Inflammation and anti-inflammatory approaches in myeloproliferative neoplasm by Steffen Koschmieder, Nicolas Chatain

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Progression of Myeloproliferative Neoplasms (MPN): Diagnostic and Therapeutic Perspectives by Julian Baumeister, Nicolas Chatain, Alexandros Marios Sofias, Twan Lammers, Steffen Koschmieder

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P988: MUTANT CALRETICULIN AND JAK2V617F DRIVER MUTATIONS INDUCE DISTINCT MITOTIC DEFECTS IN MYELOPROLIFERATIVE NEOPLASMS by Kristin Holl, Nicolas Chatain, Nathalie Brock, Susanne Krapp, Julian Baumeister, Steffen Koschmieder, Wolfram Antonin, Daniel Moreno-Andrés

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Calreticulin and JAK2V617F driver mutations induce distinct mitotic defects in myeloproliferative neoplasms by Kristin Holl, Nicolas Chatain, Susanne Krapp, Julian Baumeister, Tiago Maié, Sarah Schmitz, Anja Scheufen, Nathalie Brock, Steffen Koschmieder, Daniel Moreno-Andrés

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P1004: ACTIVATING MUTATIONS IN JAK2 AND CALR DIFFERENTIALLY AFFECT INTRACELLULAR CALCIUM LEVELS AND CALCIUM FLUX by Vikas Bhuria, Tobias Franz, Conny Baldauf, Martin Böttcher, Nicolas Chatain, Steffen Koschmieder, Tim H Brümmendorf, Dimitrios Mougiakakos, Burkhart Schraven, Sascha Kahlfuß, Thomas Fischer

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Activating mutations in JAK2 and CALR differentially affect intracellular calcium flux in store operated calcium entry by Vikas Bhuria, Tobias Franz, Conny Baldauf, Martin Böttcher, Nicolas Chatain, Steffen Koschmieder, Tim H. Brümmendorf, Dimitrios Mougiakakos, Burkhart Schraven, Sascha Kahlfuß, Thomas Fischer

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Targeting cytokine-induced leukemic stem cell persistence in chronic myeloid leukemia by IKK2-inhibition by Marlena Bütow, Fabio J. Testaquadra, Julian Baumeister, Tiago Maié, Nicolas Chatain, Timo Jaquet, Stefan Tillmann, Martina Crysandt, Ivan G. Costa, Tim H. Brümmendorf, Mirle Schemionek

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Myelofibrosis at diagnosis is associated with the failure of treatment-free remission in CML patients by Henrike Jacobi, Henrike Jacobi, Margherita Vieri, Margherita Vieri, Marlena Bütow, Marlena Bütow, Carolina Y. Namasu, Laura Flüter, Ivan G. Costa, Tiago Maié, Katharina Lindemann-Docter, Nicolas Chatain, Nicolas Chatain, Fabian Beier, Fabian Beier, Michael Huber, Wolfgang Wagner, Wolfgang Wagner, Wolfgang Wagner, Martina Crysandt, Martina Crysandt, Tim H. Brümmendorf, Tim H. Brümmendorf, Mirle Schemionek, Mirle Schemionek

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The telomerase inhibitor imetelstat differentially targets JAK2V617F versus CALR mutant myeloproliferative neoplasm cells and inhibits JAK-STAT signaling by Kathrin Olschok, Kathrin Olschok, Bianca Altenburg, Bianca Altenburg, Marcelo A. S. de Toledo, Marcelo A. S. de Toledo, Angela Maurer, Angela Maurer, Anne Abels, Anne Abels, Fabian Beier, Fabian Beier, Deniz Gezer, Deniz Gezer, Susanne Isfort, Susanne Isfort, Katrin Paeschke, Katrin Paeschke, Tim H. Brümmendorf, Tim H. Brümmendorf, Martin Zenke, Martin Zenke, Nicolas Chatain, Nicolas Chatain, Steffen Koschmieder, Steffen Koschmieder

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Evaluation of Chiral Organosulfur Compounds on Their Activity against the Malaria Parasite <em>Plasmodium falciparum</em> by Che Julius Ngwa, Rabea Stratmann, Jean Pierre Musabyimana, Kristina Pannen, Jan-Hendrik Schöbel, Marcus Frings, Ingo Schiffers, Calogero Quaranta, Steffen Koschmieder, Nicolas Chatain, Gabriele Pradel, Carsten Bolm

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P1008: THE TELOMERASE INHIBITOR IMETELSTAT DIFFERENTIALLY TARGETS JAK2V617F- VERSUS CALR-MUTANT MYELOPROLIFERATIVE NEOPLASM CELLS AND INHIBITS JAK-STAT SIGNALING by Kathrin Olschok, Bianca Altenburg, Marcelo A.S. de Toledo, Angela Maurer, Anne Abels, Fabian Beier, Deniz Gezer, Susanne Isfort, Tim H Brümmendorf, Martin Zenke, Nicolas Chatain, Steffen Koschmieder

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P653: CML LONG-TERM LEUKEMIC STEM CELL PERSISTENCE IS INFLUENCED BY MYELOFIBROSIS AT DIAGNOSIS by Henrike Jacobi, Margherita Vieri, Carolina Y. Namasu, Laura Flüter, Ivan G. Costa, Tiago Maié, Nicolas Chatain, Fabian Beier, Michael Huber, Martina Crysandt, Tim H. Brümmendorf, Mirle Schemionek-Reinders

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Non-canonical Hedgehog signaling mediates profibrotic hematopoiesis-stroma crosstalk in myeloproliferative neoplasms by Jessica E. Pritchard, Juliette E. Pearce, Inge A.M. Snoeren, Stijn N.R. Fuchs, Katrin Götz, Fabian Peisker, Silke Wagner, Adam Benabid, Niklas Lutterbach, Vanessa Klöker, James S. Nagai, Monica T. Hannani, Anna K. Galyga, Ellen Sistemich, Bella Banjanin, Niclas Flosdorf, Eric Bindels, Kathrin Olschok, Katharina Biaesch, Nicolas Chatain, Neha Bhagwat, Andrew Dunbar, Rita Sarkis, Olaia Naveiras, Marie-Luise Berres, Steffen Koschmieder, Ross L. Levine, Ivan G. Costa, Hélène F.E. Gleitz, Rafael Kramann, Rebekka K. Schneider

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