Repurposing of KLF5 activates a cell cycle signature during the progression from a precursor state to oesophageal adenocarcinoma by Connor Rogerson, Samuel Ogden, Edward Britton, The OCCAMS Consortium, Yeng Ang, Andrew D Sharrocks

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eRNA profiling uncovers the enhancer landscape of oesophageal adenocarcinoma and reveals new deregulated pathways by Ibrahim Ahmed, Shen-Hsi Yang, Samuel Ogden, Wei Zhang, Yaoyong Li, The OCCAMs consortium, Andrew D Sharrocks

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Open chromatin profiling identifies AP1 as a transcriptional regulator in oesophageal adenocarcinoma. by Edward Britton, Connor Rogerson, Shaveta Mehta, Yaoyong Li, Xiaodun Li, OCCAMS consortium, Rebecca C Fitzgerald, Yeng S Ang, Andrew D Sharrocks

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Multicentre cohort study to define and validate pathological assessment of response to neoadjuvant therapy in oesophagogastric adenocarcinoma by Noble, F, Lloyd, MA, Turkington, R, Griffiths, E, O'Donovan, M, O'Neill, JR, Mercer, S, Parsons, SL, Fitzgerald, RC, Underwood, TJ, Occams Consortium

Impact of mutations in Toll-like receptor pathway genes on esophageal carcinogenesis. by Daffolyn Rachael Fels Elliott, Juliane Perner, Xiaodun Li, Martyn F Symmons, Brett Verstak, Matthew Eldridge, Lawrence Bower, Maria O'Donovan, Nick J Gay, OCCAMS Consortium, Rebecca C Fitzgerald

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Mutational signature dynamics shaping the evolution of oesophageal adenocarcinoma by Sujath Abbas, Oriol Pich, Ginny Devonshire, Shahriar A. Zamani, Annalise Katz-Summercorn, Sarah Killcoyne, Calvin Cheah, Barbara Nutzinger, Nicola Grehan, Nuria Lopez-Bigas, OCCAMS Consortium, Rebecca C. Fitzgerald, Maria Secrier

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Patient-specific cancer genes contribute to recurrently perturbed pathways and establish therapeutic vulnerabilities in esophageal adenocarcinoma by Thanos P. Mourikis, Lorena Benedetti, Elizabeth Foxall, Damjan Temelkovski, Joel Nulsen, Juliane Perner, Matteo Cereda, Jesper Lagergren, Michael Howell, Christopher Yau, Rebecca C. Fitzgerald, Paola Scaffidi, The Oesophageal Cancer Clinical and Molecular Stratification (OCCAMS) Consortium, Francesca D. Ciccarelli

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The landscape of selection in 551 esophageal adenocarcinomas defines genomic biomarkers for the clinic by Frankell, AM, Jammula, S, Li, X, Contino, G, Killcoyne, S, Abbas, S, Perner, J, Bower, L, Devonshire, G, Ococks, E, Grehan, N, Mok, J, O'Donovan, M, Macrae, S, Eldridge, MD, Tavaré, S, Oesophageal Cancer Clinical And Molecular Stratification (OCCAMS) Consortium, Fitzgerald, RC, Crichton, C

Rearrangement processes and structural variations show evidence of selection in oesophageal adenocarcinomas by Alvin Wei Tian Ng, Gianmarco Contino, Sarah Killcoyne, Ginny Devonshire, Ray Hsu, Sujath Abbas, Jing Su, Aisling M. Redmond, Jamie M. J. Weaver, Matthew D. Eldridge, Simon Tavaré, Oesophageal Cancer Clinical and Molecular Stratification (OCCAMS) Consortium, Paul A. W. Edwards, Rebecca C. Fitzgerald

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A comparative analysis of whole genome sequencing of esophageal adenocarcinoma pre- and post-chemotherapy by Noorani, A, Bornschein, J, Lynch, A, Secrier, M, Achilleos, A, Eldridge, M, Bower, L, Weaver, J, Crawte, J, Ong, C, Shannon, N, Macrae, S, Grehan, N, Nutzinger, B, O'Donovan, M, Hardwick, R, Tavaré, S, Fitzgerald, R, Oesophageal Cancer Clinical and Molecular Stratification (OCCAMS) Consortium

Mutational signatures in esophageal adenocarcinoma define etiologically distinct subgroups with therapeutic relevance by Secrier, M, Li, X, De Silva, N, Eldridge, MD, Contino, G, Bornschein, J, Macrae, S, Grehan, N, O'Donovan, M, Miremadi, A, Yang, T-P, Bower, L, Chettouh, H, Crawte, J, Galeano-Dalmau, N, Grabowska, A, Saunders, J, Underwood, T, Waddell, N, Barbour, AP, Nutzinger, B, Achilleos, A, Edwards, PAW, Lynch, AG, Tavaré, S, Fitzgerald, RC, Oesophageal Cancer Clinical And Molecular Stratification (Occams) Consortium