Mammalian Mitophagosome Formation: A Focus on the Early Signals and Steps ‌ Maria Zachari, Nicholas T. Ktistakis

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Editorial: Autophagy and Ageing: Ideas, Methods, Molecules ‌ Tassula Proikas-Cezanne, Nicholas T. Ktistakis

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Dynamics of mTORC1 activation in response to amino acids ‌ Maria Manifava, Matthew Smith, Sergio Rotondo, Simon Walker, Izabella Niewczas, Roberto Zoncu, Jonathan Clark, Nicholas T Ktistakis

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Autophagy initiation by ULK complex assembly on ER tubulovesicular regions marked by ATG9 vesicles ‌ Eleftherios Karanasios, Simon A. Walker, Hanneke Okkenhaug, Maria Manifava, Eric Hummel, Hans Zimmermann, Qashif Ahmed, Marie-Charlotte Domart, Lucy Collinson, Nicholas T. Ktistakis

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The immune system GTPase GIMAP6 interacts with the Atg8 homologue GABARAPL2 and is recruited to autophagosomes. ‌ John C Pascall, Sergio Rotondo, Aamir S Mukadam, David Oxley, Judith Webster, Simon A Walker, Jerry Piron, Christine Carter, Nicholas T Ktistakis, Geoffrey W Butcher

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Phospholipase D activity couples plasma membrane endocytosis with retromer dependent recycling ‌ Rajan Thakur, Aniruddha Panda, Elise Coessens, Nikita Raj, Shweta Yadav, Sruthi Balakrishnan, Qifeng Zhang, Plamen Georgiev, Bishal Basak, Renu Pasricha, Michael JO Wakelam, Nicholas T Ktistakis, Padinjat Raghu

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The brown adipocyte protein CIDEA promotes lipid droplet fusion via a phosphatidic acid-binding amphipathic helix ‌ David Barneda, Joan Planas-Iglesias, Maria L Gaspar, Dariush Mohammadyani, Sunil Prasannan, Dirk Dormann, Gil-Soo Han, Stephen A Jesch, George M Carman, Valerian Kagan, Malcolm G Parker, Nicholas T Ktistakis, Judith Klein-Seetharaman, Ann M Dixon, Susan A Henry, Mark Christian

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Temporal inhibition of autophagy reveals segmental reversal of ageing with increased cancer risk ‌ Liam D. Cassidy, Andrew R. J. Young, Christopher N. J. Young, Elizabeth J. Soilleux, Edward Fielder, Bettina M. Weigand, Anthony Lagnado, Rebecca Brais, Nicholas T. Ktistakis, Kimberley A. Wiggins, Katerina Pyrillou, Murray C. H. Clarke, Diana Jurk, Joao F. Passos, Masashi Narita

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