A patient safety knowledge graph supporting vaccine product development by Andrew M. Simms, Anshul Kanakia, Muhammad Sipra, Bhaskar Dutta, Noel Southall

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An integrative knowledge graph for rare diseases, derived from the Genetic and Rare Diseases Information Center (GARD) by Qian Zhu, Dac-Trung Nguyen, Ivan Grishagin, Noel Southall, Eric Sid, Anne Pariser

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COPI complex is a regulator of lipid homeostasis. by Mathias Beller, Carole Sztalryd, Noel Southall, Ming Bell, Herbert Jäckle, Douglas S Auld, Brian Oliver

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High throughput screening for small molecule therapy for Gaucher disease using patient tissue as the source of mutant glucocerebrosidase. by Ehud Goldin, Wei Zheng, Omid Motabar, Noel Southall, Jae Hyuk Choi, Juan Marugan, Christopher P Austin, Ellen Sidransky

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Novel patient cell-based HTS assay for identification of small molecules for a lysosomal storage disease. by Haifeng Geng, Grace Whiteley, Jameson Ribbens, Wei Zheng, Noel Southall, Xin Hu, Juan J Marugan, Marc Ferrer, Gustavo H B Maegawa

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Rapid antimicrobial susceptibility test for identification of new therapeutics and drug combinations against multidrug-resistant bacteria by Wei Sun, Rebecca A Weingarten, Miao Xu, Noel Southall, Sheng Dai, Paul Shinn, Philip E Sanderson, Peter R Williamson, Karen M Frank, Wei Zheng

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Inhibition of ceramide metabolism sensitizes human leukemia cells to inhibition of BCL2-like proteins. by Lavona Casson, Lauren Howell, Lesley A Mathews, Marc Ferrer, Noel Southall, Rajarshi Guha, Jonathan M Keller, Craig Thomas, Leah J Siskind, Levi J Beverly

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Correction: Rapid Identification of Antifungal Compounds against Using High Throughput Drug Repurposing Screens. by Wei Sun, Yoon-Dong Park, Janyce A. Sugui, Annette Fothergill, Noel Southall, Paul Shinn, John C. McKew, Kyung J. Kwon-Chung, Wei Zheng, Peter R. Williamson

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Correction: Rapid Identification of Antifungal Compounds against Using High Throughput Drug Repurposing Screens. by Wei Sun, Yoon-Dong Park, Janyce A. Sugui, Annette Fothergill, Noel Southall, Paul Shinn, John C. McKew, Kyung J. Kwon-Chung, Wei Zheng, Peter R. Williamson

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Identification of Small Molecule Inhibitors of a Mir155 Transcriptional Reporter in Th17 Cells by Anju Singh, Myagmarjav Dashynam, Bryan Chim, Thelma M. Escobar, Xiuhuai Liu, Xin Hu, Samarjit Patnaik, Xin Xu, Noel Southall, Juan Marugan, Ajit Jadhav, Vanja Lazarevic, Stefan A. Muljo, Marc Ferrer

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Discovery of small molecule inhibitors that effectively disrupt IQGAP1-Cdc42 interaction in breast cancer cells by Samar Sayedyahossein, Jessica Smith, Elena Barnaeva, Zhigang Li, Jun Choe, Michael Ronzetti, Christopher Dextras, Xin Hu, Juan Marugan, Noel Southall, Bolormaa Baljinnyam, Louise Thines, Andy D. Tran, Marc Ferrer, David B. Sacks

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A high throughput screening assay system for the identification of small molecule inhibitors of gsp. by Nisan Bhattacharyya, Xin Hu, Catherine Z Chen, Lesley A Mathews Griner, Wei Zheng, James Inglese, Christopher P Austin, Juan J Marugan, Noel Southall, Susanne Neumann, John K Northup, Marc Ferrer, Michael T Collins

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Agonist-specific voltage-dependent gating of lysosomal two-pore Na+ channels by Xiaoli Zhang, Wei Chen, Ping Li, Raul Calvo, Noel Southall, Xin Hu, Melanie Bryant-Genevier, Xinghua Feng, Qi Geng, Chenlang Gao, Meimei Yang, Kaiyuan Tang, Marc Ferrer, Juan Jose Marugan, Haoxing Xu

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A high-throughput screening to identify small molecules that suppress huntingtin promoter activity or activate huntingtin-antisense promoter activity by Houda G. Khaled, Hongxuan Feng, Xin Hu, Xin Sun, Wang Zheng, Pan P. Li, Dobrila D. Rudnicki, Wenjuan Ye, Yu-Chi Chen, Noel Southall, Juan Marugan, Christopher A. Ross, Marc Ferrer, Mark J. Henderson, Russell L. Margolis

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Activation of mitochondrial TRAP1 stimulates mitochondria-lysosome crosstalk and correction of lysosomal dysfunction by Fannie W. Chen, Joanna P. Davies, Raul Calvo, Jagruti Chaudhari, Georgia Dolios, Mercedes K. Taylor, Samarjit Patnaik, Jean Dehdashti, Rebecca Mull, Patricia Dranchack, Amy Wang, Xin Xu, Emma Hughes, Noel Southall, Marc Ferrer, Rong Wang, Juan J. Marugan, Yiannis A. Ioannou

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c-Abl Activation Linked to Autophagy-Lysosomal Dysfunction Contributes to Neurological Impairment in Niemann-Pick Type A Disease by Tamara Marín, Andrés E. Dulcey, Fabián Campos, Catalina de la Fuente, Mariana Acuña, Mariana Acuña, Juan Castro, Claudio Pinto, María José Yañez, Cristian Cortez, David W. McGrath, Pablo J. Sáez, Kirill Gorshkov, Wei Zheng, Noel Southall, Maria Carmo-Fonseca, Juan Marugán, Alejandra R. Alvarez, Silvana Zanlungo

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Inhibition of PIP4Kγ ameliorates the pathological effects of mutant huntingtin protein by Ismael Al-Ramahi, Sai Srinivas Panapakkam Giridharan, Yu-Chi Chen, Samarjit Patnaik, Nathaniel Safren, Junya Hasegawa, Maria de Haro, Amanda K Wagner Gee, Steven A Titus, Hyunkyung Jeong, Jonathan Clarke, Dimitri Krainc, Wei Zheng, Robin F Irvine, Sami Barmada, Marc Ferrer, Noel Southall, Lois S Weisman, Juan Botas, Juan Jose Marugan

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Novel Phenotypic Outcomes Identified for a Public Collection of Approved Drugs from a Publicly Accessible Panel of Assays. by Jonathan A Lee, Paul Shinn, Susan Jaken, Sarah Oliver, Francis S Willard, Steven Heidler, Robert B Peery, Jennifer Oler, Shaoyou Chu, Noel Southall, Thomas S Dexheimer, Jeffrey Smallwood, Ruili Huang, Rajarshi Guha, Ajit Jadhav, Karen Cox, Christopher P Austin, Anton Simeonov, G Sitta Sittampalam, Saba Husain, Natalie Franklin, David J Wild, Jeremy J Yang, Jeffrey J Sutherland, Craig J Thomas

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Progress toward a universal biomedical data translator by Karamarie Fecho, Anne E. Thessen, Sergio E. Baranzini, Chris Bizon, Jennifer J. Hadlock, Sui Huang, Ryan T. Roper, Noel Southall, Casey Ta, Paul B. Watkins, Mark D. Williams, Hao Xu, William Byrd, Vlado Dančík, Marc P. Duby, Michel Dumontier, Gustavo Glusman, Nomi L. Harris, Eugene W. Hinderer, Greg Hyde, Adam Johs, Andrew I. Su, Guangrong Qin, Qian Zhu, The Biomedical Data Translator Consortium

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