Imaging of atherosclerosis. 由 Owen, DR, Lindsay, A, Choudhury, R, Fayad, Z

The use of contrast enhanced ultrasound in carotid arterial disease. 由 Shalhoub, J, Owen, DR, Gauthier, T, Monaco, C, Leen, E, Davies, A

Late-phase contrast-enhanced ultrasound reflects biological features of instability in human carotid atherosclerosis. 由 Shalhoub, J, Monaco, C, Owen, DR, Gauthier, T, Thapar, A, Leen, E, Davies, A

Predicting the in vivo performance of TSPO PET radioligands using a biomathematical modelling approach 由 Guo, Q, Owen, DR, Bennacef, I, Rabiner, E, Parker, C, Brady, M, Gunn, R

Pro-inflammatory activation of primary microglia and macrophages increases 18 kDa translocator protein expression in rodents but not humans. 由 Owen, DR, Narayan, N, Wells, L, Healy, L, Smyth, E, Rabiner, EA, Galloway, D, Williams, JB, Lehr, J, Mandhair, H, Peferoen, LA, Taylor, PC, Amor, S, Antel, JP, Matthews, PM, Moore, CS

PFI-1, a highly selective protein interaction inhibitor, targeting BET Bromodomains. 由 Picaud, S, Da Costa, D, Thanasopoulou, A, Filippakopoulos, P, Fish, P, Philpott, M, Fedorov, O, Brennan, P, Bunnage, M, Owen, DR, Bradner, J, Taniere, P, O'Sullivan, B, Müller, S, Schwaller, J, Stankovic, T, Knapp, S

Identification of a chemical probe for bromo and extra C-terminal bromodomain inhibition through optimization of a fragment-derived hit. 由 Fish, P, Filippakopoulos, P, Bish, G, Brennan, P, Bunnage, M, Cook, A, Federov, O, Gerstenberger, B, Jones, H, Knapp, S, Marsden, B, Nocka, K, Owen, DR, Philpott, M, Picaud, S, Primiano, M, Ralph, M, Sciammetta, N, Trzupek, J

A data science roadmap for open science organizations engaged in early-stage drug discovery 由 Edfeldt, K, Edwards, AM, Engkvist, O, Günther, J, Hartley, M, Hulcoop, DG, Leach, AR, Marsden, BD, Menge, A, Misquitta, L, Müller, S, Owen, DR, Schütt, KT, Skelton, N, Steffen, A, Tropsha, A, Vernet, E, Wang, Y, Wellnitz, J, Willson, TM, Clevert, D, Haibe-Kains, B, Schiavone, LH, Schapira, M

Identification of a chemical probe for family VIII bromodomains through optimization of a fragment hit 由 Gerstenberger, BS, Trzupek, JD, Tallant, C, Fedorov, O, Filippakopoulos, P, Brennan, PE, Fedele, V, Martin, S, Picaud, S, Rogers, C, Parikh, M, Taylor, A, Samas, B, O'Mahony, A, Berg, E, Pallares, G, Torrey, AD, Treiber, DK, Samardjiev, IJ, Nasipak, BT, Padilla-Benavides, T, Wu, Q, Imbalzano, AN, Nickerson, JA, Bunnage, ME, Müller, S, Knapp, S, Owen, DR

Selective targeting of bromodomains of the bromodomain-PHD fingers family impairs osteoclast differentiation 由 Meier, JC, Tallant, C, Fedorov, O, Witwicka, H, Hwang, SY, van Stiphout, RG, Lambert, JP, Rogers, C, Yapp, C, Gerstenberger, BS, Fedele, V, Savitsky, P, Heidenreich, D, Daniels, DL, Owen, DR, Fish, PV, Igoe, NM, Bayle, ED, Haendler, B, Oppermann, UCT, Buffa, F, Brennan, PE, Müller, S, Gingras, AC, Odgren, PR, Birnbaum, MJ, Knapp, S

Target 2035 - an update on private sector contributions 由 Ackloo, S, Antolin, AA, Bartolome, JM, Beck, H, Bullock, A, Betz, UAK, Böttcher, J, Brown, PJ, Chaturvedi, M, Crisp, A, Daniels, D, Dreher, J, Edfeldt, K, Edwards, AM, Egner, U, Elkins, J, Fischer, C, Glendorf, T, Goldberg, S, Hartung, IV, Hillisch, A, Homan, E, Knapp, S, Köster, M, Krämer, O, Llaveria, J, Lessel, U, Lindemann, S, Linderoth, L, Matsui, H, Michel, M, Montel, F, Mueller-Fahrnow, A, Müller, S, Owen, DR, Saikatendu, KS, Santhakumar, V, Sanderson, W, Scholten, C, Schapira, M, Sharma, S, Shireman, B, Sundström, M, Todd, MH, Tredup, C, Venable, J, Willson, TM, Arrowsmith, CH

Target 2035-update on the quest for a probe for every protein 由 Mueller, S, Ackloo, S, Al Chawaf, A, Al-Lazikani, B, Antolin, A, Baell, JB, Beck, H, Beedie, S, Betz, UAK, Bezerra, GA, Brennan, PE, Bullock, AN, Brown, D, Brown, PJ, Carter, AJ, Chaikuad, A, Chaineau, M, Ciulli, A, Collins, I, Dreher, J, Drewry, D, Edfeldt, K, Edwards, AM, Egner, U, Frye, SV, Fuchs, SM, Hall, MD, Hartung, IV, Hillisch, A, Hitchcock, SH, Homan, E, Kannan, N, Kiefer, JR, Knapp, S, Kostic, M, Kubicek, S, Leach, AR, Lindemann, S, Marsden, BD, Matsui, H, Meier, JL, Merk, D, Michel, M, Morgan, MR, Mueller-Fahrnow, A, Owen, DR, Perry, BG, Rosenberg, SH, Saikatendu, KS, Schapira, M