Structural basis for leucine sensing by the Sestrin2-mTORC1 pathway by Saxton, Robert Andrew, Wolfson, Rachel Laura, Chantranupong, Lynne, Wang, Tim, Schwartz, Thomas, Sabatini, David, Knockenhauer, Kevin Edward, Pacold, Michael Edward

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mTORC1 Phosphorylation Sites Encode Their Sensitivity to Starvation and Rapamycin by Kang, Seong A., Cervantes, Christopher L., Lim, Daniel Cham-Chin, Ottina, Kathleen, Lou, Hua Jane, Gray, Nathanael S., Turk, Benjamin E., Pacold, Michael Edward, Yaffe, Michael B, Sabatini, David

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Discovery and optimization of piperazine-1-thiourea-based human phosphoglycerate dehydrogenase inhibitors by Rohde, Jason M., Brimacombe, Kyle R., Liu, Li, Pacold, Michael Edward, Yasgar, Adam, Cheff, Dorian M., Lee, Tobie D., Rai, Ganesha, Baljinnyam, Bolormaa, Li, Zhuyin, Simeonov, Anton, Hall, Matthew D., Shen, Min, Sabatini, David, Boxer, Matthew B.

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Dihydropyrimidine Accumulation Is Required for the Epithelial-Mesenchymal Transition by Freinkman, Elizaveta, Comb, William C., Cantor, Jason R., Tam, Wai Leong, Thiru, Prathapan, Kanarek, Naama, Bierie, Brian, Shaul, Yoav, Kim, Dohoon, Chen, Walter W., Possemato, Richard, Reinhardt, Ferenc, Weinberg, Robert A, Yaffe, Michael B, Sabatini, David, Pacold, Michael Edward

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PIK3CA mutant tumors depend on oxoglutarate dehydrogenase by Ilic, Nina, Birsoy, Kıvanç, Aguirre, Andrew J., Singh, Shambhavi, Moody, Susan E., DeAngelo, Joseph D., Spardy, Nicole A., Freinkman, Elizaveta, Weir, Barbara A., Tsherniak, Aviad, Cowley, Glenn S., Root, David E., Asara, John M., Vazquez, Francisca, Widlund, Hans R., Hahn, William C., Kory, Nora, Sabatini, David, Pacold, Michael Edward

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SHMT2 drives glioma cell survival in ischaemia but imposes a dependence on glycine clearance by Kami, Kenjiro, Shelton, Laura M., Ramkissoon, Shakti H., Ligon, Keith L., Snuderl, Matija, Kim, Dohoon, Fiske, Brian Prescott, Birsoy, Kivanc, Freinkman, Elizaveta, Possemato, Richard, Chudnovsky, Yakov, Chen, Walter W., Cantor, Jason R., Gui, Dan Yi, Kwon, ManJae, Kang, Seong Woo, Vander Heiden, Matthew G., Sabatini, David, Pacold, Michael Edward

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A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate by Chan, Sze Ham, Lewis, Caroline, Swier, Lotteke J. Y. M., Chen, Walter W., Sullivan, Lucas Bryan, Fiske, Brian Prescott, Cho, Sung Won, Abu-Remaileh, Monther, Liu, Chieh Ming Jamin, Zhou, Minerva H., Koh, Min Jung, Chung, Haeyoon, Davidson, Shawn M, Luengo, Alba, Vander Heiden, Matthew G., Sabatini, David, Pacold, Michael Edward

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Functional genomics reveals serine synthesis is essential in PHGDH-amplified breast cancer by Possemato, Richard, Marks, Kevin M., Kim, Dohoon, Birsoy, Kivanc, Sethumadhavan, Shalini, Woo, Hin-Koon, Jang, Hyun G., Jha, Abhishek K., Chen, Walter W., Barrett, Francesca G., Stransky, Nicolas, Tsun, Zhi-Yang, Cowley, Glenn S., Barretina, Jordi, Kalaany, Nada Y., Hsu, Peggy P., Ottina, Kathleen, Chan, Albert M., Yuan, Bingbing B., Garraway, Levi A., Root, David E., Mino-Kenudson, Mari, Brachtel, Elena F., Driggers, Edward M., Shaul, Yoav, Pacold, Michael Edward, Sabatini, David

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