A phase 2 double-blind placebo-controlled 24-week treatment clinical study of the p38 alpha kinase inhibitor neflamapimod in mild Alzheimer’s disease by Niels D. Prins, John E. Harrison, Hui-May Chu, Kelly Blackburn, John J. Alam, Philip Scheltens, for the REVERSE-SD Study Investigators

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Microbleeds are associated with depressive symptoms in Alzheimer's disease by Anna E. Leeuwis, Niels D. Prins, Astrid M. Hooghiemstra, Marije R. Benedictus, Philip Scheltens, Frederik Barkhof, Wiesje M. van derFlier

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Experiences of and recommendations on clinical trial design in Alzheimer’s disease from the participant’s point of view: a mixed-methods study in two clinical trial centers in the... by Lois Ottenhoff, Everard G. B. Vijverberg, Leonie N. C. Visser, Merike Verijp, Niels D. Prins, Wiesje M. Van der Flier, Sietske A. M. Sikkes

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Pooling Alzheimer's disease clinical trial data to develop personalized medicine approaches is easier said than done: A proof‐of‐principle study and call to action by Mark A. Dubbelman, Eleonora M. Vromen, Betty M. Tijms, Johannes Berkhof, Lois Ottenhoff, Everard G. B. Vijverberg, Niels D. Prins, Wiesje M. van derFlier, Sietske A. M. Sikkes

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Safety, tolerability and efficacy of the glutaminyl cyclase inhibitor PQ912 in Alzheimer’s disease: results of a randomized, double-blind, placebo-controlled phase 2a study by Philip Scheltens, Merja Hallikainen, Timo Grimmer, Thomas Duning, Alida A Gouw, Charlotte E Teunissen, Alle Meije Wink, Paul Maruff, John Harrison, Caroline M van Baal, Suzanne Bruins, Inge Lues, Niels D Prins

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Vascular Cognitive Impairment and cognitive decline; a longitudinal study comparing different types of vascular brain injury - The TRACE-VCI study by Jooske MF Boomsma, Lieza G Exalto, Frederik Barkhof, Anna E Leeuwis, Niels D Prins, Philip Scheltens, Charlotte E Teunissen, Henry C Weinstein, Geert Jan Biessels, Wiesje M van der Flier, On-behalf-of-the-TRACE-VCI-study-group

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Decreased integrity of the monoaminergic tract is associated with a positive response to MPH in patients with vascular cognitive impairment - proof of principle study STREAM-VCI by Jolene F Leijenaar, Silvia Ingala, Carole H Sudre, Henk-Jan MM Mutsaerts, Anna E. Leeuwis, Wiesje M van der Flier, Philip Scheltens, Henry C Weinstein, Frederik Barkhof, Joop van Gerven, Geert Jan Groeneveld, Niels D Prins

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Sex differences in memory clinic patients with possible vascular cognitive impairment by Lieza G. Exalto, Jooske M. F. Boomsma, Rosha Babapour Mofrad, Frederik Barkhof, Onno N. Groeneveld, Rutger Heinen, Hugo J. Kuijf, Anna E. Leeuwis, Niels D. Prins, Geert Jan Biessels, Wiesje M. vd Flier, TRACE‐VCI study group

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Dutch Brain Research Registry for study participant recruitment: Design and first results by Marissa D. Zwan, Wiesje M. van derFlier, Solange Cleutjens, Tamara C Schouten, Lisa Vermunt, Roos J. Jutten, Ingrid S. vanMaurik, Sietske A.M. Sikkes, Derek Flenniken, Taylor Howell, Michael W. Weiner, Philip Scheltens, Niels D. Prins

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Risk of dementia in APOE ε4 carriers is mitigated by a polygenic risk score by Jarith L. Ebenau, Sven J. van derLee, Marc Hulsman, Niccolò Tesi, Iris E. Jansen, Inge M.W. Verberk, Mardou vanLeeuwenstijn, Charlotte E. Teunissen, Frederik Barkhof, Niels D. Prins, Philip Scheltens, Henne Holstege, Bart N.M. vanBerckel, Wiesje M. van derFlier

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Cerebral Blood Flow and Cognitive Functioning in a Community-Based, Multi-Ethnic Cohort: The SABRE Study by Anna E. Leeuwis, Lorna A. Smith, Andrew Melbourne, Alun D. Hughes, Alun D. Hughes, Marcus Richards, Niels D. Prins, Magdalena Sokolska, David Atkinson, Therese Tillin, Hans R. Jäger, Nish Chaturvedi, Nish Chaturvedi, Wiesje M. van der Flier, Wiesje M. van der Flier, Frederik Barkhof, Frederik Barkhof

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Subjective Cognitive Impairment Cohort (SCIENCe): study design and first results by Rosalinde E. R. Slot, Sander C. J. Verfaillie, Jozefien M. Overbeek, Tessa Timmers, Linda M. P. Wesselman, Charlotte E. Teunissen, Annemiek Dols, Femke H. Bouwman, Niels D. Prins, Frederik Barkhof, Adriaan A. Lammertsma, Bart N. M. Van Berckel, Philip Scheltens, Sietske A. M. Sikkes, Wiesje M. Van der Flier

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Changes in Brain-Health Related Modifiable Risk Factors in Older Adults After One Year of COVID-19-Restrictions by Lisa Waterink, Els D. Bakker, Leonie N. C. Visser, Leonie N. C. Visser, Francesca Mangialasche, Miia Kivipelto, Miia Kivipelto, Miia Kivipelto, Miia Kivipelto, Kay Deckers, Sebastian Köhler, Sietske A. M. Sikkes, Sietske A. M. Sikkes, Niels D. Prins, Philip Scheltens, Philip Scheltens, Wiesje M. van der Flier, Wiesje M. van der Flier, Marissa D. Zwan

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Amyloid-β Load Is Related to Worries, but Not to Severity of Cognitive Complaints in Individuals With Subjective Cognitive Decline: The SCIENCe Project by Sander C. J. Verfaillie, Sander C. J. Verfaillie, Sander C. J. Verfaillie, Tessa Timmers, Tessa Timmers, Tessa Timmers, Rosalinde E. R. Slot, Rosalinde E. R. Slot, Chris W. J. van der Weijden, Chris W. J. van der Weijden, Linda M. P. Wesselman, Linda M. P. Wesselman, Niels D. Prins, Niels D. Prins, Sietske A. M. Sikkes, Sietske A. M. Sikkes, Sietske A. M. Sikkes, Maqsood Yaqub, Maqsood Yaqub, Annemiek Dols, Annemiek Dols, Annemiek Dols, Adriaan A. Lammertsma, Adriaan A. Lammertsma, Philip Scheltens, Philip Scheltens, Rik Ossenkoppele, Rik Ossenkoppele, Rik Ossenkoppele, Bart N. M. van Berckel, Bart N. M. van Berckel, Wiesje M. van der Flier, Wiesje M. van der Flier, Wiesje M. van der Flier

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Prescreening for European Prevention of Alzheimer Dementia (EPAD) trial-ready cohort: impact of AD risk factors and recruitment settings by Lisa Vermunt, Graciela Muniz-Terrera, Lea ter Meulen, Colin Veal, Kaj Blennow, Archie Campbell, Isabelle Carrié, Julien Delrieu, Karine Fauria, Gema Huesa Rodríguez, Silvia Ingala, Natalie Jenkins, José Luis Molinuevo, Pierre-Jean Ousset, David Porteous, Niels D. Prins, Alina Solomon, Brian D. Tom, Henrik Zetterberg, Marissa Zwan, Craig W. Ritchie, Philip Scheltens, Gerald Luscan, Anthony J. Brookes, Pieter Jelle Visser, for the IMI-EPAD collaborators

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Cerebral blood flow and cognitive functioning in patients with disorders along the heart–brain axis by Anna E. Leeuwis, Astrid M. Hooghiemstra, Esther E. Bron, Sanne Kuipers, Eline A. Oudeman, Tugba Kalay, Hans‐Peter Brunner‐La Rocca, L. Jaap Kappelle, Robert J. vanOostenbrugge, Jacoba P. Greving, Wiro J. Niessen, Mark A. vanBuchem, Matthias J.P. vanOsch, Albert C. vanRossum, Niels D. Prins, Geert‐Jan Biessels, Frederik Barkhof, Heart–Brain Connection consortium, Wiesje M. vander Flier

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Preclinical and randomized clinical evaluation of the p38α kinase inhibitor neflamapimod for basal forebrain cholinergic degeneration by Ying Jiang, John J. Alam, Stephen N. Gomperts, Paul Maruff, Afina W. Lemstra, Ursula A. Germann, Philip H. Stavrides, Sandipkumar Darji, Sandeep Malampati, James Peddy, Cynthia Bleiwas, Monika Pawlik, Anna Pensalfini, Dun-Sheng Yang, Shivakumar Subbanna, Balapal S. Basavarajappa, John F. Smiley, Amanda Gardner, Kelly Blackburn, Hui-May Chu, Niels D. Prins, Charlotte E. Teunissen, John E. Harrison, Philip Scheltens, Ralph A. Nixon

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