Norman Sharpless

Sharpless in 2019 Norman Edward "Ned" Sharpless (born September 20, 1966) is the previous Director of the National Cancer Institute (NCI). Before that, Sharpless was Professor of Medicine and Genetics Chair, Director of University of North Carolina UNC Lineberger Comprehensive Cancer Center, Molecular Therapeutics, Wellcome Distinguished Professorship in Cancer Research.

Sharpless was named to head the NCI on June 10, 2017, and took office on October 17, 2017. Sharpless also served as Acting Commissioner of the Food and Drugs from April 5, 2019 until November 1, 2019, after which he returned to the NCI. He stepped down from the post at the end of April 2022. Provided by Wikipedia
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  1. 1
    Expression of linear and novel circular forms of an INK4/ARF-associated non-coding RNA correlates with atherosclerosis risk.

    Expression of linear and novel circular forms of an INK4/ARF-associated non-coding RNA correlates with atherosclerosis risk. by Christin E Burd, William R Jeck, Yan Liu, Hanna K Sanoff, Zefeng Wang, Norman E Sharpless

    Published 2010-12-01
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  2. 2
    Chemotherapy and Stem Cell Transplantation Increase p16INK4a Expression, a Biomarker of T-cell Aging

    Chemotherapy and Stem Cell Transplantation Increase p16INK4a Expression, a Biomarker of T-cell Aging by William A. Wood, Janakiraman Krishnamurthy, Natalia Mitin, Chad Torrice, Joel S. Parker, Anna C. Snavely, Thomas C. Shea, Jonathan S. Serody, Norman E. Sharpless

    Published 2016-09-01
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  3. 3
    INK4/ARF transcript expression is associated with chromosome 9p21 variants linked to atherosclerosis.

    INK4/ARF transcript expression is associated with chromosome 9p21 variants linked to atherosclerosis. by Yan Liu, Hanna K Sanoff, Hyunsoon Cho, Christin E Burd, Chad Torrice, Karen L Mohlke, Joseph G Ibrahim, Nancy E Thomas, Norman E Sharpless

    Published 2009-01-01
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  4. 4
    The LKB1 tumor suppressor as a biomarker in mouse and human tissues.

    The LKB1 tumor suppressor as a biomarker in mouse and human tissues. by Yuji Nakada, Thomas G Stewart, Christopher G Peña, Song Zhang, Ni Zhao, Nabeel Bardeesy, Norman E Sharpless, Kwok-Kin Wong, D Neil Hayes, Diego H Castrillon

    Published 2013-01-01
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  5. 5
    Concentrations of Pro-Inflammatory Cytokines Are Not Associated with Senescence Marker p16INK4a or Predictive of Intracellular Emtricitabine/Tenofovir Metabolite and Endogenous Nucleotide Exposures in Adults with HIV Infection.

    Concentrations of Pro-Inflammatory Cytokines Are Not Associated with Senescence Marker p16INK4a or Predictive of Intracellular Emtricitabine/Tenofovir Metabolite and Endogenous Nuc... by Brian M Maas, Owen Francis, Katie R Mollan, Cynthia Lee, Mackenzie L Cottrell, Heather M A Prince, Craig Sykes, Christine Trezza, Chad Torrice, Nicole White, Stephanie Malone, Michael G Hudgens, Norman E Sharpless, Julie B Dumond

    Published 2016-01-01
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  6. 6
    Somatic LKB1 mutations promote cervical cancer progression.

    Somatic LKB1 mutations promote cervical cancer progression. by Shana N Wingo, Teresa D Gallardo, Esra A Akbay, Mei-Chi Liang, Cristina M Contreras, Todd Boren, Takeshi Shimamura, David S Miller, Norman E Sharpless, Nabeel Bardeesy, David J Kwiatkowski, John O Schorge, Kwok-Kin Wong, Diego H Castrillon

    Published 2009-01-01
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  7. 7
    Combined Targeted DNA Sequencing in Non-Small Cell Lung Cancer (NSCLC) Using UNCseq and NGScopy, and RNA Sequencing Using UNCqeR for the Detection of Genetic Aberrations in NSCLC.

    Combined Targeted DNA Sequencing in Non-Small Cell Lung Cancer (NSCLC) Using UNCseq and NGScopy, and RNA Sequencing Using UNCqeR for the Detection of Genetic Aberrations in NSCLC. by Xiaobei Zhao, Anyou Wang, Vonn Walter, Nirali M Patel, David A Eberhard, Michele C Hayward, Ashley H Salazar, Heejoon Jo, Matthew G Soloway, Matthew D Wilkerson, Joel S Parker, Xiaoying Yin, Guosheng Zhang, Marni B Siegel, Gary B Rosson, H Shelton Earp, Norman E Sharpless, Margaret L Gulley, Karen E Weck, D Neil Hayes, Stergios J Moschos

    Published 2015-01-01
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  8. 8
    Lkb1 inactivation drives lung cancer lineage switching governed by Polycomb Repressive Complex 2

    Lkb1 inactivation drives lung cancer lineage switching governed by Polycomb Repressive Complex 2 by Haikuo Zhang, Christine Fillmore Brainson, Shohei Koyama, Amanda J. Redig, Ting Chen, Shuai Li, Manav Gupta, Carolina Garcia-de-Alba, Margherita Paschini, Grit S. Herter-Sprie, Gang Lu, Xin Zhang, Bryan P. Marsh, Stephanie J. Tuminello, Chunxiao Xu, Zhao Chen, Xiaoen Wang, Esra A. Akbay, Mei Zheng, Sangeetha Palakurthi, Lynette M. Sholl, Anil K. Rustgi, David J. Kwiatkowski, J Alan Diehl, Adam J. Bass, Norman E. Sharpless, Glenn Dranoff, Peter S. Hammerman, Hongbin Ji, Nabeel Bardeesy, Dieter Saur, Hideo Watanabe, Carla F. Kim, Kwok-Kin Wong

    Published 2017-04-01
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  9. 9
    Erratum: Lkb1 inactivation drives lung cancer lineage switching governed by Polycomb Repressive Complex 2

    Erratum: Lkb1 inactivation drives lung cancer lineage switching governed by Polycomb Repressive Complex 2 by Haikuo Zhang, Christine Fillmore Brainson, Shohei Koyama, Amanda J. Redig, Ting Chen, Shuai Li, Manav Gupta, Carolina Garcia-de-Alba, Margherita Paschini, Grit S. Herter-Sprie, Gang Lu, Xin Zhang, Bryan P Marsh, Stephanie J. Tuminello, Chunxiao Xu, Zhao Chen, Xiaoen Wang, Esra A. Akbay, Mei Zheng, Sangeetha Palakurthi, Lynette M. Sholl, Anil K. Rustgi, David J. Kwiatkowski, J. Alan Diehl, Adam J. Bass, Norman E. Sharpless, Glenn Dranoff, Peter S. Hammerman, Hongbin Ji, Nabeel Bardeesy, Dieter Saur, Hideo Watanabe, Carla F. Kim, Kwok-Kin Wong

    Published 2017-06-01
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  10. 10
    The Prognostic Significance of Low-Frequency Somatic Mutations in Metastatic Cutaneous Melanoma

    The Prognostic Significance of Low-Frequency Somatic Mutations in Metastatic Cutaneous Melanoma by Xiaobei Zhao, Paul Little, Alan P. Hoyle, Guillaume J. Pegna, Michele C. Hayward, Anastasia Ivanova, Anastasia Ivanova, Joel S. Parker, David L. Marron, Matthew G. Soloway, Heejoon Jo, Ashley H. Salazar, Michael P. Papakonstantinou, Deeanna M. Bouchard, Stuart R. Jefferys, Katherine A. Hoadley, David W. Ollila, David W. Ollila, David W. Ollila, Jill S. Frank, Jill S. Frank, Nancy E. Thomas, Nancy E. Thomas, Nancy E. Thomas, Paul B. Googe, Paul B. Googe, Paul B. Googe, Ashley J. Ezzell, Frances A. Collichio, Frances A. Collichio, Frances A. Collichio, Carrie B. Lee, Carrie B. Lee, Carrie B. Lee, H. Shelton Earp, Norman E. Sharpless, Willy Hugo, James S. Wilmott, Camelia Quek, Nicola Waddell, Peter A. Johansson, John F. Thompson, Nicholas K. Hayward, Graham J. Mann, Roger S. Lo, Douglas B. Johnson, Richard A. Scolyer, D. Neil Hayes, D. Neil Hayes, Stergios J. Moschos, Stergios J. Moschos, Stergios J. Moschos

    Published 2019-01-01
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