Hepatic Surgical Stress Promotes Systemic Immunothrombosis That Results in Distant Organ Injury by Hongji Zhang, Hongji Zhang, Julie Goswami, Patrick Varley, Dirk J. van der Windt, Jinghua Ren, Jinghua Ren, Patricia Loughran, Patricia Loughran, Hamza Yazdani, Matthew D. Neal, Richard L. Simmons, Jinxiang Zhang, Allan Tsung, Hai Huang

Get full text

Interferon Regulatory Factor-1 (IRF1) activates autophagy to promote liver ischemia/reperfusion injury by inhibiting β-catenin in mice. by Bing Yan, Jing Luo, Christof Kaltenmeier, Qiang Du, Donna B Stolz, Patricia Loughran, Yihe Yan, Xiao Cui, David A Geller

Get full text

ZLN005, a PGC-1α Activator, Protects the Liver against Ischemia–Reperfusion Injury and the Progression of Hepatic Metastases by Celine Tohme, Tony Haykal, Ruiqi Yang, Taylor J. Austin, Patricia Loughran, David A. Geller, Richard L. Simmons, Samer Tohme, Hamza O. Yazdani

Get full text

Augmenting autophagy to treat acute kidney injury during endotoxemia in mice. by Gina M Howell, Hernando Gomez, Richard D Collage, Patricia Loughran, Xianghong Zhang, Daniel A Escobar, Timothy R Billiar, Brian S Zuckerbraun, Matthew R Rosengart

Get full text

Signaling of High Mobility Group Box 1 (HMGB1) through Toll-like Receptor 4 in Macrophages Requires CD14 by Sodam Kim, Sun Young Kim, John P. Pribis, Michael Lotze, Kevin P. Mollen, Richard Shapiro, Patricia Loughran, Melanie J. Scott, Timothy R. Billiar

Get full text

Hepatocytes Are Resistant to Cell Death From Canonical and Non-Canonical Inflammasome-Activated PyroptosisSummary by Ping Sun, Jie Zhong, Hong Liao, Patricia Loughran, Joud Mulla, Guang Fu, Da Tang, Jie Fan, Timothy R. Billiar, Wentao Gao, Melanie J. Scott

Get full text

Caspase1/11 signaling affects muscle regeneration and recovery following ischemia, and can be modulated by chloroquine by Ulka Sachdev, Ricardo Ferrari, Xiangdong Cui, Abish Pius, Amrita Sahu, Michael Reynolds, Hong Liao, Ping Sun, Sunita Shinde, Fabrisia Ambrosio, Sruti Shiva, Patricia Loughran, Melanie Scott

Get full text

Inhaled Carbon Monoxide Protects against the Development of Shock and Mitochondrial Injury following Hemorrhage and Resuscitation. by Hernando Gomez, Benjamin Kautza, Daniel Escobar, Ibrahim Nassour, Jason Luciano, Ana Maria Botero, Lisa Gordon, Silvia Martinez, Andre Holder, Olufunmilayo Ogundele, Patricia Loughran, Matthew R Rosengart, Michael Pinsky, Sruti Shiva, Brian S Zuckerbraun

Get full text

Inflammatory Caspase Activity Mediates HMGB1 Release and Differentiation in Myoblasts Affected by Peripheral Arterial Disease by Ricardo Ferrari, Bowen Xie, Edwyn Assaf, Kristin Morder, Melanie Scott, Hong Liao, Michael J. Calderon, Mark Ross, Patricia Loughran, Simon C. Watkins, Iraklis Pipinos, George Casale, Edith Tzeng, Ryan McEnaney, Ulka Sachdev

Get full text

Enhanced Neutrophil Extracellular Trap Formation in Acute Pancreatitis Contributes to Disease Severity and Is Reduced by Chloroquine by Pranav Murthy, Aatur D. Singhi, Mark A. Ross, Patricia Loughran, Pedram Paragomi, Georgios I. Papachristou, David C. Whitcomb, Amer H. Zureikat, Michael T. Lotze, Herbert J. Zeh III, Herbert J. Zeh III, Brian A. Boone, Brian A. Boone

Get full text

Encouraging long‐term survival following autophagy inhibition using neoadjuvant hydroxychloroquine and gemcitabine for high‐risk patients with resectable pancreatic carcinoma by Samer S. AlMasri, Mazen S. Zenati, Annissa Desilva, Ibrahim Nassour, Brian A. Boone, Aatur D. Singhi, David L. Bartlett, Lance A. Liotta, Virginia Espina, Patricia Loughran, Michael T. Lotze, Alessandro Paniccia, Herbert J. Zeh III, Amer H. Zureikat, Nathan Bahary

Get full text

A road map from single-cell transcriptome to patient classification for the immune response to trauma by Tianmeng Chen, Matthew J. Delano, Kong Chen, Jason L. Sperry, Rami A. Namas, Ashley J. Lamparello, Meihong Deng, Julia Conroy, Lyle L. Moldawer, Philip A. Efron, Patricia Loughran, Christopher Seymour, Derek C. Angus, Yoram Vodovotz, Wei Chen, Timothy R. Billiar

Get full text