Mucosal delivery of a respiratory syncytial virus CTL peptide with enterotoxin-based adjuvants elicits protective, immunopathogenic, and immunoregulatory antiviral CD8+ T cell resp... by Simmons, C, Hussell, T, Sparer, T, Walzl, G, Openshaw, P, Dougan, G

Mucosal delivery of a respiratory syncytial virus ctl peptide with enterotoxin-based adjuvants elicits protective, immunopathogenic, and immunoregulatory antiviral cd8+ t cell resp... by Simmons, C, Hussell, T, Sparer, T, Walzl, G, Openshaw, P, Dougan, G

A potential molecular mechanism for hypersensitivity caused by formalin-inactivated vaccines. by Moghaddam, A, Olszewska, W, Wang, B, Tregoning, J, Helson, R, Sattentau, Q, Openshaw, P

Human microbial challenge: the ultimate animal model. by Pollard, A, Savulescu, J, Oxford, J, Hill, A, Levine, M, Lewis, D, Read, R, Graham, D, Sun, W, Openshaw, P, Gordon, S

Alternative pathway dysregulation in tissues drives sustained complement activation and predicts outcome across the disease course in COVID-19 by Siggins, M, Davies, K, Fellows, R, Thwaites, R, Baillie, K, Semple, M, Openshaw, P, Zelek, W, Harris, CL, Morgan, BP, Dunning, W

A systematic review and meta-analysis of animal studies investigating the relationship between serum antibody, T lymphocytes, and respiratory syncytial virus disease by McGinley, J, Thwaites, R, Brebner, W, Greenan-Barrett, L, Aerssens, J, Öner, D, Bont, L, Wildenbeest, J, Martinón-Torres, F, Nair, H, Pollard, AJ, Openshaw, P, Drysdale, S

Global and regional burden of hospital admissions for pneumonia in older adults: a systematic review and meta-analysis by Shi, T, Denouel, A, Tietjen, AK, Lee, JW, Falsey, AR, Demont, C, Nyawanda, BO, Cai, B, Fuentes, R, Stoszek, SK, Openshaw, P, Campbell, H, Nair, H, Pollard, A, RESCEU Investigators

Outcomes of COVID-19 related hospitalisation among people with HIV in the ISARIC WHO Clinical Characterisation Protocol UK Protocol: prospective observational study by Geretti, AM, Stockdale, AJ, Kelly, SH, Cevik, M, Collins, S, Waters, L, Villa, G, Docherty, A, Harrison, EM, Turtle, L, Openshaw, P, Baillie, JK, Sabin, C, Semple, M, CHASE Study Group

Simultaneous viral whole-genome sequencing and differential expression profiling in respiratory syncytial virus infection of infants by Lin, G-L, Golubchik, T, Drysdale, S, O'Connor, D, Jefferies, K, Brown, A, de Cesare, M, Bonsall, D, Ansari, MA, Aerssens, J, Bont, L, Openshaw, P, Martinón-Torres, F, Bowden, R, Pollard, AJ

Clinical and viral factors associated with disease severity and subsequent wheezing in infants with respiratory syncytial virus infection by McGinley, JP, Lin, GL, Öner, D, Golubchik, T, O'Connor, D, Snape, MD, Gruselle, O, Langedijk, AC, Wildenbeest, J, Openshaw, P, Nair, H, Aerssens, J, Bont, L, Martinón-Torres, F, Drysdale, SB, Pollard, AJ

Acute kidney injury in patients hospitalized with COVID-19 from the ISARIC WHO CCP-UK Study: a prospective, multicentre cohort study by Sullivan, MK, Lees, JS, Drake, TM, Docherty, AB, Oates, G, Hardwick, HE, Russell, CD, Merson, L, Dunning, J, Nguyen-Van-Tam, JS, Openshaw, P, Harrison, EM, Baillie, JK, Semple, MG, Ho, A, Mark, PB

Unveiling the risk period for death after respiratory syncytial virus Illness in young children using a self- controlled case series design by Li, Y, Campbell, H, Nair, H, Reeves, RM, Douglas, A, Meijer, A, Fischer, TK, Heikkinen, T, Giaquinto, C, Swanson, K, Stoszek, S, Leach, A, Demont, C, Gallichan, S, Aerssens, J, Beutels, P, Bont, L, Pollard, A, Openshaw, P, Abram, M, Rosen, B, Molero, E

M1-like monocytes are a major immunological determinant of severity in previously healthy adults with life-threatening influenza. by Cole, S, Dunning, J, Kok, W, Benam, K, Benlahrech, A, Repapi, E, Martinez, F, Drumright, L, Powell, T, Bennett, M, Elderfield, R, Thomas, C, Dong, T, McCauley, J, Liew, F, Taylor, S, Zambon, M, Barclay, W, Cerundolo, V, Openshaw, P, McMichael, A, Ho, L

M1-like monocytes are a major immunological determinant of severity in previously healthy adults with life-threatening influenza. by Cole, S, Dunning, J, Kok, W, Benam, K, Benlahrech, A, Repapi, E, Martinez, F, Drumright, L, Powell, T, Bennett, M, Elderfield, R, Thomas, C, MOSAIC investigators, Dong, T, McCauley, J, Liew, F, Taylor, S, Zambon, M, Barclay, W, Cerundolo, V, Openshaw, P, McMichael, A, Ho, L

Distinct patterns of within-host virus populations between two subgroups of human respiratory syncytial virus by Lin, G-L, Drysdale, SB, Snape, MD, O'Connor, D, Brown, A, MacIntyre-Cockett, G, Mellado-Gomez, E, de Cesare, M, Bonsall, D, Ansari, MA, Öner, D, Aerssens, J, Butler, C, Bont, L, Openshaw, P, Martinón-Torres, F, Nair, H, Bowden, R, Golubchik, T, Pollard, AJ

Evaluation of pragmatic oxygenation measurement as a proxy for Covid-19 severity by Swets, MC, Kerr, S, Scott-Brown, J, Brown, AB, Gupta, R, Millar, JE, Spata, E, McCurrach, F, Bretherick, AD, Docherty, A, Harrison, D, Rowan, K, Young, N, Groeneveld, GH, Dunning, J, Nguyen-Van-Tam, JS, Openshaw, P, Horby, PW, Harrison, E, Staplin, N, Semple, MG, Lone, N, Baillie, JK

Year-to-year variation in attack rates could result in underpowered respiratory syncytial virus vaccine efficacy trials by Billard, MN, Wildenbeest, J, Bont, LJ, Nair, H, McCracken, JP, Oude Rengerink, K, Marie-Noelle Billard, Bont, L, Campbell, H, Beutels, P, Openshaw, P, Pollard, A, Martinon-Torres, F, Heikkinen, T, Meijer, A, Fischer, TK, van den Berge, M, Giaquinto, C, Aerssens, J, Abram, M, Swanson, K, Demont, C, Gallichan, S, Kumar, V, Stoszek, S, Molero, E

Presumed risk factors and biomarkers for severe respiratory syncytial virus disease and related sequelae: Protocol for an observational multicenter, case-control study from the Res... by Jefferies, K, Drysdale, SB, Robinson, H, Clutterbuck, EA, Blackwell, L, McGinley, J, Lin, G-L, Galal, U, Nair, H, Aerssens, J, Öner, D, Langedijk, A, Bont, L, Wildenbeest, JG, Martinon-Torres, F, Rodríguez-Tenreiro Sánchez, C, Nadel, S, Openshaw, P, Thwaites, R, Widjojoatmodjo, M, Zhang, L, Nguyen, TL-A, Giaquinto, C, Giordano, G, Baraldi, E, Pollard, AJ

Open source clinical science for emerging infections. by Dunning, J, Merson, L, Rohde, G, Gao, Z, Semple, MG, Tran, D, Gordon, A, Olliaro, P, Khoo, S, Bruzzone, R, Horby, P, Cobb, J, Longuere, K, Kellam, P, Nichol, A, Brett, S, Everett, D, Walsh, T, Hien, T, Yu, H, Zambon, M, Ruiz-Palacios, G, Lang, T, Akhvlediani, T, Hayden, F, Marshall, J, Webb, S, Angus, D, Shindo, N, van der Werf, S, Openshaw, P, Farrar, J, Carson, G, Baillie, J

A systematic review of clinical practice guidelines for the diagnosis and management of bronchiolitis by Manti, S, Blacow, R, Tse, G, Wilson, T, Lister, M, Cunningham, S, Campbell, A, Nair, H, Reeves, RM, Fernandes, RM, Campbell, H, Campbell, H, Nair, H, Reeves, RM, Douglas, A, Cunningham, S, Fernandes, RM, Meijer, A, Fischer, TK, Heikkinen, T, Giaquinto, C, Knirsch, C, Stoszek, S, Leach, A, Demont, C, Gallichan, S, Aerssens, J, Beutels, P, Bont, L, Pollard, A, Openshaw, P, Hackett, J, Rosen, B, Molero, E