Meta-EA: a gene-specific combination of available computational tools for predicting missense variant effects by Panagiotis Katsonis, Olivier Lichtarge

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Evolutionary Action–Machine Learning Model Identifies Candidate Genes Associated With Early‐Onset Coronary Artery Disease by Dillon Shapiro, Kwanghyuk Lee, Jennifer Asmussen, Thomas Bourquard, Olivier Lichtarge

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Codon-level co-occurrences of germline variants and somatic mutations in cancer are rare but often lead to incorrect variant annotation and underestimated impact prediction. by Amanda Koire, Young Won Kim, Jarey Wang, Panagiotis Katsonis, Haijing Jin, Olivier Lichtarge

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The maternal-to-zygotic transition targets actin to promote robustness during morphogenesis. by Liuliu Zheng, Leonardo A Sepúlveda, Rhonald C Lua, Olivier Lichtarge, Ido Golding, Anna Marie Sokac

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De-orphaning the structural proteome through reciprocal comparison of evolutionarily important structural features. by R Matthew Ward, Serkan Erdin, Tuan A Tran, David M Kristensen, Andreas Martin Lisewski, Olivier Lichtarge

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Functional variants identify sex-specific genes and pathways in Alzheimer’s Disease by Thomas Bourquard, Kwanghyuk Lee, Ismael Al-Ramahi, Minh Pham, Dillon Shapiro, Yashwanth Lagisetty, Shirin Soleimani, Samantha Mota, Kevin Wilhelm, Maryam Samieinasab, Young Won Kim, Eunna Huh, Jennifer Asmussen, Panagiotis Katsonis, Juan Botas, Olivier Lichtarge

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Evolutionary action of mutations reveals antimicrobial resistance genes in Escherichia coli by David C. Marciano, Chen Wang, Teng-Kuei Hsu, Thomas Bourquard, Benu Atri, Ralf B. Nehring, Nicholas S. Abel, Elizabeth A. Bowling, Taylor J. Chen, Pamela D. Lurie, Panagiotis Katsonis, Susan M. Rosenberg, Christophe Herman, Olivier Lichtarge

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Real world predictors of response and 24-month survival in high-grade TP53-mutated myeloid neoplasms by Amandeep Kaur, Alexandra E. Rojek, Emily Symes, Mariam T. Nawas, Anand A. Patel, Jay L. Patel, Payal Sojitra, Barina Aqil, Madina Sukhanova, Megan E. McNerney, Leo P. Wu, Aibek Akmatbekov, Jeremy Segal, Melissa Y. Tjota, Sandeep Gurbuxani, Jason X. Cheng, Su-Yeon Yeon, Harini V. Ravisankar, Carrie Fitzpatrick, Angela Lager, Michael W. Drazer, Caner Saygin, Pankhuri Wanjari, Panagiotis Katsonis, Olivier Lichtarge, Jane E. Churpek, Sharmila B. Ghosh, Ami B. Patel, Madhu P. Menon, Daniel A. Arber, Peng Wang, Girish Venkataraman

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Critical assessment of variant prioritization methods for rare disease diagnosis within the rare genomes project by Sarah L. Stenton, Melanie C. O’Leary, Gabrielle Lemire, Grace E. VanNoy, Stephanie DiTroia, Vijay S. Ganesh, Emily Groopman, Emily O’Heir, Brian Mangilog, Ikeoluwa Osei-Owusu, Lynn S. Pais, Jillian Serrano, Moriel Singer-Berk, Ben Weisburd, Michael W. Wilson, Christina Austin-Tse, Marwa Abdelhakim, Azza Althagafi, Giulia Babbi, Riccardo Bellazzi, Samuele Bovo, Maria Giulia Carta, Rita Casadio, Pieter-Jan Coenen, Federica De Paoli, Matteo Floris, Manavalan Gajapathy, Robert Hoehndorf, Julius O. B. Jacobsen, Thomas Joseph, Akash Kamandula, Panagiotis Katsonis, Cyrielle Kint, Olivier Lichtarge, Ivan Limongelli, Yulan Lu, Paolo Magni, Tarun Karthik Kumar Mamidi, Pier Luigi Martelli, Marta Mulargia, Giovanna Nicora, Keith Nykamp, Vikas Pejaver, Yisu Peng, Thi Hong Cam Pham, Maurizio S. Podda, Aditya Rao, Ettore Rizzo, Vangala G. Saipradeep, Castrense Savojardo, Peter Schols, Yang Shen, Naveen Sivadasan, Damian Smedley, Dorian Soru, Rajgopal Srinivasan, Yuanfei Sun, Uma Sunderam, Wuwei Tan, Naina Tiwari, Xiao Wang, Yaqiong Wang, Amanda Williams, Elizabeth A. Worthey, Rujie Yin, Yuning You, Daniel Zeiberg, Susanna Zucca, Constantina Bakolitsa, Steven E. Brenner, Stephanie M. Fullerton, Predrag Radivojac, Heidi L. Rehm, Anne O’Donnell-Luria

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