Designing and analyzing clinical trials with composite outcomes: consideration of possible treatment differences between the individual outcomes. by Janice Pogue, P J Devereaux, Lehana Thabane, Salim Yusuf

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Assessment and implication of prognostic imbalance in randomized controlled trials with a binary outcome--a simulation study. by Rong Chu, Stephen D Walter, Gordon Guyatt, P J Devereaux, Michael Walsh, Kristian Thorlund, Lehana Thabane

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Conversion between B-type natriuretic peptide and N-terminal pro B-type natriuretic peptide in perioperative risk assessment: protocol for a prospective cohort study by P J Devereaux, Ben King, Pavel S Roshanov, Jordan Leitch, Joel Parlow, Deborah DuMerton, Taryn Davidson

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Simple compared to covariate-constrained randomization methods in balancing baseline characteristics: a case study of randomly allocating 72 hemodialysis centers in a cluster trial by Ahmed A. Al-Jaishi, Stephanie N. Dixon, Eric McArthur, P. J. Devereaux, Lehana Thabane, Amit X. Garg

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New‐Onset Perioperative Atrial Fibrillation After Coronary Artery Bypass Grafting and Long‐Term Risk of Adverse Events: An Analysis From the CORONARY Trial by David Conen, Michael K. Wang, P. J. Devereaux, Richard Whitlock, William F. McIntyre, Jeff S. Healey, Fei Yuan, Salim Yusuf, Andre Lamy

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Machine learning algorithms to identify cluster randomized trials from MEDLINE and EMBASE by Ahmed A. Al-Jaishi, Monica Taljaard, Melissa D. Al-Jaishi, Sheikh S. Abdullah, Lehana Thabane, P. J. Devereaux, Stephanie N. Dixon, Amit X. Garg

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The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. by Alessandro Liberati, Douglas G Altman, Jennifer Tetzlaff, Cynthia Mulrow, Peter C Gøtzsche, John P A Ioannidis, Mike Clarke, P J Devereaux, Jos Kleijnen, David Moher

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A pragmatic randomized trial evaluating pre-operative aqueous antiseptic skin solutions in open fractures (Aqueous-PREP): statistical analysis plan by Nathan N. O’Hara, Diane Heels-Ansdell, Sofia Bzovsky, Shannon Dodds, Lehana Thabane, Mohit Bhandari, Gordon Guyatt, P. J. Devereaux, Gerard P. Slobogean, Sheila Sprague, on behalf of the PREP-IT Investigators

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Electronic Versus Traditional Data Collection: A Multicenter Randomized Controlled Perioperative Pain Trial by James S. Khan, Lindsay A. Jibb, Jason W. Busse, Ian Gilron, Stephen Choi, James E. Paul, Michael McGillion, Sean Mackey, D. Norman Buckley, Shun Fu Lee, P. J. Devereaux

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Cost Implications of Left Atrial Appendage Occlusion During Cardiac Surgery: A Cost Analysis of the LAAOS III Trial by Adam Eqbal, Wesley Tong, Andre Lamy, Emilie Belley‐Cote, Domenico Paparella, Alexander Bogachev‐Prokophiev, Alistair G. Royse, Wilko Reents, P. J. Devereaux, Katheryn Brady, Jessica Vincent, Stuart J. Connolly, Richard P. Whitlock

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Assessment of safety and efficacy of mesenchymal stromal cell therapy in preclinical models of acute myocardial infarction: a systematic review protocol by Carly C. Barron, Manoj M. Lalu, Duncan J. Stewart, Dean Fergusson, Homer Yang, David Moher, Peter Liu, David Mazer, P. J. Devereaux, Lauralyn McIntyre, On Behalf of the Canadian Perioperative Anesthesia Clinical Trials Group

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Immune biomarkers predictive of respiratory viral infection in elderly nursing home residents. by Jennie Johnstone, Robin Parsons, Fernando Botelho, Jamie Millar, Shelly McNeil, Tamas Fulop, Janet McElhaney, Melissa K Andrew, Stephen D Walter, P J Devereaux, Mehrnoush Malekesmaeili, Ryan R Brinkman, James Mahony, Jonathan Bramson, Mark Loeb

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MyTEMP: Statistical Analysis Plan of a Registry-Based, Cluster-Randomized Clinical Trial by Stephanie N. Dixon, Jessica M. Sontrop, Ahmed Al-Jaishi, Lauren Killin, Christopher W. McIntyre, Sierra Anderson, Amit Bagga, Derek Benjamin, Peter Blake, P. J. Devereaux, Eduard Iliescu, Arsh Jain, Charmaine E. Lok, Gihad Nesrallah, Matthew J. Oliver, Sanjay Pandeya, Manish M. Sood, Paul Tam, Ron Wald, Michael Walsh, Merrick Zwarenstein, Amit X. Garg

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Use of Anticoagulation Therapy in Patients With Perioperative Atrial Fibrillation After Cardiac Surgery: A Systematic Review and Meta-analysis by Michael Ke Wang, MD, Rachel Heo, BHSc, MD, Pascal Meyre, MD, PhD, Louis Park, Steffen Blum, MD, William F. McIntyre, MD, PhD, Emilie Belley-Côté, MD, PhD, Lauren Birchenough, BHSc, Kiven Vuong, Jeff S. Healey, MD, MSc, P.J. Devereaux, MD, PhD, André Lamy, MD, MHSc, David Conen, MD, MPH

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Association Between Perioperative Atrial Fibrillation and Long-term Risks of Stroke and Death in Noncardiac Surgery: Systematic Review and Meta-analysis by Jessica T. Huynh, MD, Jeff S. Healey, MD, Kevin J. Um, MD, Maria E. Vadakken, Anand S. Rai, BSc, David Conen, MD, Pascal Meyre, MD, Jawad H. Butt, MD, Hooman Kamel, MD, Seleman J. Reza, BSc, Stephanie T. Nguyen, HBSc, Zardasht Oqab, MD, P.J. Devereaux, MD, Kumar Balasubramanian, MSc, Alexander P. Benz, MD, Emilie P. Belley-Cote, MD, William F. McIntyre, MD

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Effect of Colchicine on the Risk of Perioperative Acute Kidney Injury: Clinical Protocol of a Substudy of the Colchicine for the Prevention of Perioperative Atrial Fibrillation Ran... by Amit X. Garg, Meaghan Cuerden, Juan Cata, Matthew T. V. Chan, P. J. Devereaux, Edith Fleischmann, Ascensión Martín Grande, Barbara Kabon, Giovanni Landoni, Donna E. Maziak, Sean McLean MD, Chirag Parikh, Ekaterine Popova, Cara Reimer, Juan Carlos Trujillo Reyes, Pavel Roshanov, Daniel I. Sessler, Sadeesh Srinathan, Jessica M. Sontrop, Anna Gonzalez Tallada, Michael Ke Wang, Jennifer R. Wells, David Conen

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Continuous Noninvasive Remote Automated Blood Pressure Monitoring With Novel Wearable Technology: A Preliminary Validation Study by Michael H McGillion, Nazari Dvirnik, Stephen Yang, Emilie Belley-Côté, Andre Lamy, Richard Whitlock, Maura Marcucci, Flavia K Borges, Emmanuelle Duceppe, Carley Ouellette, Marissa Bird, Sandra L Carroll, David Conen, Jean-Eric Tarride, Prathiba Harsha, Ted Scott, Amber Good, Krysten Gregus, Karla Sanchez, Pamela Benoit, Julian Owen, Valerie Harvey, Elizabeth Peter, Jeremy Petch, Jessica Vincent, Michelle Graham, P J Devereaux

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Safety of Continuing Trastuzumab Despite Mild Cardiotoxicity by Darryl P. Leong, MBBS, MPH, MBiostat, PhD, Tammy Cosman, PhD, Muhammad M. Alhussein, MD, Nidhi Kumar Tyagi, MBChB, Sarah Karampatos, MS, Carly C. Barron, MD, MS, Douglas Wright, MD, Vikas Tandon, MD, Patrick Magloire, MD, Philip Joseph, MD, David Conen, MD, MPH, P.J. Devereaux, MD, PhD, Peter M. Ellis, MBBS, MMed, PhD, Som D. Mukherjee, MD, MS, Sukhbinder Dhesy-Thind, MD, MS

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Major Outcomes With Personalized Dialysate TEMPerature (MyTEMP): Rationale and Design of a Pragmatic, Registry-Based, Cluster Randomized Controlled Trial by Ahmed A. Al-Jaishi, Christopher W. McIntyre, Jessica M. Sontrop, Stephanie N. Dixon, Sierra Anderson, Amit Bagga, Derek Benjamin, David Berry, Peter G. Blake, Laura Chambers, Patricia C. K. Chan, Nicole Delbrouck, P. J. Devereaux, Luis F. Ferreira-Divino, Richard Goluch, Laura Gregor, Jeremy M. Grimshaw, Garth Hanson, Eduard Iliescu, Arsh K. Jain, Charmaine E. Lok, Reem A. Mustafa, Bharat Nathoo, Gihad E. Nesrallah, Matthew J. Oliver, Sanjay Pandeya, Malvinder S. Parmar, David Perkins, Justin Presseau, Eli Rabin, Joanna Sasal, Tanya Shulman, Manish M. Sood, Andrew Steele, Paul Tam, Daniel Tascona, Davinder Wadehra, Ron Wald, Michael Walsh, Paul Watson, Walter Wodchis, Phillip Zager, Merrick Zwarenstein, Amit X. Garg

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Effect of a Perioperative Hypotension-Avoidance Strategy Versus a Hypertension-Avoidance Strategy on the Risk of Acute Kidney Injury: A Clinical Research Protocol for a Substudy of... by Amit X. Garg, Meaghan Cuerden, Hector Aguado, Mohammed Amir, Emilie P. Belley-Cote, Keyur Bhatt, Bruce M. Biccard, Flavia K. Borges, Matthew Chan, David Conen, Emmanuelle Duceppe, Sergey Efremov, John Eikelboom, Edith Fleischmann, Landoni Giovanni, Peter Gross, Raja Jayaram, Mikhail Kirov, Ydo Kleinlugtenbelt, Andrea Kurz, Andre Lamy, Kate Leslie, Valery Likhvantsev, Vladimir Lomivorotov, Maura Marcucci, Maria José Martínez-Zapata, Michael McGillion, William McIntyre, Christian Meyhoff, Sandra Ofori, Thomas Painter, Pilar Paniagua, Chirag Parikh, Joel Parlow, Ameen Patel, Carisi Polanczyk, Toby Richards, Pavel Roshanov, Denis Schmartz, Daniel Sessler, Tim Short, Jessica M. Sontrop, Jessica Spence, Sadeesh Srinathan, David Stillo, Wojciech Szczeklik, Vikas Tandon, David Torres, Thomas Van Helder, Jessica Vincent, C. Y. Wang, Michael Wang, Richard Whitlock, Maria Wittmann, Denis Xavier, P. J. Devereaux

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