An Observatory for the <i>MET</i> Oncogene: A Guide for Targeted Therapies by Dogus M. Altintas, Paolo M. Comoglio

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MET Activation and Physical Dynamics of the Metastatic Process: The Paradigm of Cancers of Unknown Primary Origin by Giulia M. Stella, Silvia Benvenuti, Alessandra Gentile, Paolo M. Comoglio

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A receptor-antibody hybrid hampering MET-driven metastatic spread by Chiara Modica, Cristina Basilico, Cristina Chiriaco, Nicla Borrelli, Paolo M. Comoglio, Elisa Vigna

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hOA-DN30: a highly effective humanized single-arm MET antibody inducing remission of ‘MET-addicted’ cancers by Ilaria Martinelli, Chiara Modica, Cristina Chiriaco, Cristina Basilico, James M. Hughes, Simona Corso, Silvia Giordano, Paolo M. Comoglio, Elisa Vigna

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Correction: hOA-DN30: a highly effective humanized single-arm MET antibody inducing remission of ‘MET-addicted’ cancers by Ilaria Martinelli, Chiara Modica, Cristina Chiriaco, Cristina Basilico, James M. Hughes, Simona Corso, Silvia Giordano, Paolo M. Comoglio, Elisa Vigna

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Cancer of Unknown Primary (CUP): genetic evidence for a novel nosological entity? A case report by Silvia Benvenuti, Melissa Milan, Elena Geuna, Alberto Pisacane, Rebecca Senetta, Gennaro Gambardella, Giulia M Stella, Filippo Montemurro, Anna Sapino, Carla Boccaccio, Paolo M Comoglio

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MET Exon 14 Skipping: A Case Study for the Detection of Genetic Variants in Cancer Driver Genes by Deep Learning by Vladimir Nosi, Alessandrì Luca, Melissa Milan, Maddalena Arigoni, Silvia Benvenuti, Davide Cacchiarelli, Marcella Cesana, Sara Riccardo, Lucio Di Filippo, Francesca Cordero, Marco Beccuti, Paolo M. Comoglio, Raffaele A. Calogero

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MicroRNA 483‐3p overexpression unleashes invasive growth of metastatic colorectal cancer via NDRG1 downregulation and ensuing activation of the ERBB3/AKT axis by Ermes Candiello, Gigliola Reato, Federica Verginelli, Gennaro Gambardella, Antonio D′Ambrosio, Noemi Calandra, Francesca Orzan, Antonella Iuliano, Raffaella Albano, Francesco Sassi, Paolo Luraghi, Paolo M. Comoglio, Andrea Bertotti, Livio Trusolino, Carla Boccaccio

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Mutated axon guidance gene PLXNB2 sustains growth and invasiveness of stem cells isolated from cancers of unknown primary by Serena Brundu, Virginia Napolitano, Giulia Franzolin, Ettore Lo Cascio, Roberta Mastrantonio, Gabriele Sardo, Eliano Cascardi, Federica Verginelli, Sergio Sarnataro, Gennaro Gambardella, Alberto Pisacane, Alessandro Arcovito, Carla Boccaccio, Paolo M Comoglio, Enrico Giraudo, Luca Tamagnone

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Magic-factor 1, a partial agonist of Met, induces muscle hypertrophy by protecting myogenic progenitors from apoptosis. by Marco Cassano, Stefano Biressi, Amanda Finan, Laura Benedetti, Claudia Omes, Renata Boratto, Frank Martin, Marcello Allegretti, Vania Broccoli, Gabriella Cusella De Angelis, Paolo M Comoglio, Cristina Basilico, Yvan Torrente, Paolo Michieli, Giulio Cossu, Maurilio Sampaolesi

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Cancer of unknown primary stem-like cells model multi-organ metastasis and unveil liability to MEK inhibition by Federica Verginelli, Alberto Pisacane, Gennaro Gambardella, Antonio D’Ambrosio, Ermes Candiello, Marco Ferrio, Mara Panero, Laura Casorzo, Silvia Benvenuti, Eliano Cascardi, Rebecca Senetta, Elena Geuna, Andrea Ballabio, Filippo Montemurro, Anna Sapino, Paolo M. Comoglio, Carla Boccaccio

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ERBB3 overexpression due to miR-205 inactivation confers sensitivity to FGF, metabolic activation, and liability to ERBB3 targeting in glioblastoma by Francesca De Bacco, Francesca Orzan, Jessica Erriquez, Elena Casanova, Ludovic Barault, Raffaella Albano, Antonio D’Ambrosio, Viola Bigatto, Gigliola Reato, Monica Patanè, Bianca Pollo, Geoffrey Kuesters, Carmine Dell’Aglio, Laura Casorzo, Serena Pellegatta, Gaetano Finocchiaro, Paolo M. Comoglio, Carla Boccaccio

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Coexisting cancer stem cells with heterogeneous gene amplifications, transcriptional profiles, and malignancy are isolated from single glioblastomas by Francesca De Bacco, Francesca Orzan, Giovanni Crisafulli, Marta Prelli, Claudio Isella, Elena Casanova, Raffaella Albano, Gigliola Reato, Jessica Erriquez, Antonio D’Ambrosio, Mara Panero, Carmine Dall’Aglio, Laura Casorzo, Manuela Cominelli, Francesca Pagani, Antonio Melcarne, Pietro Zeppa, Roberto Altieri, Isabella Morra, Paola Cassoni, Diego Garbossa, Anna Cassisa, Alice Bartolini, Serena Pellegatta, Paolo M. Comoglio, Gaetano Finocchiaro, Pietro L. Poliani, Carla Boccaccio

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