Editorial: Pattern recognition receptors at the crosstalk between innate and adaptive immune systems and implications for vaccine development by Omar Rossi, Pietro Mastroeni

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Outer membrane vesicles: moving within the intricate labyrinth of assays that can predict risks of reactogenicity in humans by Omar Rossi, Francesco Citiulo, Francesca Mancini

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Setup and Characterization of a High-Throughput Luminescence-Based Serum Bactericidal Assay (L-SBA) to Determine Functionality of Human Sera against <i>Shigella flexneri</i> by Francesca Mancini, Francesca Micoli, Omar Rossi

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OMV Vaccines and the Role of TLR Agonists in Immune Response by Francesca Mancini, Omar Rossi, Francesca Necchi, Francesca Micoli

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Increasing the High Throughput of a Luminescence-Based Serum Bactericidal Assay (L-SBA) by Maria Grazia Aruta, Martina Carducci, Francesca Micoli, Francesca Necchi, Omar Rossi

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Functional assays to evaluate antibody-mediated responses against Shigella: a review by Elena Boero, Giacomo Vezzani, Francesca Micoli, Mariagrazia Pizza, Mariagrazia Pizza, Omar Rossi

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Characterization of Competitive ELISA and Formulated Alhydrogel Competitive ELISA (FAcE) for Direct Quantification of Active Ingredients in GMMA-Based Vaccines by Omar Rossi, Maria Grazia Aruta, Alessandra Acquaviva, Francesca Mancini, Francesca Micoli, Francesca Necchi

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GMMA-Based Vaccines: The Known and The Unknown by Francesca Mancini, Francesca Micoli, Francesca Necchi, Mariagrazia Pizza, Francesco Berlanda Scorza, Omar Rossi

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Development and Characterisation of a Four-Plex Assay to Measure <i>Streptococcus pyogenes</i> Antigen-Specific IgG in Human Sera by Alexander J. Keeley, Martina Carducci, Luisa Massai, Mariagrazia Pizza, Thushan I. de Silva, Danilo G. Moriel, Omar Rossi

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Comparison of Shigella GMMA and glycoconjugate four-component formulations in animals by Roberta Di Benedetto, Roberta Di Benedetto, Francesca Mancini, Valentina Caradonna, Maria Grazia Aruta, Carlo Giannelli, Omar Rossi, Francesca Micoli

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Development of a Monocyte Activation Test as an Alternative to the Rabbit Pyrogen Test for Mono- and Multi-Component <i>Shigella</i> GMMA-Based Vaccines by Danielle Carson, Sophie Myhill, Elena Palmieri, Francesca Necchi, Sjoerd Rijpkema, Francesca Micoli, Ida Karin Nordgren, Omar Rossi, Caroline Vipond

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O-Antigen decorations in Salmonella enterica play a key role in eliciting functional immune responses against heterologous serovars in animal models by Gianmarco Gasperini, Luisa Massai, Daniele De Simone, Maria Michelina Raso, Elena Palmieri, Renzo Alfini, Omar Rossi, Neil Ravenscroft, Michelle M. Kuttel, Francesca Micoli

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Exploring the Role of GMMA Components in the Immunogenicity of a 4-Valent Vaccine against <i>Shigella</i> by Francesca Mancini, Renzo Alfini, Valentina Caradonna, Valentina Monaci, Martina Carducci, Gianmarco Gasperini, Diego Piccioli, Massimiliano Biagini, Carlo Giannelli, Omar Rossi, Mariagrazia Pizza, Francesca Micoli

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Production of a Shigella sonnei Vaccine Based on Generalized Modules for Membrane Antigens (GMMA), 1790GAHB. by Christiane Gerke, Anna Maria Colucci, Carlo Giannelli, Silvia Sanzone, Claudia Giorgina Vitali, Luigi Sollai, Omar Rossi, Laura B Martin, Jochen Auerbach, Vito Di Cioccio, Allan Saul

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Contribution of factor H-Binding protein sequence to the cross-reactivity of meningococcal native outer membrane vesicle vaccines with over-expressed fHbp variant group 1. by Arianna Marini, Omar Rossi, Maria Grazia Aruta, Francesca Micoli, Simona Rondini, Serafina Guadagnuolo, Isabel Delany, Ian R Henderson, Adam F Cunningham, Allan Saul, Calman A MacLennan, Oliver Koeberling

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Dissecting in Vitro the Activation of Human Immune Response Induced by Shigella sonnei GMMA by Serena Tondi, Serena Tondi, Bruna Clemente, Carmen Esposito, Chiara Sammicheli, Simona Tavarini, Laura B. Martin, Omar Rossi, Francesca Micoli, Erika Bartolini, Michela Brazzoli, Cristina Ulivieri, Christoph J. Blohmke, Francesca Schiavetti

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Stability of Outer Membrane Vesicles-Based Vaccines, Identifying the Most Appropriate Methods to Detect Changes in Vaccine Potency by Elena Palmieri, Vanessa Arato, Davide Oldrini, Beatrice Ricchetti, Maria Grazia Aruta, Werner Pansegrau, Sara Marchi, Fabiola Giusti, Ilaria Ferlenghi, Omar Rossi, Renzo Alfini, Carlo Giannelli, Gianmarco Gasperini, Francesca Necchi, Francesca Micoli

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GMMA as an Alternative Carrier for a Glycoconjugate Vaccine against Group A <i>Streptococcus</i> by Elena Palmieri, Zoltán Kis, James Ozanne, Roberta Di Benedetto, Beatrice Ricchetti, Luisa Massai, Martina Carducci, Davide Oldrini, Gianmarco Gasperini, Maria Grazia Aruta, Omar Rossi, Cleo Kontoravdi, Nilay Shah, Fatme Mawas, Francesca Micoli

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Antibodies Elicited by the Shigella sonnei GMMA Vaccine in Adults Trigger Complement-Mediated Serum Bactericidal Activity: Results From a Phase 1 Dose Escalation Trial Followed by... by Francesca Micoli, Omar Rossi, Valentino Conti, Odile Launay, Odile Launay, Antonella Silvia Sciré, Maria Grazia Aruta, Usman Nasir Nakakana, Elisa Marchetti, Rino Rappuoli, Allan Saul, Laura B. Martin, Francesca Necchi, Audino Podda

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Testing a Recombinant Form of Tetanus Toxoid as a Carrier Protein for Glycoconjugate Vaccines by Davide Oldrini, Roberta Di Benedetto, Martina Carducci, Daniele De Simone, Luisa Massai, Renzo Alfini, Barbara Galli, Brunella Brunelli, Amanda Przedpelski, Joseph T. Barbieri, Omar Rossi, Carlo Giannelli, Rino Rappuoli, Francesco Berti, Francesca Micoli

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