Regulation of Murine Natural Killer Cell Commitment 由 Nicholas D Huntington, Stephen L Nutt, Sebastian eCarotta

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1538 Cytokine checkpoint discovery in human NK cells 由 Nicholas D Huntington, Iva Nikolic, Joe Cursons, Benjamin Shields, Stephane Chappaz

Soluble CD52 mediates immune suppression by human seminal fluid 由 Leonard C. Harrison, Leonard C. Harrison, Natalie L. Stone, Natalie L. Stone, Esther Bandala-Sanchez, Esther Bandala-Sanchez, Nicholas D. Huntington, Nicholas D. Huntington, Robert I. McLachlan, Jai Rautela, Jai Rautela, Moira K. O’Bryan

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Crosstalk Between Gut Microbiota and Innate Immunity and Its Implication in Autoimmune Diseases 由 Yuhao Jiao, Yuhao Jiao, Li Wu, Li Wu, Li Wu, Nicholas D. Huntington, Xuan Zhang, Xuan Zhang

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Loss-of-Function in SMAD4 Might Not Be Critical for Human Natural Killer Cell Responsiveness to TGF-β 由 Lachlan P. Healy, Lachlan P. Healy, Gustavo R. Rossi, Gustavo R. Rossi, Jai Rautela, Charlotte A. Slade, Charlotte A. Slade, Charlotte A. Slade, Nicholas D. Huntington, Nicholas D. Huntington, Ingrid M. Winship, Ingrid M. Winship, Fernando Souza-Fonseca-Guimaraes, Fernando Souza-Fonseca-Guimaraes

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Rapid Inflammation in Mice Lacking Both SOCS1 and SOCS3 in Hematopoietic Cells. 由 Takashi Ushiki, Nicholas D Huntington, Stefan P Glaser, Hiu Kiu, Angela Georgiou, Jian-Guo Zhang, Donald Metcalf, Nicos A Nicola, Andrew W Roberts, Warren S Alexander

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Optimisation of a primary human CAR‐NK cell manufacturing pipeline 由 Aline Pfefferle, Julian Contet, Kahlia Wong, Charlotte Chen, Els Verhoeyen, Chloe K Slichter, Kimberly S Schluns, Joseph Cursons, Richard Berry, Iva Nikolic, Jai Rautela, Nicholas D Huntington

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DOT1L maintains NK cell phenotype and function for optimal tumor control 由 Harrison Sudholz, Iona S. Schuster, Momeneh Foroutan, Xavier Sng, Christopher E. Andoniou, Anh Doan, Tania Camilleri, Zihan Shen, Colby Zaph, Mariapia A. Degli-Esposti, Nicholas D. Huntington, Sebastian Scheer

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Deciphering the Innate Lymphoid Cell Transcriptional Program 由 Cyril Seillet, Lisa A. Mielke, Daniela B. Amann-Zalcenstein, Shian Su, Jerry Gao, Francisca F. Almeida, Wei Shi, Matthew E. Ritchie, Shalin H. Naik, Nicholas D. Huntington, Sebastian Carotta, Gabrielle T. Belz

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A small molecule inhibitor of PTP1B and PTPN2 enhances T cell anti-tumor immunity 由 Shuwei Liang, Eric Tran, Xin Du, Jiajun Dong, Harrison Sudholz, Hao Chen, Zihan Qu, Nicholas D. Huntington, Jeffrey J. Babon, Nadia J. Kershaw, Zhong-Yin Zhang, Jonathan B. Baell, Florian Wiede, Tony Tiganis

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Cord Blood CD8+ T Cells Have a Natural Propensity to Express IL-4 in a Fatty Acid Metabolism and Caspase Activation-Dependent Manner 由 Yuxia Zhang, Yuxia Zhang, Yuxia Zhang, Jovana Maksimovic, Jovana Maksimovic, Bing Huang, David Peter De Souza, David Peter De Souza, Gaetano Naselli, Gaetano Naselli, Huan Chen, Li Zhang, Kai Weng, Hanquan Liang, Yanhui Xu, Yanhui Xu, John M. Wentworth, John M. Wentworth, Nicholas D. Huntington, Nicholas D. Huntington, Alicia Oshlack, Alicia Oshlack, Sitang Gong, Axel Kallies, Axel Kallies, Peter Vuillermin, Peter Vuillermin, Peter Vuillermin, Peter Vuillermin, Min Yang, Leonard C. Harrison, Leonard C. Harrison

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Hhex Directly Represses BIM-Dependent Apoptosis to Promote NK Cell Development and Maintenance 由 Wilford Goh, Sebastian Scheer, Jacob T. Jackson, Soroor Hediyeh-Zadeh, Rebecca B. Delconte, Iona S. Schuster, Christopher E. Andoniou, Jai Rautela, Mariapia A. Degli-Esposti, Melissa J. Davis, Matthew P. McCormack, Stephen L. Nutt, Nicholas D. Huntington

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Context-Dependent Role for T-bet in T Follicular Helper Differentiation and Germinal Center Function following Viral Infection 由 Amania A. Sheikh, Lucy Cooper, Meiqi Feng, Fernando Souza-Fonseca-Guimaraes, Fanny Lafouresse, Brigette C. Duckworth, Nicholas D. Huntington, James J. Moon, Marc Pellegrini, Stephen L. Nutt, Gabrielle T. Belz, Kim L. Good-Jacobson, Joanna R. Groom

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Targeting CISH enhances natural cytotoxicity receptor signaling and reduces NK cell exhaustion to improve solid tumor immunity 由 Eric Vivier, Daniel Olive, Remy Castellano, Els Verhoeyen, Pierre-Louis Bernard, Rebecca Delconte, Sonia Pastor, Vladimir Laletin, Cathy Costa Da Silva, Armelle Goubard, Emmanuelle Josselin, Adrien Krug, Julien Vernerey, Raynier Devillier, Nicholas D Huntington, Jacques Nunes, Geoffrey Guittard

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IL-33-mediated mast cell activation promotes gastric cancer through macrophage mobilization 由 Moritz F. Eissmann, Christine Dijkstra, Andrew Jarnicki, Toby Phesse, Jamina Brunnberg, Ashleigh R. Poh, Nima Etemadi, Evelyn Tsantikos, Stefan Thiem, Nicholas D. Huntington, Margaret L. Hibbs, Alex Boussioutas, Michele A. Grimbaldeston, Michael Buchert, Robert J. J. O’Donoghue, Frederick Masson, Matthias Ernst

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Transcriptome sequencing and multi-plex imaging of prostate cancer microenvironment reveals a dominant role for monocytic cells in progression 由 Stefano Mangiola, Patrick McCoy, Martin Modrak, Fernando Souza-Fonseca-Guimaraes, Daniel Blashki, Ryan Stuchbery, Simon P. Keam, Michael Kerger, Ken Chow, Chayanica Nasa, Melanie Le Page, Natalie Lister, Simon Monard, Justin Peters, Phil Dundee, Scott G. Williams, Anthony J. Costello, Paul J. Neeson, Bhupinder Pal, Nicholas D. Huntington, Niall M. Corcoran, Anthony T. Papenfuss, Christopher M. Hovens

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Interferon-epsilon is a novel regulator of NK cell responses in the uterus 由 Jemma R Mayall, Jay C Horvat, Niamh E Mangan, Anne Chevalier, Huw McCarthy, Daniel Hampsey, Chantal Donovan, Alexandra C Brown, Antony Y Matthews, Nicole A de Weerd, Eveline D de Geus, Malcolm R Starkey, Richard Y Kim, Katie Daly, Bridie J Goggins, Simon Keely, Steven Maltby, Rennay Baldwin, Paul S Foster, Michael J Boyle, Pradeep S Tanwar, Nicholas D Huntington, Paul J Hertzog, Philip M Hansbro

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Context-restricted PD-(L)1 checkpoint agonism by CTLA4-Ig therapies inhibits T cell activity 由 Ethan P. Oxley, Nadia J. Kershaw, Cynthia Louis, Katharine J. Goodall, Maximilian M. Garwood, Skye Min Jee Ho, Veronica T.F. Voo, Hae-Young Park, Josephine Iaria, Lilian L.L. Wong, Ariel G. Lebenbaum, Stephanie Wiranata, Ee Shan Pang, Emily S.J. Edwards, Damian B. D’Silva, Jacinta Hansen, Menno C. van Zelm, Meredith O’Keeffe, P. Mark Hogarth, Nicole M. Haynes, Nicholas D. Huntington, Ian P. Wicks, Ross A. Dickins

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A point mutation in the Ncr1 signal peptide impairs the development of innate lymphoid cell subsets 由 Francisca F. Almeida, Sara Tognarelli, Antoine Marçais, Andrew J. Kueh, Miriam E. Friede, Yang Liao, Simon N. Willis, Kylie Luong, Fabrice Faure, Francois E. Mercier, Justine Galluso, Matthew Firth, Emilie Narni-Mancinelli, Bushra Rais, David T. Scadden, Francesco Spallotta, Sandra Weil, Ariane Giannattasio, Franziska Kalensee, Tobias Zöller, Nicholas D. Huntington, Ulrike Schleicher, Andreas G. Chiocchetti, Sophie Ugolini, Marco J. Herold, Wei Shi, Joachim Koch, Alexander Steinle, Eric Vivier, Thierry Walzer, Gabrielle T. Belz, Evelyn Ullrich

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