Transcriptional silencing of γ-globin by BCL11A involves long-range interactions and cooperation with SOX6 by Xu, Jian, Sankaran, Vijay G., Ni, Min, Menne, Tobias F., Puram, Rishi Venkata, Kim, Woojin, Orkin, Stuart H.

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A Transient Transgenic RNAi Strategy for Rapid Characterization of Gene Function during Embryonic Development by Bjork, Bryan C., Fujiwara, Yuko, Davis, Shannon W., Qiu, Haiyan, Saunders, Thomas L., Sandy, Peter, Orkin, Stuart H., Camper, Sally A., Beier, David R.

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MicroRNA-15a and -16-1 act via MYB to elevate fetal hemoglobin expression in human trisomy 13 by Sankaran, Vijay G., Menne, Tobias F., Scepanovic, Danilo, Vergilio, Jo-Anne, Ji, Peng, Kim, Jinkuk, Thiru, Prathapan, Orkin, Stuart H., Lander, Eric Steven, Lodish, Harvey F

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Insights into GATA-1 Mediated Gene Activation versus Repression via Genome-wide Chromatin Occupancy Analysis by Yu, Ming, Riva, Laura, Schindler, Yocheved, Moran, Tyler B., Cheng, Yong, Yu, Duonan, Hardison, Ross C., Weiss, Mitchell J., Orkin, Stuart H., Bernstein, Bradley E., Fraenkel, Ernest, Cantor, Alan B.

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Cyclin D3 coordinates the cell cycle during differentiation to regulate erythrocyte size and number by Eng, Jennifer Christina, Sankaran, Vijay G., Ludwig, Leif S., Sicinska, Ewa, Xu, Jian, Bauer, Daniel E., Patterson, Heide Christine, Metcalf, Ryan A., Natkunam, Yasodha, Orkin, Stuart H., Sicinski, Piotr, Lander, Eric Steven, Lodish, Harvey F

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BORIS promotes chromatin regulatory interactions in treatment-resistant cancer cells by Debruyne, David N., Dries, Ruben, Sengupta, Satyaki, Seruggia, Davide, Gao, Yang, Sharma, Bandana, Huang, Hao, Moreau, Lisa, McLane, Michael, Day, Daniel Sindt, Marco, Eugenio, Chen, Ting, Gray, Nathanael S., Wong, Kwok-Kin, Orkin, Stuart H., Yuan, Guo-Cheng, Young, Richard A., George, Rani E.

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BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis by Canver, Matthew C., Smith, Elenoe C., Sher, Falak, Pinello, Luca, Shalem, Ophir, Chen, Diane D., Schupp, Patrick G., Vinjamur, Divya S., Garcia, Sara P., Luc, Sidinh, Kurita, Ryo, Nakamura, Yukio, Fujiwara, Yuko, Maeda, Takahiro, Yuan, Guo-Cheng, Zhang, Feng, Orkin, Stuart H., Bauer, Daniel E., Sanjana, Neville

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The histone demethylase UTX regulates the lineage-specific epigenetic program of invariant natural killer T cells by Beyaz, Semir, Kim, Ji Hyung, Pinello, Luca, Huang, Jialiang, Kerenyi, Marc A, Das, Partha P, Barnitz, R Anthony, Herault, Aurelie, Haining, W Nicholas, Passegue, Emmanuelle, Yuan, Guo-Cheng, Orkin, Stuart H, Winau, Florian, Xifaras, Michael, Dogum, Rizkullah, Yilmaz, Omer, Hu, Yu,M.C.P.Massachusetts Institute of Technology.

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The mTORC1/4E-BP pathway coordinates hemoglobin production with L-leucine availability by Chung, J., Bauer, D. E., Ghamari, A., Nizzi, C. P., Deck, K. M., Kingsley, P. D., Yien, Y. Y., Huston, N. C., Chen, C., Schultz, I. J., Dalton, A. J., Wittig, J. G., Palis, J., Orkin, S. H., Eisenstein, R. S., Cantor, A. B., Paw, B. H., Lodish, Harvey F

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Transcription control by the ENL YEATS domain in acute leukaemia by Erb, Michael A., Scott, Thomas G., Li, Bin E., Xie, Huafeng, Paulk, Joshiawa, Seo, Hyuk-Soo, Souza, Amanda, Roberts, Justin M., Dastjerdi, Shiva, Buckley, Dennis L., Nabet, Behnam, Zeid, Rhamy, Offei-Addo, Nana K., Dhe-Paganon, Sirano, Orkin, Stuart H., Winter, Georg E., Bradner, James E., Sanjana, Neville E, Shalem, Ophir, Zhang, Feng

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Control of human hemoglobin switching by LIN28B-mediated regulation of BCL11A translation by Basak, Anindita, Munschauer, Mathias, Lareau, Caleb A., Montbleau, Kara E., Ulirsch, Jacob C., Hartigan, Christina R., Schenone, Monica, Lian, John, Wang, Yaomei, Huang, Yumin, Wu, Xianfang, Gehrke, Lee, Rice, Charles M., An, Xiuli, Christou, Helen A., Mohandas, Narla, Carr, Steven A., Chen, Jane-Jane, Orkin, Stuart H., Lander, Eric Steven, Sankaran, Vijay G.

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Erythropoietin signaling regulates heme biosynthesis by Chung, Jacky, Wittig, Johannes G, Ghamari, Alireza, Maeda, Manami, Dailey, Tamara A, Bergonia, Hector, Kafina, Martin D, Coughlin, Emma E, Minogue, Catherine E, Hebert, Alexander S, Li, Liangtao, Kaplan, Jerry, Lodish, Harvey F, Bauer, Daniel E, Orkin, Stuart H, Cantor, Alan B, Maeda, Takahiro, Phillips, John D, Coon, Joshua J, Pagliarini, David J, Dailey, Harry A, Paw, Barry H

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Epigenetic memory in induced pluripotent stem cells by Kim, K., Doi, A., Wen, B., Ng, K., Zhao, R., Cahan, Patrick, Kim, J., Aryee, M. J., Ji, H., Ehrlich, L. I. R., Yabuuchi, A., Takeuchi, A., Cunniff, K. C., Hongguang, H., Mckinney-Freeman, S., Naveiras, O., Yoon, T. J., Irizarry, Rafael A., Jung, N., Seita, J., Hanna, Jacob, Murakami, P., Jaenisch, Rudolf, Weissleder, R., Orkin, Stuart H.

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PRC2 Is Required to Maintain Expression of the Maternal Gtl2-Rian-Mirg Locus by Preventing De Novo DNA Methylation in Mouse Embryonic Stem Cells by Das, Partha Pratim, Hendrix, David A., Apostolou, Effie, Buchner, Alice H., Canver, Matthew C., Beyaz, Semir, Ljuboja, Damir, Kuintzle, Rachael, Kim, Woojin, Karnik, Rahul, Shao, Zhen, Xie, Huafeng, Xu, Jian, De Los Angeles, Alejandro, Zhang, Yingying, Choe, Junho, Jun, Don Leong Jia, Shen, Xiaohua, Gregory, Richard I., Daley, George Q., Meissner, Alexander, Kellis, Manolis, Hochedlinger, Konrad, Kim, Jonghwan, Orkin, Stuart H., Hendrix, David A.

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High-fat diet enhances stemness and tumorigenicity of intestinal progenitors by Saadatpour, Assieh, Hong, Sue-Jean, Pinello, Luca, Katz, Yarden, Lamming, Dudley W., Guo, Guoji, Bell, George W., Selig, Martin, Nielsen, G. Petur, Gupta, Nitin, Ferrone, Cristina R., Deshpande, Vikram, Yuan, Guo-Cheng, Orkin, Stuart H., Beyaz, Semir, Mana, Miyeko, Roper, Jatin, Kedrin, Dmitriy, Bauer-Rowe, Khristian E., Xifaras, Michael, Akkad, Adam, Arias, Erika, Shinagare, Shweta, Abu-Remaileh, Monther, Dogum, Rizkullah, Sabatini, David, Yilmaz, Omer, Mihaylova, Maria M.

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Hypoxic, glycolytic metabolism is a vulnerability of B-acute lymphoblastic leukemia-initiating cells by Morris, Vivian, Wang, Dahai, Li, Zhiheng, Marion, William, Hughes, Travis, Sousa, Patricia, Harada, Taku, Sui, Shannan Ho, Naumenko, Sergey, Kalfon, Jérémie, Sensharma, Prerana, Falchetti, Marcelo, Vinicius da Silva, Renan, Candelli, Tito, Schneider, Pauline, Margaritis, Thanasis, Holstege, Frank CP, Pikman, Yana, Harris, Marian, Stam, Ronald W, Orkin, Stuart H, Koehler, Angela N, Shalek, Alex K, North, Trista E, Pimkin, Maxim, Daley, George Q, Lummertz da Rocha, Edroaldo, Rowe, R Grant

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Loss of the retinoblastoma binding protein 2 (RBP2) histone demethylase suppresses tumorigenesis in mice lacking Rb1 or Men1 by Lin, Wenchu, Cao, Jian, Liu, Jiayun, Beshiri, Michael L., Fujiwara, Yuko, Francis, Joshua M., Cherniack, Andrew D., Geisen, Christoph, Blair, Lauren P., Zou, Mike R., Shen, Xiaohua, Liu, Zongzhi, Grisanzio, Chiara, Watanabe, Hideo, Minamishima, Yoji Andrew, Zhang, Qing, Kulkarni, Rohit N., Signoretti, Sabina, Rodig, Scott J., Bronson, Roderick T., Orkin, Stuart H., Tuck, David P., Benevolenskaya, Elizaveta V., Kawamori, Dan, Meyerson, Matthew L., Kaelin Jr., William G., Qin, Yan

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