Germline mutations but not somatic changes at the MYH locus contribute to the pathogenesis of unselected colorectal cancers. by Halford, SE, Rowan, A, Lipton, L, Sieber, O, Pack, K, Thomas, H, Hodgson, S, Bodmer, W, Tomlinson, I

Genetic basis of variation in adenoma multiplicity in ApcMin/+ Mom1S mice. by Haines, J, Johnson, V, Pack, K, Suraweera, N, Slijepcevic, P, Cabuy, E, Coster, M, Ilyas, M, Wilding, J, Sieber, O, Bodmer, W, Tomlinson, I, Silver, A

The APC variants I1307K and E1317Q are associated with colorectal tumors, but not always with a family history. by Frayling, I, Beck, N, Ilyas, M, Dove-Edwin, I, Goodman, P, Pack, K, Bell, J, Williams, C, Hodgson, S, Thomas, H, Talbot, I, Bodmer, W, Tomlinson, I

The type of somatic mutation at APC in familial adenomatous polyposis is determined by the site of the germline mutation: a new facet to Knudson's 'two-hit' hypothesis. by Lamlum, H, Ilyas, M, Rowan, A, Clark, S, Johnson, V, Bell, J, Frayling, I, Efstathiou, J, Pack, K, Payne, S, Roylance, R, Gorman, P, Sheer, D, Neale, K, Phillips, R, Talbot, I, Bodmer, W, Tomlinson, I