FROM BENIGN TO MALIGNANT DISEASE by Niccolò Bolli

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The molecular pathogenesis of multiple myeloma by Niccolò Bolli, Giovanni Martinelli, Claudio Cerchione

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A Journey Through Myeloma Evolution: From the Normal Plasma Cell to Disease Complexity by Matteo C. Da Vià, Bachisio Ziccheddu, Akihiro Maeda, Filippo Bagnoli, Giulia Perrone, Niccolò Bolli

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DIS3 mutations in multiple myeloma impact the transcriptional signature and clinical outcome by Katia Todoerti, Domenica Ronchetti, Vanessa Favasuli, Francesco Maura, Fortunato Morabito, Niccolò Bolli, Elisa Taiana, Antonino Neri

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Expression levels of NONO, a nuclear protein primarily involved in paraspeckles function, are associated with several deregulated molecular pathways and poor clinical outcome in mu... by Domenica Ronchetti, Vanessa Katia Favasuli, Ilaria Silvestris, Katia Todoerti, Federica Torricelli, Niccolò Bolli, Alessia Ciarrocchi, Elisa Taiana, Antonino Neri

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Translocations and mutations involving the nucleophosmin (NPM1) gene in lymphomas and leukemias by Brunangelo Falini, Ildo Nicoletti, Niccolò Bolli, Maria Paola Martelli, Arcangelo Liso, Paolo Gorello, Franco Mandelli, Cristina Mecucci, Massimo Fabrizio Martelli

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Unraveling the Neurological Complexity of Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal Protein, and Skin Changes Syndrome: A Report of a Challenging Case of a Young Wom... by Gioconda Furciniti, Giuseppe Casalino, Francesco M. Lo Russo, Niccolò Bolli, Megi Meneri, Giacomo P. Comi, Stefania P. Corti, Daniele Velardo

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Limits and Applications of Genomic Analysis of Circulating Tumor DNA as a Liquid Biopsy in Asymptomatic Forms of Multiple Myeloma by Martina Manzoni, Alessandra Pompa, Sonia Fabris, Francesca Pelizzoni, Gabriella Ciceri, Manuela Seia, Bachisio Ziccheddu, Niccolò Bolli, Paolo Corradini, Luca Baldini, Antonino Neri, Marta Lionetti

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Cytoplasmic mutated nucleophosmin is stable in primary leukemic cells and in a xenotransplant model of NPMc+ acute myeloid leukemia in SCID mice by Brunangelo Falini, Maria Paola Martelli, Cristina Mecucci, Arcangelo Liso, Niccolò Bolli, Barbara Bigerna, Alessandra Pucciarini, Stefano Pileri, Giovanna Meloni, Massimo F. Martelli, Torsten Haferlach, Susanne Schnittger

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TENT5C/FAM46C modulation <i>in vivo</i> reveals a trade-off between antibody secretion and tumor growth in multiple myeloma by Massimo Resnati, Sara Pennacchio, Lisa Viviani, Tommaso Perini, Maria Materozzi, Ugo Orfanelli, Jessica Bordini, Raffaella Molteni, Mario Nuvolone, Matteo Da Vià, Francesca Lazzaroni, Niccolò Bolli, Simone Cenci, Enrico Milan

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P847: BIOLOGICAL AND MOLECULAR CHARACTERIZATION OF IN SILICO IDENTIFIED PUTATIVE INHIBITORS OF PARASPECKLE ASSEMBLY WITH POTENTIAL ANTI-MULTIPLE MYELOMA ACTIVITY. by Valentina Traini, Giuseppina Fabbiano, Domenica Ronchetti, Ilaria Silvestris, Vanessa Katia Favasuli, Silvia Erratico, Domenica Giannandrea, Tommaso Laurenzi, Luca Palazzolo, Yvan Torrente, Raffaella Chiaramonte, Ivano Eberini, Niccolò Bolli, Antonino Neri, Elisa Taiana

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Activation of long non-coding RNA NEAT1 leads to survival advantage of multiple myeloma cells by supporting a positive regulatory loop with DNA repair proteins by Elisa Taiana, Cecilia Bandini, Vanessa Katia Favasuli, Domenica Ronchetti, Ilaria Silvestris, Noemi Puccio, Katia Todoerti, Silvia Erratico, Domenica Giannandrea, Niccolò Bolli, Nicola Amodio, Alessia Ciarrocchi, Raffaella Chiaramonte, Yvan Torrente, Roberto Piva, Antonino Neri

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Clinical, Morphological and Clonal Progression of VEXAS Syndrome in the Context of Myelodysplasia Treated with Azacytidine by Marco Manzoni, Alessandro Bosi, Sonia Fabris, Marta Lionetti, Simone Salerio, Anna Chiara Migliorini, Francesca Cavallaro, Kordelia Barbullushi, Nicolò Rampi, Vittorio Montefusco, Maria Grazia Alessio, Antonino Neri, Luca Baldini, Mariarita Sciumè, Elena Tagliaferri, Nicola Fracchiolla, Niccolò Bolli

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Mutations in the alternative complement pathway in multiple myeloma patients with carfilzomib-induced thrombotic microangiopathy by Maria Moscvin, Christine Ivy Liacos, Tianzeng Chen, Foteini Theodorakakou, Despina Fotiou, Shahrier Hossain, Sean Rowell, Houry Leblebjian, Eileen Regan, Peter Czarnecki, Filippo Bagnoli, Niccolo’ Bolli, Paul Richardson, Helmut G. Rennke, Meletios A. Dimopoulos, Efstathios Kastritis, Giada Bianchi

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Genomic and immune determinants of resistance to daratumumab-based therapy in relapsed refractory multiple myeloma by Bachisio Ziccheddu, Claudia Giannotta, Mattia D’Agostino, Giuseppe Bertuglia, Elona Saraci, Stefania Oliva, Elisa Genuardi, Marios Papadimitriou, Benjamin Diamond, Paolo Corradini, David Coffey, Ola Landgren, Niccolò Bolli, Benedetto Bruno, Mario Boccadoro, Massimo Massaia, Francesco Maura, Alessandra Larocca

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Combinatorial strategies targeting NEAT1 and AURKA as new potential therapeutic options for multiple myeloma by Noemi Puccio, Gloria Manzotti, Elisabetta Mereu, Federica Torricelli, Domenica Ronchetti, Michela Cumerlato, Ilaria Craparotta, Laura Di Rito, Marco Bolis, Valentina Traini, Veronica Manicardi, Valentina Fragliasso, Yvan Torrente, Nicola Amodio, Niccolò Bolli, Elisa Taiana, Alessia Ciarrochi, Roberto Piva, Antonino Neri

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Characterization of gene mutations and copy number changes in acute myeloid leukemia using a rapid target enrichment protocol by Niccolò Bolli, Nicla Manes, Thomas McKerrell, Jianxiang Chi, Naomi Park, Gunes Gundem, Michael A. Quail, Vijitha Sathiaseelan, Bram Herman, Charles Crawley, Jenny I. O. Craig, Natalie Conte, Carolyn Grove, Elli Papaemmanuil, Peter J. Campbell, Ignacio Varela, Paul Costeas, George S. Vassiliou

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<i>DIS3</i> depletion in multiple myeloma causes extensive perturbation in cell cycle progression and centrosome amplification by Vanessa K. Favasuli, Domenica Ronchetti, Ilaria Silvestris, Noemi Puccio, Giuseppina Fabbiano, Valentina Traini, Katia Todoerti, Silvia Erratico, Alessia Ciarrocchi, Valentina Fragliasso, Domenica Giannandrea, Francesca Tumiatti, Raffaella Chiaramonte, Yvan Torrente, Palma Finelli, Eugenio Morelli, Nikhil C. Munshi, Niccolò Bolli, Antonino Neri, Elisa Taìana

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<i>CDKN2A</i> deletion is a frequent event associated with poor outcome in patients with peripheral T-cell lymphoma not otherwise specified (PTCL-NOS) by Francesco Maura, Anna Dodero, Cristiana Carniti, Niccolò Bolli, Martina Magni, Valentina Monti, Antonello Cabras, Daniel Leongamornlert, Federico Abascal, Benjamin Diamond, Bernardo Rodriguez-Martin, Jorge Zamora, Adam Butler, Inigo Martincorena, Jose M. C. Tubio, Peter J. Campbell, Annalisa Chiappella, Giancarlo Pruneri, Paolo Corradini

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A one-mutation mathematical model can explain the age incidence of acute myeloid leukemia with mutated nucleophosmin (NPM1) by Arcangelo Liso, Filippo Castiglione, Antonio Cappuccio, Fabrizio Stracci, Richard F. Schlenk, Sergio Amadori, Christian Thiede, Susanne Schnittger, Peter J.M. Valk, Konstanze Döhner, Massimo F. Martelli, Markus Schaich, Jürgen Krauter, Arnold Ganser, Maria P. Martelli, Niccolò Bolli, Bob Löwenberg, Torsten Haferlach, Gerhard Ehninger, Franco Mandelli, Hartmut Döhner, Franziska Michor, Brunangelo Falini

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