PRKCA and multiple sclerosis: Association in independent populations by Saarela, J, Kallio, S, Chen, D, Montpetit, A, Lincoln, MR, Palotie, A, Ebers, G, Hudson, T, Peltonen, L

PRKCA and multiple sclerosis: association in two independent populations by Saarela, J, Kallio, S, Chen, D, Montpetit, A, Jokiaho, A, Choi, E, Asselta, R, Bronnikov, D, Lincoln, MR, Sadovnick, A, Tienari, P, Koivisto, K, Palotie, A, Ebers, G, Hudson, T, Peltonen, L

Distinct variants at LIN28B influence growth in height from birth to adulthood. by Widén, E, Ripatti, S, Cousminer, D, Surakka, I, Lappalainen, T, Järvelin, MR, Eriksson, J, Raitakari, O, Salomaa, V, Sovio, U, Hartikainen, A, Pouta, A, McCarthy, M, Osmond, C, Kajantie, E, Lehtimäki, T, Viikari, J, Kähönen, M, Tyler-Smith, C, Freimer, N, Hirschhorn, J, Peltonen, L, Palotie, A

IFITM3 restricts the morbidity and mortality associated with influenza by Everitt, A, Clare, S, Pertel, T, John, S, Wash, R, Smith, SE, Chin, C, Feeley, E, Sims, J, Adams, D, Wise, H, Kane, L, Goulding, D, Digard, P, Anttila, V, Baillie, J, Walsh, T, Hume, D, Palotie, A, Xue, Y, Colonna, V, Tyler-Smith, C, Dunning, J, Gordon, S, Everingham, K

A quality assessment survey of SNP genotyping laboratories. by Lahermo, P, Liljedahl, U, Alnaes, G, Axelsson, T, Brookes, A, Ellonen, P, Groop, P, Halldén, C, Holmberg, D, Holmberg, K, Keinänen, M, Kepp, K, Kere, J, Kiviluoma, P, Kristensen, V, Lindgren, C, Odeberg, J, Osterman, P, Parkkonen, M, Saarela, J, Sterner, M, Strömqvist, L, Talas, U, Wessman, M, Palotie, A

Proteomic aging clock predicts mortality and risk of common age-related diseases in diverse populations by Argentieri, MA, Xiao, S, Bennett, D, Winchester, L, Nevado-Holgado, AJ, Ghose, U, Albukhari, A, Yao, P, Mazidi, M, Lv, J, Millwood, I, Fry, H, Rodosthenous, RS, Partanen, J, Zheng, Z, Kurki, M, Daly, MJ, Palotie, A, Adams, CJ, Li, L, Clarke, R, Amin, N, Chen, Z, van Duijn, CM

Phenotypic consequences of a genetic predisposition to enhanced nitric oxide signaling by Emdin, C, Khera, A, Klarin, D, Natarajan, P, Zekavat, S, Nomura, A, Haas, M, Aragam, K, Ardissino, D, Wilson, J, Schunkert, H, McPherson, R, Watkins, H, Elosua, R, Bown, M, Samani, N, Baber, U, Erdmann, J, Gormley, P, Palotie, A, Stitziel, N, Gupta, N, Danesh, J, Saleheen, D, Gabriel, S, Kathiresan, S

Toward a roadmap in global biobanking for health by Harris, JR, Burton, P, Knoppers, B, Lindpaintner, K, Bledsoe, M, Brookes, A, Budin-Ljosne, I, Chisholm, R, Cox, D, Deschênes, M, Fortier, I, Hainaut, P, Hewitt, R, Kaye, J, Litton, J, Metspalu, A, Ollier, B, Palmer, L, Palotie, A, Pasterk, M, Perola, M, Riegman, P, Van Ommen, G, Yuille, M, Zatloukal, K

Toward a roadmap in global biobanking for health. by Harris, JR, Burton, P, Knoppers, B, Lindpaintner, K, Bledsoe, M, Brookes, A, Budin-Ljøsne, I, Chisholm, R, Cox, D, Deschênes, M, Fortier, I, Hainaut, P, Hewitt, R, Kaye, J, Litton, J, Metspalu, A, Ollier, B, Palmer, L, Palotie, A, Pasterk, M, Perola, M, Riegman, P, van Ommen, G, Yuille, M, Zatloukal, K

Phenome-wide association studies across large population cohorts support drug target validation by Diogo, D, Tian, C, Franklin, C, Alanne-Kinnunen, M, March, M, Spencer, C, Vangjeli, C, Weale, M, Mattsson, H, Kilpeläinen, E, Sleiman, P, Reilly, D, McElwee, J, Maranville, J, Chatterjee, A, Bhandari, A, Nguyen, K, Estrada, K, Reeve, M, Hutz, J, Bing, N, John, S, Macarthur, D, Salomaa, V, Ripatti, S, Hakonarson, H, Daly, M, Palotie, A, Hinds, D, Donnelly, P, Fox, C, Day-Williams, A, Plenge, R, Runz, H

Pro-inflammatory fatty acid profile and colorectal cancer risk: A Mendelian randomisation analysis by May-Wilson, S, Sud, A, Law, PJ, Palin, K, Tuupanen, S, Gylfe, A, Hänninen, UA, Cajuso, T, Tanskanen, T, Kondelin, J, Kaasinen, E, Sarin, AP, Eriksson, JG, Rissanen, H, Knekt, P, Pukkala, E, Jousilahti, P, Salomaa, V, Ripatti, S, Palotie, A, Renkonen-Sinisalo, L, Lepistö, A, Böhm, J, Mecklin, JP, Al-Tassan, NA, Palles, C, Farrington, SM, Timofeeva, MN, Meyer, BF, Wakil, SM, Campbell, H, Smith, CG, Idziaszczyk, S, Maughan, TS, Fisher, D, Kerr, R, Kerr, D, Passarelli, MN, Figueiredo, JC, Buchanan, DD, Win, AK, Hopper, JL, Jenkins, MA, Lindor, NM, Newcomb, PA, Gallinger, S, Conti, D, Schumacher, F, Casey, G, Aaltonen, LA, Cheadle, JP, Tomlinson, IP, Dunlop, MG, Houlston, RS

Distribution and medical impact of loss-of-function variants in the Finnish founder population by Lim, E, Würtz, P, Havulinna, A, Palta, P, Tukiainen, T, Rehnström, K, Esko, T, Mägi, R, Inouye, M, Lappalainen, T, Chan, Y, Salem, R, Lek, M, Flannick, J, Sim, X, Manning, A, Ladenvall, C, Bumpstead, S, Hämäläinen, E, Aalto, K, Maksimow, M, Salmi, M, Blankenberg, S, Ardissino, D, Shah, S, Horne, B, McPherson, R, Hovingh, G, Reilly, M, Watkins, H, Goel, A, Farrall, M, Girelli, D, Reiner, A, Stitziel, N, Kathiresan, S, Gabriel, S, Barrett, J, Lehtimäki, T, Laakso, M, Groop, L, Kaprio, J, Perola, M, McCarthy, M, Boehnke, M, Altshuler, D, Lindgren, C, Hirschhorn, J, Metspalu, A, Freimer, N, Zeller, T, Jalkanen, S, Koskinen, S, Raitakari, O, Durbin, R, Macarthur, D, Salomaa, V, Ripatti, S, Daly, M, Palotie, A

Mendelian randomisation analysis strongly implicates adiposity with risk of developing colorectal cancer by Jarvis, D, Mitchell, J, Law, P, Palin, K, Tuupanen, S, Gylfe, A, Hänninen, U, Cajuso, T, Tanskanen, T, Kondelin, J, Kaasinen, E, Sarin, A, Kaprio, J, Eriksson, J, Rissanen, H, Knekt, P, Pukkala, E, Jousilahti, P, Salomaa, V, Ripatti, S, Palotie, A, Järvinen, H, Renkonen-Sinisalo, L, Lepistö, A, Böhm, J, Meklin, J, Al-Tassan, N, Palles, C, Martin, L, Barclay, E, Farrington, S, Timofeeva, M, Meyer, B, Wakil, S, Campbell, H, Smith, C, Idziaszczyk, S, Maughan, T, Kaplan, R, Kerr, R, Kerr, D, Buchanan, D, Win, A, Hopper, J, Jenkins, M, Lindor, M, Newcomb, P, Gallinger, S, Conti, D, Schumacher, F, Casey, G, Taipale, J, Aaltonen, L, Cheadle, J, Dunlop, M, Tomlinson, I, Houlston, R

Genome-wide association study and meta-analysis in Northern European populations replicate multiple colorectal cancer risk loci by Tanskanen, T, van den Berg, L, Välimäki, N, Aavikko, M, Ness-Jensen, E, Hveem, K, Wettergren, Y, Lindskog, E, Tõnisson, N, Metspalu, A, Silander, K, Orlando, G, Law, PJ, Tuupanen, S, Gylfe, AE, Hänninen, UA, Cajuso, T, Kondelin, J, Sarin, AP, Pukkala, E, Jousilahti, P, Salomaa, V, Ripatti, S, Palotie, A, Järvinen, H, Renkonen-Sinisalo, L, Lepistö, A, Böhm, J, Mecklin, JP, Al-Tassan, NA, Palles, C, Martin, L, Barclay, E, Tenesa, A, Farrington, SM, Timofeeva, MN, Meyer, BF, Wakil, SM, Campbell, H, Smith, CG, Idziaszczyk, S, Maughan, TS, Kaplan, R, Kerr, R, Kerr, D, Buchanan, DD, Win, AK, Hopper, J, Jenkins, MA, Newcomb, PA, Gallinger, S, Conti, D, Schumacher, FR, Casey, G, Cheadle, JP, Dunlop, MG, Tomlinson, IP, Houlston, RS, Palin, K, Aaltonen, LA

A central role for GRB10 in regulation of islet function in man by Prokopenko, I, Poon, W, Mägi, R, Prasad B, R, Salehi, SA, Almgren, P, Osmark, P, Bouatia-Naji, N, Wierup, N, Fall, T, Stančáková, A, Barker, A, Lagou, V, Osmond, C, Xie, W, Lahti, J, Jackson, A, Cheng, Y, Liu, J, O'Connell, JR, Blomstedt, P, Fadista, J, Alkayyali, S, Dayeh, T, Ahlqvist, E, Taneera, J, Lecoeur, C, Kumar, A, Hansson, O, Hansson, K, Voight, B, Kang, H, Levy-Marchal, C, Vatin, V, Palotie, A, Syvänen, A, Mari, A, Weedon, M, Loos, R, Ong, K, Nilsson, P, Isomaa, B, Tuomi, T, Wareham, N, Stumvoll, M, Widen, E, Lakka, T, Langenberg, C, Tönjes, A, Rauramaa, R, Kuusisto, J, Frayling, T, Froguel, P, Walker, M, Eriksson, J, Ling, C, Kovacs, P, Ingelsson, E, McCarthy, M, Shuldiner, A, Silver, K, Laakso, M, Groop, L, Lyssenko, V

Analysis of protein-coding genetic variation in 60,706 humans. by Lek, M, Karczewski, K, Minikel, E, Samocha, K, Banks, E, Fennell, T, O'Donnell-Luria, A, Ware, J, Hill, A, Cummings, B, Tukiainen, T, Birnbaum, D, Kosmicki, J, Duncan, L, Estrada, K, Zhao, F, Zou, J, Pierce-Hoffman, E, Berghout, J, Cooper, D, Deflaux, N, DePristo, M, Do, R, Flannick, J, Fromer, M, Gauthier, L, Goldstein, J, Gupta, N, Howrigan, D, Kiezun, A, Kurki, M, Moonshine, A, Natarajan, P, Orozco, L, Peloso, G, Poplin, R, Rivas, M, Ruano-Rubio, V, Rose, S, Ruderfer, D, Shakir, K, Stenson, P, Stevens, C, Thomas, B, Tiao, G, Tusie-Luna, M, Weisburd, B, Won, H, Yu, D, Altshuler, D, Ardissino, D, Boehnke, M, Danesh, J, Donnelly, S, Elosua, R, Florez, J, Gabriel, S, Getz, G, Glatt, S, Hultman, C, Kathiresan, S, Laakso, M, McCarroll, S, McCarthy, M, McGovern, D, McPherson, R, Neale, B, Palotie, A, Purcell, S, Saleheen, D, Scharf, J, Sklar, P, Sullivan, P, Tuomilehto, J, Tsuang, M, Watkins, H, Wilson, J, Daly, M, MacArthur, D

A genome-wide screen for interactions reveals a new locus on 4p15 modifying the effect of waist-to-hip ratio on total cholesterol. by Surakka, I, Isaacs, A, Karssen, L, Laurila, P, Middelberg, R, Tikkanen, E, Ried, J, Lamina, C, Mangino, M, Igl, W, Hottenga, J, Lagou, V, van der Harst, P, Mateo Leach, I, Esko, T, Kutalik, Z, Wainwright, N, Struchalin, M, Sarin, A, Kangas, A, Viikari, J, Perola, M, Rantanen, T, Petersen, A, Soininen, P, Johansson, A, Soranzo, N, Heath, A, Papamarkou, T, Prokopenko, I, Tönjes, A, Kronenberg, F, Döring, A, Rivadeneira, F, Montgomery, G, Whitfield, J, Kähönen, M, Lehtimäki, T, Freimer, N, Willemsen, G, de Geus, E, Palotie, A, Sandhu, MS, Waterworth, D, Metspalu, A, Stumvoll, M, Uitterlinden, A, Jula, A, Navis, G, Wijmenga, C, Wolffenbuttel, B, Taskinen, MR, Ala-Korpela, M, Kaprio, J, Kyvik, K, Boomsma, D, Pedersen, N, Gyllensten, U, Wilson, J, Rudan, I, Campbell, H, Pramstaller, P, Spector, T, Witteman, J, Eriksson, J, Salomaa, V, Oostra, B, Raitakari, O, Wichmann, H, Gieger, C, Järvelin, MR, Martin, N, Hofman, A, McCarthy, M, Peltonen, L, van Duijn, C, Aulchenko, Y, Ripatti, S

A genome-wide association meta-analysis identifies new childhood obesity loci by Bradfield, J, Taal, H, Timpson, N, Scherag, A, Lecoeur, C, Warrington, N, Hypponen, E, Holst, C, Valcarcel, B, Thiering, E, Salem, R, Schumacher, F, Cousminer, D, Sleiman, P, Zhao, J, Berkowitz, R, Vimaleswaran, K, Jarick, I, Pennell, C, Evans, D, St Pourcain, B, Berry, D, Mook-Kanamori, DO, Hofman, A, Rivadeneira, F, Uitterlinden, A, van Duijn, C, van der Valk, R, de Jongste, J, Postma, D, Boomsma, D, Gauderman, W, Hassanein, M, Lindgren, C, Mägi, R, Boreham, C, Neville, C, Moreno, L, Elliott, P, Pouta, A, Hartikainen, A, Li, M, Raitakari, O, Lehtimäki, T, Eriksson, J, Palotie, A, Dallongeville, J, Das, S, Deloukas, P, McMahon, G, Ring, S, Kemp, J, Buxton, J, Blakemore, A, Bustamante, M, Guxens, M, Hirschhorn, J, Gillman, M, Kreiner-Møller, E, Bisgaard, H, Gilliland, F, Heinrich, J, Wheeler, E, Barroso, I, O'Rahilly, S, Meirhaeghe, A, Sørensen, T, Power, C, Palmer, L, Hinney, A, Widen, E, Farooqi, I, McCarthy, M, Froguel, P, Meyre, D, Hebebrand, J, Jarvelin, MR, Jaddoe, V, Smith, G, Hakonarson, H, Grant, S

Common variants at 12q15 and 12q24 are associated with infant head circumference. by Taal, H, St Pourcain, B, Thiering, E, Das, S, Mook-Kanamori, DO, Warrington, N, Kaakinen, M, Kreiner-Møller, E, Bradfield, J, Freathy, R, Geller, F, Guxens, M, Cousminer, D, Kerkhof, M, Timpson, N, Ikram, M, Beilin, L, Bønnelykke, K, Buxton, J, Charoen, P, Chawes, B, Eriksson, J, Evans, D, Hofman, A, Kemp, J, Kim, C, Klopp, N, Lahti, J, Lye, S, McMahon, G, Mentch, F, Müller-Nurasyid, M, O'Reilly, P, Prokopenko, I, Rivadeneira, F, Steegers, E, Sunyer, J, Tiesler, C, Yaghootkar, H, Breteler, M, Decarli, C, Breteler, M, Debette, S, Fornage, M, Gudnason, V, Launer, L, van der Lugt, A, Mosley, T, Seshadri, S, Smith, A, Vernooij, M, Blakemore, A, Chiavacci, R, Feenstra, B, Fernandez-Banet, J, Grant, S, Hartikainen, A, van der Heijden, A, Iñiguez, C, Lathrop, M, McArdle, W, Mølgaard, A, Newnham, J, Palmer, L, Palotie, A, Pouta, A, Ring, S, Sovio, U, Standl, M, Uitterlinden, A, Wichmann, H, Vissing, N, DeCarli, C, van Duijn, C, McCarthy, M, Koppelman, G, Estivill, X, Hattersley, A, Melbye, M, Bisgaard, H, Pennell, C, Widen, E, Hakonarson, H, Smith, G, Heinrich, J, Jarvelin, MR, Jaddoe, V

Integrating common and rare genetic variation in diverse human populations. by Altshuler, D, Gibbs, R, Peltonen, L, Altshuler, D, Gibbs, R, Peltonen, L, Dermitzakis, E, Schaffner, S, Yu, F, Peltonen, L, Dermitzakis, E, Bonnen, P, Altshuler, D, Gibbs, R, de Bakker, P, Deloukas, P, Gabriel, S, Gwilliam, R, Hunt, S, Inouye, M, Jia, X, Palotie, A, Parkin, M, Whittaker, P, Yu, F, Chang, K, Hawes, A, Lewis, L, Ren, Y, Wheeler, D, Gibbs, R, Muzny, D, Barnes, C, Darvishi, K, Hurles, M, Korn, J, Kristiansson, K, Lee, C, McCarrol, SA, Nemesh, J, Dermitzakis, E, Keinan, A, Montgomery, S, Pollack, S, Price, A, Soranzo, N, Bonnen, P, Gibbs, R, Gonzaga-Jauregui, C, Keinan, A, Price, A, Yu, F, Anttila, V, Brodeur, W, Daly, M, Leslie, S, McVean, G, Moutsianas, L, Nguyen, H, Schaffner, S, Zhang, Q, Ghori, M, McGinnis, R, McLaren, W, Pollack, S, Price, A, Schaffner, S, Takeuchi, F, Grossman, SR, Shlyakhter, I, Hostetter, E, Sabeti, P, Adebamowo, C, Foster, M, Gordon, DR, Licinio, J, Manca, M, Marshall, P, Matsuda, I, Ngare, D, Wang, V, Reddy, D, Rotimi, C, Royal, C, Sharp, R, Zeng, C, Brooks, L, McEwen, J