Editorial: Computational systems biomedicine by Richa Batra, Priyanka Baloni, Nicolas Alcaraz, Anne-Christin Hauschild, Alejandra Cervera

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Promoter sequence and architecture determine expression variability and confer robustness to genetic variants by Hjörleifur Einarsson, Marco Salvatore, Christian Vaagensø, Nicolas Alcaraz, Jette Bornholdt, Sarah Rennie, Robin Andersson

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On the performance of de novo pathway enrichment by Richa Batra, Nicolas Alcaraz, Kevin Gitzhofer, Josch Pauling, Henrik J. Ditzel, Marc Hellmuth, Jan Baumbach, Markus List

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Robust de novo pathway enrichment with KeyPathwayMiner 5 [version 1; referees: 2 approved] by Nicolas Alcaraz, Markus List, Martin Dissing-Hansen, Marc Rehmsmeier, Qihua Tan, Jan Mollenhauer, Henrik J. Ditzel, Jan Baumbach

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Comparative transcriptome analysis reveals key epigenetic targets in SARS-CoV-2 infection by Marisol Salgado-Albarrán, Erick I. Navarro-Delgado, Aylin Del Moral-Morales, Nicolas Alcaraz, Jan Baumbach, Rodrigo González-Barrios, Ernesto Soto-Reyes

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Association of <i>SLC12A1</i> and GLUR4 Ion Transporters with Neoadjuvant Chemoresistance in Luminal Locally Advanced Breast Cancer by Montserrat Justo-Garrido, Alejandro López-Saavedra, Nicolás Alcaraz, Carlo C. Cortés-González, Luis F. Oñate-Ocaña, Claudia Haydee Sarai Caro-Sánchez, Clementina Castro-Hernández, Cristian Arriaga-Canon, José Díaz-Chávez, Luis A. Herrera

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Orthologous proteins of experimental de- and remyelination are differentially regulated in the CSF proteome of multiple sclerosis subtypes. by Nellie A Martin, Arkadiusz Nawrocki, Viktor Molnar, Maria L Elkjaer, Eva K Thygesen, Miklos Palkovits, Peter Acs, Tobias Sejbaek, Helle H Nielsen, Zoltan Hegedus, Finn Sellebjerg, Tihamer Molnar, Eudes G V Barbosa, Nicolas Alcaraz, Ferenc Gallyas, Asa F Svenningsen, Jan Baumbach, Hans Lassmann, Martin R Larsen, Zsolt Illes

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Genomic Profile in a Non-Seminoma Testicular Germ-Cell Tumor Cohort Reveals a Potential Biomarker of Sensitivity to Platinum-Based Therapy by Rodrigo González-Barrios, Nicolás Alcaraz, Michel Montalvo-Casimiro, Alejandra Cervera, Cristian Arriaga-Canon, Paulina Munguia-Garza, Diego Hinojosa-Ugarte, Nora Sobrevilla-Moreno, Karla Torres-Arciga, Julia Mendoza-Perez, José Diaz-Chavez, Carlo Cesar Cortes-González, Clementina Castro-Hernández, Jorge Martínez-Cedillo, Ana Scavuzzo, Delia Pérez-Montiel, Miguel A. Jiménez-Ríos, Luis A. Herrera

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The Evolutionary Landscape of SARS-CoV-2 Variant B.1.1.519 and Its Clinical Impact in Mexico City by Alberto Cedro-Tanda, Laura Gómez-Romero, Nicolás Alcaraz, Guillermo de Anda-Jauregui, Fernando Peñaloza, Bernardo Moreno, Marco A. Escobar-Arrazola, Oscar A. Ramirez-Vega, Paulina Munguia-Garza, Francisco Garcia-Cardenas, Mireya Cisneros-Villanueva, Jose L. Moreno-Camacho, Jorge Rodriguez-Gallegos, Marco A. Luna-Ruiz Esparza, Miguel A. Fernández Rojas, Alfredo Mendoza-Vargas, Juan Pablo Reyes-Grajeda, Abraham Campos-Romero, Ofelia Angulo, Rosaura Ruiz, Claudia Sheinbaum-Pardo, José Sifuentes-Osornio, David Kershenobich, Alfredo Hidalgo-Miranda, Luis A. Herrera

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