Metabolomics paves the way for improved drug target identification by Belinda B Garana, Nicholas A Graham

Get full text

Drug mechanism enrichment analysis improves prioritization of therapeutics for repurposing by Belinda B. Garana, James H. Joly, Alireza Delfarah, Hyunjun Hong, Nicholas A. Graham

Get full text

Kinetic and data-driven modeling of pancreatic β-cell central carbon metabolism and insulin secretion. by Patrick E Gelbach, Dongqing Zheng, Scott E Fraser, Kate L White, Nicholas A Graham, Stacey D Finley

Get full text

Functional and phosphoproteomic analysis of β-adrenergic receptor signaling at excitatory synapses in the CA1 region of the ventral hippocampus by Shekib A. Jami, Brent J. Wilkinson, Ryan Guglietta, Nicolas Hartel, Walter E. Babiec, Nicholas A. Graham, Marcelo P. Coba, Thomas J. O’Dell

Get full text

Glucose deprivation activates a metabolic and signaling amplification loop leading to cell death by Nicholas A Graham, Martik Tahmasian, Bitika Kohli, Evangelia Komisopoulou, Maggie Zhu, Igor Vivanco, Michael A Teitell, Hong Wu, Antoni Ribas, Roger S Lo, Ingo K Mellinghoff, Paul S Mischel, Thomas G Graeber

Get full text

Merging metabolic modeling and imaging for screening therapeutic targets in colorectal cancer by Niki Tavakoli, Emma J. Fong, Abigail Coleman, Yu-Kai Huang, Mathias Bigger, Michael E. Doche, Seungil Kim, Heinz-Josef Lenz, Nicholas A. Graham, Paul Macklin, Stacey D. Finley, Shannon M. Mumenthaler

Get full text

MOTS-c is an exercise-induced mitochondrial-encoded regulator of age-dependent physical decline and muscle homeostasis by Joseph C. Reynolds, Rochelle W. Lai, Jonathan S. T. Woodhead, James H. Joly, Cameron J. Mitchell, David Cameron-Smith, Ryan Lu, Pinchas Cohen, Nicholas A. Graham, Bérénice A. Benayoun, Troy L. Merry, Changhan Lee

Get full text

Mutations in the postsynaptic density signaling hub TNIK disrupt PSD signaling in human models of neurodevelopmental disorders by Jianzhi Jiang, Brent Wilkinson, Ilse Flores, Nicolas Hartel, Simeon R. Mihaylov, Veronica A. Clementel, Helen R. Flynn, Fowsan S. Alkuraya, Sila Ultanir, Nicholas A. Graham, Marcelo P. Coba, Marcelo P. Coba, Marcelo P. Coba

Get full text

Bladder cancer cells shift rapidly and spontaneously to cisplatin-resistant oxidative phosphorylation that is trackable in real time by Tong Xu, Jason A. Junge, Alireza Delfarah, Yi-Tsung Lu, Cosimo Arnesano, Maheen Iqbal, Kevin Delijani, Tien-Chan Hsieh, Emmanuelle Hodara, Hemal H. Mehta, Pinchas Cohen, Nicholas A. Graham, Scott E. Fraser, Amir Goldkorn

Get full text

The CARM1 transcriptome and arginine methylproteome mediate skeletal muscle integrative biology by Tiffany L. vanLieshout, Derek W. Stouth, Nicolas G. Hartel, Goutham Vasam, Sean Y. Ng, Erin K. Webb, Irena A. Rebalka, Andrew I. Mikhail, Nicholas A. Graham, Keir J. Menzies, Thomas J. Hawke, Vladimir Ljubicic

Get full text

Recurrent patterns of DNA copy number alterations in tumors reflect metabolic selection pressures by Nicholas A Graham, Aspram Minasyan, Anastasia Lomova, Ashley Cass, Nikolas G Balanis, Michael Friedman, Shawna Chan, Sophie Zhao, Adrian Delgado, James Go, Lillie Beck, Christian Hurtz, Carina Ng, Rong Qiao, Johanna ten Hoeve, Nicolaos Palaskas, Hong Wu, Markus Müschen, Asha S Multani, Elisa Port, Steven M Larson, Nikolaus Schultz, Daniel Braas, Heather R Christofk, Ingo K Mellinghoff, Thomas G Graeber

Get full text