Replacement of traditional prothrombin time monitoring with the new Fiix prothrombin time increases the efficacy of warfarin without increasing bleeding. A review article by Pall T. Onundarson, Ragnar Palsson, Daniel M. Witt, Brynja R. Gudmundsdottir

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Comparison of medication adherence to different oral anticoagulants: population-based cohort study by Einar S Björnsson, Sigrun H Lund, Arnar B Ingason, Jóhann P Hreinsson, Arnar S Ágústsson, Edward Rumba, Daníel A Pálsson, Indriði E Reynisson, Brynja R Guðmundsdóttir, Páll T Önundarson

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P900: INVOLVED/UNINVOLVED SERUM FREE LIGHT CHAIN RATIO IS A STRONGER PREDICTOR OF DIAGNOSTIC/RISK FACTORS IN LIGHT CHAIN COMPARED TO HEAVY CHAIN MONOCLONAL GAMMOPATHIES by Jon Thorir Oskarsson, Sigrún Þorsteinsdóttir, Sæmundur Rögnvaldsson, Guðrún Ásta Sigurðardóttir, Ásdís Rósa Þórðardóttir, Gauti Kjartan Gíslason, Andri Ólafsson, Jón Kristinn Sigurðsson, Elías Eyþórsson, Ásbjörn Jónsson, Brynjar Viðarsson, Páll Torfi Önundarson, Bjarni Agnar Agnarsson, Robert Palmason, Margrét Sigurðardóttir, Ingunn Þorsteinsdóttir, Ísleifur Ólafsson, Stephen Harding, Brian Durie, Thorvardur Jon Love, Sigurdur Yngvi Kristinsson

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Defining new reference intervals for serum free light chains in individuals with chronic kidney disease: Results of the iStopMM study by Thorir Einarsson Long, Olafur Skuli Indridason, Runolfur Palsson, Sæmundur Rognvaldsson, Thorvardur Jon Love, Sigrun Thorsteinsdottir, Ingigerdur Solveig Sverrisdottir, Brynjar Vidarsson, Pall Torfi Onundarson, Bjarni Agnar Agnarsson, Margret Sigurdardottir, Ingunn Thorsteinsdottir, Isleifur Olafsson, Asdis Rosa Thordardottir, Elias Eythorsson, Asbjorn Jonsson, Gauti Gislason, Andri Olafsson, Hlif Steingrimsdottir, Malin Hultcrantz, Brian G. M. Durie, Stephen Harding, Ola Landgren, Sigurdur Yngvi Kristinsson

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Determining hemodilution in diagnostic bone marrow aspirated samples in plasma cell disorders by next-generation flow cytometry: Proposal for a bone marrow quality index by Jón Þórir Óskarsson, Sæmundur Rögnvaldsson, Sigrun Thorsteinsdottir, Thor Aspelund, Steinar Bragi Gunnarsson, Guðlaug Katrín Hákonardóttir, Guðrún Ásta Sigurðardóttir, Ásdís Rósa Þórðardóttir, Gauti Kjartan Gíslason, Andri Ólafsson, Jón Kristinn Sigurðsson, Elías Eyþórsson, Ásbjörn Jónsson, Brynjar Viðarsson, Páll Torfi Önundarson, Bjarni A. Agnarsson, Róbert Pálmason, Margrét Sigurðardóttir, Ingunn Þorsteinsdóttir, Ísleifur Ólafsson, Stephen Harding, Juan Flores-Montero, Alberto Orfao, Brian G. M. Durie, Thorvardur Jon Love, Sigurdur Yngvi Kristinsson

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P894: INFECTION RISK BEFORE DIAGNOSIS OF MONOCLONAL GAMMOPATHY OF UNDETERMINED SIGNIFICANCE: RESULTS FROM THE SCREENED POPULATION-BASED ISTOPMM STUDY by Marina Ros Levy, Sæmundur Rögnvaldsson, Alessandro Gasparini, Elías Eyþórsson, Guðrún Ásta Sigurðardóttir, Brynjar Viðarsson, Páll Torfi Önundarson, Bjarni Agnar Agnarsson, Margrét Sigurðardóttir, Ísleifur Ólafsson, Ingunn Þorsteinsdóttir, Ásdís Rósa Þórðardóttir, Ásbjörn Jónsson, Thor Aspelun, Gauti Kjartan Gíslason, Andri Ólafsson, Jón Kristinn Sigurðsson, Ingigerdur Solveig Sverrisdottir, Þórir Einarsson Long, Malin Hultcrantz, Brian Durie, Stephen Harding, Hannah Bower, C. Ola Landgren, Thorvardur Jon Love, Sigurdur Yngvi Kristinsson, Sigrún Þorsteinsdóttir

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P950: PRIOR CANCER AND RISK OF MONOCLONAL GAMMOPATHY OF UNDETERMINED SIGNIFICANCE (MGUS): A POPULATION-BASED STUDY IN ICELAND AND SWEDEN by Sæmundur Rögnvaldsson, Sigrún Þorsteinsdóttir, Elisavet Syriopoulou, Ingigerdur Solveig Sverrisdottir, Ingemar Turesson, Elías Eyþórsson, Guðrún Ásta Sigurðardóttir, Brynjar Viðarsson, Páll Torfi Önundarson, Bjarni Agnar Agnarsson, Margrét Sigurðadóttir, Ísleifur Ólafsson, Ingunn Þorsteinsdóttir, Robert Palmason, Jon Thorir Oskarsson, Ásdís Rósa Þórðardóttir, Ásbjörn Jónsson, Runólfur Pálsson, Ólafur Skúli Indriðason, Thor Aspelun, Hannah Bower, Gauti Kjartan Gíslason, Andri Ólafsson, Jón Kristinn Sigurðsson, Þórir Einarsson Long, Malin Hultcrantz, Brian Durie, Stephen Harding, Magnus Bjorkholm, C. Ola Landgren, Thorvardur Jon Love, Sigurdur Yngvi Kristinsson

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Genetic architecture of band neutrophil fraction in Iceland by Gudjon R. Oskarsson, Magnus K. Magnusson, Asmundur Oddsson, Brynjar O. Jensson, Run Fridriksdottir, Gudny A. Arnadottir, Hildigunnur Katrinardottir, Solvi Rognvaldsson, Gisli H. Halldorsson, Gardar Sveinbjornsson, Erna V. Ivarsdottir, Lilja Stefansdottir, Egil Ferkingstad, Kristjan Norland, Vinicius Tragante, Jona Saemundsdottir, Aslaug Jonasdottir, Adalbjorg Jonasdottir, Svanhvit Sigurjonsdottir, Karen O. Petursdottir, Olafur B. Davidsson, Thorunn Rafnar, Hilma Holm, Isleifur Olafsson, Pall T. Onundarson, Brynjar Vidarsson, Olof Sigurdardottir, Gisli Masson, Daniel F. Gudbjartsson, Ingileif Jonsdottir, Gudmundur L. Norddahl, Unnur Thorsteinsdottir, Patrick Sulem, Kari Stefansson

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Eighty-eight variants highlight the role of T cell regulation and airway remodeling in asthma pathogenesis by Thorunn A. Olafsdottir, Fannar Theodors, Kristbjorg Bjarnadottir, Unnur Steina Bjornsdottir, Arna B. Agustsdottir, Olafur A. Stefansson, Erna V. Ivarsdottir, Jon K. Sigurdsson, Stefania Benonisdottir, Gudmundur I. Eyjolfsson, David Gislason, Thorarinn Gislason, Steinunn Guðmundsdóttir, Arnaldur Gylfason, Bjarni V. Halldorsson, Gisli H. Halldorsson, Thorhildur Juliusdottir, Anna M. Kristinsdottir, Dora Ludviksdottir, Bjorn R. Ludviksson, Gisli Masson, Kristjan Norland, Pall T. Onundarson, Isleifur Olafsson, Olof Sigurdardottir, Lilja Stefansdottir, Gardar Sveinbjornsson, Vinicius Tragante, Daniel F. Gudbjartsson, Gudmar Thorleifsson, Patrick Sulem, Unnur Thorsteinsdottir, Gudmundur L. Norddahl, Ingileif Jonsdottir, Kari Stefansson

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Iceland screens, treats, or prevents multiple myeloma (iStopMM): a population-based screening study for monoclonal gammopathy of undetermined significance and randomized controlled... by Sæmundur Rögnvaldsson, Thorvardur Jon Love, Sigrun Thorsteinsdottir, Elín Ruth Reed, Jón Þórir Óskarsson, Íris Pétursdóttir, Guðrún Ásta Sigurðardóttir, Brynjar Viðarsson, Páll Torfi Önundarson, Bjarni A. Agnarsson, Margrét Sigurðardóttir, Ingunn Þorsteinsdóttir, Ísleifur Ólafsson, Ásdís Rósa Þórðardóttir, Elías Eyþórsson, Ásbjörn Jónsson, Andri S. Björnsson, Gunnar Þór Gunnarsson, Runólfur Pálsson, Ólafur Skúli Indriðason, Gauti Kjartan Gíslason, Andri Ólafsson, Guðlaug Katrín Hákonardóttir, Manje Brinkhuis, Sara Lovísa Halldórsdóttir, Tinna Laufey Ásgeirsdóttir, Hlíf Steingrímsdóttir, Ragnar Danielsen, Inga Dröfn Wessman, Petros Kampanis, Malin Hultcrantz, Brian G. M. Durie, Stephen Harding, Ola Landgren, Sigurður Yngvi Kristinsson

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Correction: Iceland screens, treats, or prevents multiple myeloma (iStopMM): a population-based screening study for monoclonal gammopathy of undetermined significance and randomize... by Sæmundur Rögnvaldsson, Thorvardur Jon Love, Sigrun Thorsteinsdottir, Elín Ruth Reed, Jón Þórir Óskarsson, Íris Pétursdóttir, Guðrún Ásta Sigurðardóttir, Brynjar Viðarsson, Páll Torfi Önundarson, Bjarni A. Agnarsson, Margrét Sigurðardóttir, Ingunn Þorsteinsdóttir, Ísleifur Ólafsson, Ásdís Rósa Þórðardóttir, Elías Eyþórsson, Ásbjörn Jónsson, Andri S. Björnsson, Gunnar Þór Gunnarsson, Runólfur Pálsson, Ólafur Skúli Indriðason, Gauti Kjartan Gíslason, Andri Ólafsson, Guðlaug Katrín Hákonardóttir, Manje Brinkhuis, Sara Lovísa Halldórsdóttir, Tinna Laufey Ásgeirsdóttir, Hlíf Steingrímsdóttir, Ragnar Danielsen, Inga Dröfn Wessman, Petros Kampanis, Malin Hultcrantz, Brian G. M. Durie, Stephen Harding, Ola Landgren, Sigurður Yngvi Kristinsson

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Sequence variant affects GCSAML splicing, mast cell specific proteins, and risk of urticaria by Ragnar P. Kristjansson, Gudjon R. Oskarsson, Astros Skuladottir, Asmundur Oddsson, Solvi Rognvaldsson, Gardar Sveinbjornsson, Sigrun H. Lund, Brynjar O. Jensson, Edda L. Styrmisdottir, Gisli H. Halldorsson, Egil Ferkingstad, Grimur Hjorleifsson Eldjarn, Doruk Beyter, Snædis Kristmundsdottir, Kristinn Juliusson, Run Fridriksdottir, Gudny A. Arnadottir, Hildigunnur Katrinardottir, Margret H. Snorradottir, Vinicius Tragante, Lilja Stefansdottir, Erna V. Ivarsdottir, Gyda Bjornsdottir, Bjarni V. Halldorsson, Gudmar Thorleifsson, Bjorn R. Ludviksson, Pall T. Onundarson, Saedis Saevarsdottir, Pall Melsted, Gudmundur L. Norddahl, Unnur S. Bjornsdottir, Thorunn Olafsdottir, Daniel F. Gudbjartsson, Unnur Thorsteinsdottir, Ingileif Jonsdottir, Patrick Sulem, Kari Stefansson

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A rare IL33 loss-of-function mutation reduces blood eosinophil counts and protects from asthma. by Dirk Smith, Hannes Helgason, Patrick Sulem, Unnur Steina Bjornsdottir, Ai Ching Lim, Gardar Sveinbjornsson, Haruki Hasegawa, Michael Brown, Randal R Ketchem, Monica Gavala, Logan Garrett, Adalbjorg Jonasdottir, Aslaug Jonasdottir, Asgeir Sigurdsson, Olafur T Magnusson, Gudmundur I Eyjolfsson, Isleifur Olafsson, Pall Torfi Onundarson, Olof Sigurdardottir, David Gislason, Thorarinn Gislason, Bjorn Runar Ludviksson, Dora Ludviksdottir, H Marike Boezen, Andrea Heinzmann, Marcus Krueger, Celeste Porsbjerg, Tarunveer S Ahluwalia, Johannes Waage, Vibeke Backer, Klaus A Deichmann, Gerard H Koppelman, Klaus Bønnelykke, Hans Bisgaard, Gisli Masson, Unnur Thorsteinsdottir, Daniel F Gudbjartsson, James A Johnston, Ingileif Jonsdottir, Kari Stefansson

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A genome-wide meta-analysis yields 46 new loci associating with biomarkers of iron homeostasis by Steven Bell, Andreas S. Rigas, Magnus K. Magnusson, Egil Ferkingstad, Elias Allara, Gyda Bjornsdottir, Anna Ramond, Erik Sørensen, Gisli H. Halldorsson, Dirk S. Paul, Kristoffer S. Burgdorf, Hannes P. Eggertsson, Joanna M. M. Howson, Lise W. Thørner, Snaedis Kristmundsdottir, William J. Astle, Christian Erikstrup, Jon K. Sigurdsson, Dragana Vuckovic, Khoa M. Dinh, Vinicius Tragante, Praveen Surendran, Ole B. Pedersen, Brynjar Vidarsson, Tao Jiang, Helene M. Paarup, Pall T. Onundarson, Parsa Akbari, Kaspar R. Nielsen, Sigrun H. Lund, Kristinn Juliusson, Magnus I. Magnusson, Michael L. Frigge, Asmundur Oddsson, Isleifur Olafsson, Stephen Kaptoge, Henrik Hjalgrim, Gudmundur Runarsson, Angela M. Wood, Ingileif Jonsdottir, Thomas F. Hansen, Olof Sigurdardottir, Hreinn Stefansson, David Rye, DBDS Genomic Consortium, James E. Peters, David Westergaard, Hilma Holm, Nicole Soranzo, Karina Banasik, Gudmar Thorleifsson, Willem H. Ouwehand, Unnur Thorsteinsdottir, David J. Roberts, Patrick Sulem, Adam S. Butterworth, Daniel F. Gudbjartsson, John Danesh, Søren Brunak, Emanuele Di Angelantonio, Henrik Ullum, Kari Stefansson

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