantone, Hakan Bagci, Dirk Dormann, Gopuraja Dharmalingam, Tatyana Nesterova, Neil Brockdorff, Claire Rougeulle, Celine Vallot, Edith Heard, Ronan Chaligne, Matthias Merkenschlager, Amanda G. Fisher

    Published 2016-08-01
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  13. 13
    Targeting Polycomb to Pericentric Heterochromatin in Embryonic Stem Cells Reveals a Role for H2AK119u1 in PRC2 Recruitment

    Targeting Polycomb to Pericentric Heterochromatin in Embryonic Stem Cells Reveals a Role for H2AK119u1 in PRC2 Recruitment by Sarah Cooper, Martin Dienstbier, Raihann Hassan, Lothar Schermelleh, Jafar Sharif, Neil P. Blackledge, Valeria De Marco, Sarah Elderkin, Haruhiko Koseki, Robert Klose, Andreas Heger, Neil Brockdorff

    Published 2014-06-01
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  14. 14
    Jarid2 Coordinates Nanog Expression and PCP/Wnt Signaling Required for Efficient ESC Differentiation and Early Embryo Development

    Jarid2 Coordinates Nanog Expression and PCP/Wnt Signaling Required for Efficient ESC Differentiation and Early Embryo Development by David Landeira, Hakan Bagci, Andrzej R. Malinowski, Karen E. Brown, Jorge Soza-Ried, Amelie Feytout, Zoe Webster, Elodie Ndjetehe, Irene Cantone, Helena G. Asenjo, Neil Brockdorff, Thomas Carroll, Matthias Merkenschlager, Amanda G. Fisher

    Published 2015-07-01
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  15. 15
    Systematic allelic analysis defines the interplay of key pathways in X chromosome inactivation

    Systematic allelic analysis defines the interplay of key pathways in X chromosome inactivation by Tatyana B. Nesterova, Guifeng Wei, Heather Coker, Greta Pintacuda, Joseph S. Bowness, Tianyi Zhang, Mafalda Almeida, Bianca Bloechl, Benoit Moindrot, Emma J. Carter, Ines Alvarez Rodrigo, Qi Pan, Ying Bi, Chun-Xiao Song, Neil Brockdorff

    Published 2019-07-01
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  16. 16
    MicroRNAs of the miR-290–295 Family Maintain Bivalency in Mouse Embryonic Stem Cells

    MicroRNAs of the miR-290–295 Family Maintain Bivalency in Mouse Embryonic Stem Cells by Bryony Graham, Antoine Marcais, Gopuraja Dharmalingam, Thomas Carroll, Chryssa Kanellopoulou, Johannes Graumann, Tatyana B. Nesterova, Anna Bermange, Pijus Brazauskas, Barbara Xella, Skirmantas Kriaucionis, Douglas R. Higgs, Neil Brockdorff, Matthias Mann, Amanda G. Fisher, Matthias Merkenschlager

    Published 2016-05-01
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  17. 17
    Considerations when investigating lncRNA function in vivo

    Considerations when investigating lncRNA function in vivo by Andrew R Bassett, Asifa Akhtar, Denise P Barlow, Adrian P Bird, Neil Brockdorff, Denis Duboule, Anne Ephrussi, Anne C Ferguson-Smith, Thomas R Gingeras, Wilfried Haerty, Douglas R Higgs, Eric A Miska, Chris P Ponting

    Published 2014-08-01
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  18. 18
    FGF4 independent derivation of trophoblast stem cells from the common vole.

    FGF4 independent derivation of trophoblast stem cells from the common vole. by Elena V Grigor'eva, Alexander I Shevchenko, Nina A Mazurok, Eugeny A Elisaphenko, Antonina I Zhelezova, Alexander G Shilov, Pavel A Dyban, Andrey P Dyban, Ekaterina M Noniashvili, Sergey Ya Slobodyanyuk, Tatyana B Nesterova, Neil Brockdorff, Suren M Zakian

    Published 2009-09-01
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  19. 19
    KDM2B links the Polycomb Repressive Complex 1 (PRC1) to recognition of CpG islands

    KDM2B links the Polycomb Repressive Complex 1 (PRC1) to recognition of CpG islands by Anca M Farcas, Neil P Blackledge, Ian Sudbery, Hannah K Long, Joanna F McGouran, Nathan R Rose, Sheena Lee, David Sims, Andrea Cerase, Thomas W Sheahan, Haruhiko Koseki, Neil Brockdorff, Chris P Ponting, Benedikt M Kessler, Robert J Klose

    Published 2012-12-01
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  20. 20
    Smchd1 Targeting to the Inactive X Is Dependent on the Xist-HnrnpK-PRC1 Pathway

    Smchd1 Targeting to the Inactive X Is Dependent on the Xist-HnrnpK-PRC1 Pathway by Natasha Jansz, Tatyana Nesterova, Andrew Keniry, Megan Iminitoff, Peter F. Hickey, Greta Pintacuda, Osamu Masui, Simon Kobelke, Niall Geoghegan, Kelsey A. Breslin, Tracy A. Willson, Kelly Rogers, Graham F. Kay, Archa H. Fox, Haruhiko Koseki, Neil Brockdorff, James M. Murphy, Marnie E. Blewitt

    Published 2018-11-01
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