Bispecific Chimeric Antigen Receptor T Cell Therapy for B Cell Malignancies and Multiple Myeloma by Robert J. Cronk, Joanna Zurko, Nirav N. Shah

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Gut microbiome and CAR-T therapy by Muhammad Bilal Abid, Nirav N. Shah, Theresa C. Maatman, Parameswaran N. Hari

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Bone Marrow Aplasia after CAR-T-Cell Therapy for Relapsed/Refractory Burkitt’s Lymphoma by Troy J. Kenkel, Nithya Sridhar, Lindsay R. Hammons, Maria Hintzke, Nirav N. Shah

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P1082: RESULTS FROM A PHASE 1/2 STUDY OF TANDEM, BISPECIFIC ANTI-CD20/ANTI-CD19 (LV20.19) CAR T-CELLS FOR MANTLE CELL LYMPHOMA by Nirav N Shah, Timothy Fenske, Bryon Johnson, Aniko Szabo, Sumana Devata, Walter Longo, Tyce Kearl, Anthony Zamora, Parameswaran Hari, Dina Schneider, Mehdi Hamadani

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P618: LONG-TERM SAFETY WITH ≥12 MONTHS OF PIRTOBRUTINIB IN RELAPSED/REFRACTORY (R/R) B-CELL MALIGNANCIES by Wojciech Jurczak, Catherine C. Coombs, Nirav N. Shah, Jennifer Woyach, Chan Y. Cheah, Krish Patel, Kami Maddocks, Yucai Wang, Catherine E. Muehlenbein, Chunxiao Wang, Sarang Abhyankar, Donald E. Tsai, Toby A. Eyre

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Patient-reported outcomes and neurotoxicity markers in patients treated with bispecific LV20.19 CAR T cell therapy by Jennifer M. Knight, Aniko Szabo, Igli Arapi, Ruizhe Wu, Amanda Emmrich, Edward Hackett, Garrett Sauber, Sharon Yim, Bryon Johnson, Parameswaran Hari, Dina Schneider, Boro Dropulic, Rachel N. Cusatis, Steve W. Cole, Cecilia J. Hillard, Nirav N. Shah

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S224: HIGH COMPLETE RESPONSE RATE WITH TNB-486, A NOVEL CD19XCD3 T-CELL ENGAGER, IN RELAPSED/REFRACTORY FOLLICULAR LYMPHOMA: INTERIM RESULTS FROM AN ONGOING PHASE 1 STUDY by Ryan Jacobs, Ranjit Nair, Seok-Goo Cho, Sumana Devata, Sameh Gaballa, Dok Hyun Yoon, Don Stevens, Jin Seok Kim, Nirav N Shah, Denise Marie Brennan, Jason Law, Robin Lesley, Rob Chen, Alessandra Forcina, Ben Buelow, Jing-Zhou Hou

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P636: A FIRST-IN-HUMAN PHASE 1 STUDY OF ORAL LOXO-338, A SELECTIVE BCL2 INHIBITOR, IN PATIENTS WITH ADVANCED HEMATOLOGIC MALIGNANCIES by Michal Kwiatek, Guru Subramanian Guru Murthy, Marc Hoffmann, Lindsey Roeker, Benoit Tessoulin, Alexey Danilov, Alvaro J. Alencar, Nirav N. Shah, Herve Ghesquieres, Steven Le Gouill, Wojciech Jurczak, Anthony R. Mato, Vishalkumar Patel, Yingying Guo-Avrutin, James M. Pauff, Maciej Kazmierczak

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P1087: PIRTOBRUTINIB IN COVALENT BTK-INHIBITOR PRE-TREATED MANTLE CELL LYMPHOMA: UPDATED RESULTS AND SUBGROUP ANALYSIS FROM THE PHASE 1/2 BRUIN STUDY WITH >3 YEARS FOLLOW-UP FROM S... by Wojciech Jurczak, Pier Luigi Zinzani, Toby A. Eyre, Chan Y. Cheah, Chaitra S. Ujjani, Koji Izutsu, Shuo MA, Ian Flinn, Alvaro J. Alencar, David Lewis, Krish Patel, Kami Maddocks, Yucai Wang, Talha Munir, Andrew D. Zelenetz, Minna Balbas, Donald E. Tsai, Chunxiao Wang, Michael L. Wang, Nirav N. Shah

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S146: GENOMIC EVOLUTION AND RESISTANCE TO PIRTOBRUTINIB IN COVALENT BTK-INHIBITOR (CBTKI) PRE-TREATED CHRONIC LYMPHOCYTIC LEUKEMIA (CLL) PATIENTS: RESULTS FROM THE PHASE I/II BRUIN... by Jennifer R. Brown, Sai Prasad Desikan, Bastien Nguyen, Helen Won, Shady Tantawy, Samuel Clark Mcneely, Narasimha Marella, Kevin Ebata, Jennifer Woyach, Krish Patel, Constantine Tam, Toby Eyre, Chan Cheah, Nirav N Shah, Paolo Ghia, Wojciech Jurczak, Minna Balbas, Binoj Nair, Paolo Abada, Chunxiao Wang, Denise Wang, Anthony R. Mato, Varsha Gandhi, William G. Wierda

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Rare Germline Variants in Chordoma-Related Genes and Chordoma Susceptibility by Sally Yepes, Nirav N. Shah, Jiwei Bai, Hela Koka, Chuzhong Li, Songbai Gui, Mary Lou McMaster, Yanzi Xiao, Kristine Jones, Mingyi Wang, Aurelie Vogt, Bin Zhu, Bin Zhu, Amy Hutchinson, Meredith Yeager, Belynda Hicks, Brian Carter, Neal D. Freedman, Laura Beane-Freeman, Stephen J. Chanock, Yazhuo Zhang, Dilys M. Parry, Xiaohong R. Yang, Alisa M. Goldstein

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Outcomes of patients with secondary central nervous system lymphoma following CAR T-cell therapy: a multicenter cohort study by Narendranath Epperla, Lei Feng, Nirav N. Shah, Lindsey Fitzgerald, Harsh Shah, Deborah M. Stephens, Catherine J. Lee, Thomas Ollila, Geoffrey Shouse, Alexey V. Danilov, Kevin A. David, Pallawi Torka, Hamza Hashmi, Brian Hess, Stefan K. Barta, Jason T. Romancik, Jonathon B. Cohen, Kaitlin Annunzio, Adam S. Kittai, John Reneau, Joanna Zurko, Imran A. Nizamuddin, Jane N. Winter, Leo I. Gordon, Shuo Ma, Romil Patel, Loretta Nastoupil, Sairah Ahmed, Reem Karmali

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Efficacy of bendamustine and rituximab in unfit patients with previously untreated chronic lymphocytic leukemia. Indirect comparison with ibrutinib in a real‐world setting. A GIMEM... by Antonio Cuneo, Anthony R. Mato, Gian Matteo Rigolin, Alfonso Piciocchi, Massimo Gentile, Luca Laurenti, John N. Allan, John M. Pagel, Danielle M. Brander, Brian T. Hill, Allison Winter, Nicole Lamanna, Constantine S. Tam, Ryan Jacobs, Frederick Lansigan, Paul M. Barr, Mazyar Shadman, Alan P. Skarbnik, Jeffrey J. Pu, Alison R. Sehgal, Stephen J. Schuster, Nirav N. Shah, Chaitra S. Ujjani, Lindsey Roeker, Ester Maria Orlandi, Atto Billio, Livio Trentin, Martin Spacek, Monia Marchetti, Alessandra Tedeschi, Fiorella Ilariucci, Gianluca Gaidano, Michael Doubek, Lucia Farina, Stefano Molica, Francesco Di Raimondo, Marta Coscia, Francesca Romana Mauro, Javier de la Serna, Angeles Medina Perez, Isacco Ferrarini, Giuseppe Cimino, Maurizio Cavallari, Rosalba Cucci, Marco Vignetti, Robin Foà, Paolo Ghia, the GIMEMA, European Research Initiative (ERIC) on CLL, US study group

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