ICM experimental is growing, from bench via bedside to big data—and back! by Nicole P. Juffermans

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Response to “Co-infections in COVID-19 critically ill and antibiotic management: a prospective cohort analysis” by Marieke B. Nieuwenhuis, Stefaan Van Biesen, Nicole P. Juffermans

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The impact of biological age of red blood cell on in vitro endothelial activation markers by Abdulrahman Alshalani, Abdulrahman Alshalani, Boukje M. Beuger, Anita M. Tuip-de Boer, Robin van Bruggen, Jason P. Acker, Jason P. Acker, Nicole P. Juffermans, Nicole P. Juffermans

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The importance of discovery science in the development of therapies for the critically ill by Nicole P. Juffermans, Peter Radermacher, John G. Laffey, on behalf of the Translational Biology Group

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COVID-19: What we’ve done well and what we could or should have done better—the 4 Ps by Jean-Louis Vincent, Julia Wendon, Greg S. Martin, Nicole P. Juffermans, Jacques Creteur, Maurizio Cecconi

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Why translational research matters: proceedings of the third international symposium on acute lung injury translational research (INSPIRES III) by Nicole P. Juffermans, Marcus Schultz, Lieuwe D. Bos, Oscar Penuelas, John Laffey, Jose A. Lorente

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Hyperoxemia and hypoxemia impair cellular oxygenation: a study in healthy volunteers by Bashar N. Hilderink, Reinier F. Crane, Bas van den Bogaard, Janesh Pillay, Nicole P. Juffermans

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Severity of illness influences the microcirculatory response to red blood cell transfusion in the critically ill: an observational cohort study by Lisa van Manen, Jessica M. Deurvorst, Maike E. van Hezel, Margit Boshuizen, Robin van Bruggen, Nicole P. Juffermans

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Therapeutic application of recombinant human ADAMTS-13 improves shock reversal and coagulation status in a trauma hemorrhage and transfusion rat model by Mathijs R. Wirtz, Daan P. van den Brink, Joris J. T. H. Roelofs, J. Carel Goslings, Nicole P. Juffermans

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Rotational thromboelastometry in critically ill COVID‐19 patients does not predict thrombosis by Romein W. G. Dujardin, Gabriel Garcia Rosenbaum, Timo C. J. Klercq, Jecko Thachil, Nathan D. Nielsen, Nicole P. Juffermans

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Heliox allows for lower minute volume ventilation in an animal model of ventilator-induced lung injury. by Charlotte J Beurskens, Hamid Aslami, Friso M de Beer, Margreeth B Vroom, Benedikt Preckel, Janneke Horn, Nicole P Juffermans

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Hypothermia as a predictor for mortality in trauma patients at admittance to the intensive care unit by Kirsten Balvers, Marjolein Van der Horst, Maarten Graumans, Christa Boer, Jan M Binnekade, J Carel Goslings, Nicole P Juffermans

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Risk factors for trauma-induced coagulopathy- and transfusion-associated multiple organ failure in severely injured trauma patients by Kirsten eBalvers, Kirsten eBalvers, Mathijs R Wirtz, Mathijs R Wirtz, Susan evan Dieren, J Carel eGoslings, Nicole P Juffermans

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A randomized trial of remote ischemic preconditioning and control treatment for cardioprotection in sevoflurane-anesthetized CABG patients by Rianne Nederlof, Nina C. Weber, Nicole P. Juffermans, Bas A. M. J. de Mol, Markus W. Hollmann, Benedikt Preckel, Coert J. Zuurbier

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Fluid restriction reduces pulmonary edema in a model of acute lung injury in mechanically ventilated rats. by Sarah A Ingelse, Jenny Juschten, Martinus A W Maas, Gustavo Matute-Bello, Nicole P Juffermans, Job B M van Woensel, Reinout A Bem

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Transfusion of female blood in a rat model is associated with red blood cells entrapment in organs by Abdulrahman Alshalani, Marit B. de Wissel, Anita M. Tuip-de Boer, Joris J. T. H. Roelofs, Robin van Bruggen, Jason P. Acker, Nicole P. Juffermans

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Transfusion of female blood in a rat model is associated with red blood cells entrapment in organs. by Abdulrahman Alshalani, Marit B de Wissel, Anita M Tuip-de Boer, Joris J T H Roelofs, Robin van Bruggen, Jason P Acker, Nicole P Juffermans

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Severe Murine Typhus with Pulmonary System Involvement by Thomas W. van der Vaart, Pieter P.A.M. van Thiel, Nicole P. Juffermans, Michèle van Vugt, Suzanne E. Geerlings, Martin P. Grobusch, Abraham Goorhuis

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Association between viscoelastic tests-guided therapy with synthetic factor concentrates and allogenic blood transfusion in liver transplantation: a before-after study by Raffael P. C. Zamper, Thiago C. Amorim, Veronica N. F. Queiroz, Jordana D. O. Lira, Luiz Guilherme V. Costa, Flavio Takaoka, Nicole P. Juffermans, Ary S. Neto

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The Effects of Heparan Sulfate Infusion on Endothelial and Organ Injury in a Rat Pneumosepsis Model by Daan P. van den Brink, Derek J. B. Kleinveld, Annabel Bongers, Jaël Vos, Joris T. H. Roelofs, Nina C. Weber, Jaap D. van Buul, Nicole P. Juffermans

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