Correction: IL-34 Induces the Differentiation of Human Monocytes into Immunosuppressive Macrophages. Antagonistic Effects of GM-CSF and IFNγ. by Etienne D. Foucher, Simon Blanchard, Laurence Preisser, Erwan Garo, Norbert Ifrah, Philippe Guardiola, Yves Delneste, Pascale Jeannin

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L-asparaginase for adult CD20 positive B-cell precursor acute lymphoblastic leukemia by Sébastien Maury, Françoise Huguet, Norbert Ifrah, Hervé Dombret, Marie-Christine Béné, for the Group for Research on Adult Acute Lymphoblastic Leukemia (GRAALL)

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Adding lomustine to idarubicin and cytarabine for induction chemotherapy in older patients with acute myeloid leukemia: the BGMT 95 trial results by Arnaud Pigneux, Virginie Perreau, Eric Jourdan, Norbert Vey, Nicole Dastugue, Françoise Huguet, Jean-Jacques Sotto, L. Rachid Salmi, Norbert Ifrah, Josy Reiffers

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Prospective long-term minimal residual disease monitoring using RQ-PCR in RUNX1-RUNX1T1-positive acute myeloid leukemia: results of the French CBF-2006 trial by Christophe Willekens, Odile Blanchet, Aline Renneville, Pascale Cornillet-Lefebvre, Cécile Pautas, Romain Guieze, Norbert Ifrah, Hervé Dombret, Eric Jourdan, Claude Preudhomme, Nicolas Boissel

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Autocrine IGF-1/IGF-1R signaling is responsible for constitutive PI3K/Akt activation in acute myeloid leukemia: therapeutic value of neutralizing anti-IGF-1R antibody by Nicolas Chapuis, Jérôme Tamburini, Pascale Cornillet-Lefebvre, Lucile Gillot, Valérie Bardet, Lise Willems, Sophie Park, Alexa S Green, Norbert Ifrah, François Dreyfus, Patrick Mayeux, Catherine Lacombe, Didier Bouscary

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Daunorubicin and Its Active Metabolite Pharmacokinetic Profiles in Acute Myeloid Leukaemia Patients: A Pharmacokinetic Ancillary Study of the BIG-1 Trial by Guillaume Drevin, Marie Briet, Caroline Bazzoli, Emmanuel Gyan, Aline Schmidt, Hervé Dombret, Corentin Orvain, Aurelien Giltat, Christian Recher, Norbert Ifrah, Philippe Guardiola, Mathilde Hunault-Berger, Chadi Abbara

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Changes in antithrombin and fibrinogen levels during induction chemotherapy with L-asparaginase in adult patients with acute lymphoblastic leukemia or lymphoblastic lymphoma. Use o... by Mathilde Hunault-Berger, Patrice Chevallier, Martine Delain, Claude-Eric Bulabois, Serge Bologna, Marc Bernard, Ingrid Lafon, Jérome Cornillon, Abdallah Maakaroun, Alexandra Tizon, Bruno Padrazzi, Norbert Ifrah, Yves Gruel

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Outcome of adult T-lymphoblastic lymphoma after acute lymphoblastic leukemia-type treatment: a GOELAMS trial by Mathilde Hunault, Malgorzata Truchan-Graczyk, Denis Caillot, Jean-Luc Harousseau, Serge Bologna, Chantal Himberlin, Denis Guyotat, Christian Berthou, Philippe Casassus, Laurence Baranger, Marie-Christine Béné, Norbert Ifrah, Emmanuel Gyan

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An early thymic precursor phenotype predicts outcome exclusively in HOXA-overexpressing adult T-cell acute lymphoblastic leukemia: a Group for Research in Adult Acute Lymphoblastic... by Jonathan Bond, Tony Marchand, Aurore Touzart, Agata Cieslak, Amélie Trinquand, Laurent Sutton, Isabelle Radford-Weiss, Ludovic Lhermitte, Salvatore Spicuglia, Hervé Dombret, Elizabeth Macintyre, Norbert Ifrah, Jean-François Hamel, Vahid Asnafi

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Low level CpG island promoter methylation predicts a poor outcome in adult T-cell acute lymphoblastic leukemia by Aurore Touzart, Nicolas Boissel, Mohamed Belhocine, Charlotte Smith, Carlos Graux, Mehdi Latiri, Ludovic Lhermitte, Eve-Lyne Mathieu, Françoise Huguet, Laurence Lamant, Pierre Ferrier, Norbert Ifrah, Elizabeth Macintyre, Hervé Dombret, Vahid Asnafi, Salvatore Spicuglia

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TET2 mutations in secondary acute myeloid leukemias: a French retrospective study by Olivier Kosmider, Eric Delabesse, Véronique Mansat-De Mas, Pascale Cornillet-Lefebvre, Odile Blanchet, Alain Delmer, Christian Recher, Sophie Raynaud, Didier Bouscary, Franck Viguié, Catherine Lacombe, Olivier A. Bernard, Norbert Ifrah, François Dreyfus, Michaëla Fontenay

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P321: TNF-MEDIATED CELL DEATH: AN ACTIONABLE TARGET FOR IMMUNOTHERAPY IN T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA by Marie-Emilie Dourthe, Etienne Lengline, Guillaume Charbonnier, Mehdi Latiri, Chaimae Saji, Agata Cieslak, Mathieu Simonin, Norbert Ifrah, Hervé Dombret, Olivier Hermine, Nicolas Boissel, André Baruchel, Jacques Ghysdael, Elizabeth Macintyre, Christine Tran-Quang, Guillaume Andrieu, Vahid Asnafi

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Clinical and biological features of PTPN2-deleted adult and pediatric T-cell acute lymphoblastic leukemia by Marion Alcantara, Mathieu Simonin, Ludovic Lhermitte, Aurore Touzart, Marie Emilie Dourthe, Mehdi Latiri, Nathalie Grardel, Jean Michel Cayuela, Yves Chalandon, Carlos Graux, Hervé Dombret, Norbert Ifrah, Arnaud Petit, Elizabeth Macintyre, André Baruchel, Nicolas Boissel, Vahid Asnafi

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High levels of CD34+CD38low/−CD123+ blasts are predictive of an adverse outcome in acute myeloid leukemia: a Groupe Ouest-Est des Leucémies Aiguës et Maladies du Sang (GOELAMS) stu... by François Vergez, Alexa S. Green, Jerome Tamburini, Jean-Emmanuel Sarry, Baptiste Gaillard, Pascale Cornillet-Lefebvre, Melanie Pannetier, Aymeric Neyret, Nicolas Chapuis, Norbert Ifrah, François Dreyfus, Stéphane Manenti, Cecile Demur, Eric Delabesse, Catherine Lacombe, Patrick Mayeux, Didier Bouscary, Christian Recher, Valerie Bardet

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DNMT3A mutation is associated with increased age and adverse outcome in adult T-cell acute lymphoblastic leukemia by Jonathan Bond, Aurore Touzart, Stéphane Leprêtre, Carlos Graux, Mario Bargetzi, Ludovic Lhermitte, Guillaume Hypolite, Thibaut Leguay, Yosr Hicheri, Gaëlle Guillerm, Karin Bilger, Véronique Lhéritier, Mathilde Hunault, Françoise Huguet, Yves Chalandon, Norbert Ifrah, Elizabeth Macintyre, Hervé Dombret, Vahid Asnafi, Nicolas Boissel

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TET2 gene mutation is a frequent and adverse event in chronic myelomonocytic leukemia by Olivier Kosmider, Véronique Gelsi-Boyer, Marion Ciudad, Cindy Racoeur, Valérie Jooste, Norbert Vey, Bruno Quesnel, Pierre Fenaux, Jean-Noël Bastie, Odile Beyne-Rauzy, Aspasia Stamatoulas, François Dreyfus, Norbert Ifrah, Stéphane de Botton, William Vainchenker, Oliver A. Bernard, Daniel Birnbaum, Michaëla Fontenay, Eric Solary

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Adverse prognostic significance of CD20 expression in adults with Philadelphia chromosome-negative B-cell precursor acute lymphoblastic leukemia by Sébastien Maury, Françoise Huguet, Thibaut Leguay, Francis Lacombe, Marc Maynadié, Sandrine Girard, Adrienne de Labarthe, Emilienne Kuhlein, Emmanuel Raffoux, Xavier Thomas, Patrice Chevallier, Agnès Buzyn, André Delannoy, Yves Chalandon, Jean-Paul Vernant, Philippe Rousselot, Elizabeth Macintyre, Norbert Ifrah, Hervé Dombret, Marie-Christine Béné

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Harnessing the MYB-dependent TAL1 5’super-enhancer for targeted therapy in T-ALL by Charlotte Smith, Aurore Touzart, Mathieu Simonin, Christine Tran-Quang, Guillaume Hypolite, Mehdi Latiri, Guillaume P. Andrieu, Estelle Balducci, Marie-Émilie Dourthe, Ashish Goyal, Françoise Huguet, Arnaud Petit, Norbert Ifrah, André Baruchel, Hervé Dombret, Elizabeth Macintyre, Christoph Plass, Jacques Ghysdael, Nicolas Boissel, Vahid Asnafi

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Mutations in TP53 are exclusively associated with del(17p) in multiple myeloma by Laurence Lodé, Marion Eveillard, Valérie Trichet, Thierry Soussi, Soraya Wuillème, Steven Richebourg, Florence Magrangeas, Norbert Ifrah, Loïc Campion, Catherine Traullé, François Guilhot, Denis Caillot, Gérald Marit, Claire Mathiot, Thierry Facon, Michel Attal, Jean-Luc Harousseau, Philippe Moreau, Stéphane Minvielle, Hervé Avet-Loiseau

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TREC mediated oncogenesis in human immature T lymphoid malignancies preferentially involves ZFP36L2 by Estelle Balducci, Thomas Steimlé, Charlotte Smith, Patrick Villarese, Mélanie Feroul, Dominique Payet-Bornet, Sophie Kaltenbach, Lucile Couronné, Ludovic Lhermitte, Aurore Touzart, Marie-Emilie Dourthe, Mathieu Simonin, André Baruchel, Hervé Dombret, Norbert Ifrah, Nicolas Boissel, Bertrand Nadel, Elizabeth Macintyre, Agata Cieslak, Vahid Asnafi

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