1201-A An antibody-drug conjugate selectively targeting a GSTA glycosite-signature neoantigen epitope of MUC1 in cancer cells with COSMC deficiency by Hua Zhu, Yu He, Patrick Hwu, Yue Ma, Dapeng Zhou

Successful management of pre-existing psoriatic arthritis through targeting the IL-23/IL-17 axis in cancer patients receiving immune checkpoint inhibitor therapy: a case series by Pavlos Msaouel, Adi Diab, Patrick Hwu, Sang T. Kim, Matthew Campbell, Yuanteng Jeff Li

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Celebrating a decade of the Journal for ImmunoTherapy of Cancer by James L Gulley, Pedro J Romero, Patrick Hwu, Mary Dean, Samuel Million-Weaver

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229 CX3CR1 in exhausted CD8 T cell states by Patrick Hwu, Apoorvi Chaudhri, Gregory Lizee, Yunfei Wang, Shao-Hsi Hung, Ulrich Von Andrian, Gordon Freeman

Strategies for improving the management of immune-related adverse events by James L Gulley, Patrick Hwu, Gennaro Ciliberto, Aung Naing, Funda Meric-Bernstam, Michael B Atkins, Joud Hajjar

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Tumor-infiltrating mast cells confer resistance to immunotherapy in pancreatic cancer by Ying Ma, Xiangqin Zhao, Jingyan Feng, Suimin Qiu, Baoan Ji, Lu Huang, Patrick Hwu, Craig D. Logsdon, Huamin Wang

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Rethinking the immunotherapy numbers game by Shari Pilon-Thomas, Patrick Hwu, Rebecca A Bekker, Mohammad U Zahid, Jennifer M Binning, Bryan Q Spring, Heiko Enderling

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T-cell lymphoma secondary to checkpoint inhibitor therapy by Patrick Hwu, Kartik Anand, Joe Ensor, Sai Ravi Pingali, Madeleine Duvic, Stephen Chiang, Roberto Miranda, Youli Zu, Swaminathan Iyer

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Cervical Cancer Neoantigen Landscape and Immune Activity is Associated with Human Papillomavirus Master Regulators by Yong Qin, Suhendan Ekmekcioglu, Marie-Andrée Forget, Lorant Szekvolgyi, Patrick Hwu, Elizabeth A. Grimm, Amir A. Jazaeri, Jason Roszik, Jason Roszik

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Co-stimulation through 4-1BB/CD137 improves the expansion and function of CD8(+) melanoma tumor-infiltrating lymphocytes for adoptive T-cell therapy. by Jessica Ann Chacon, Richard C Wu, Pariya Sukhumalchandra, Jeffrey J Molldrem, Amod Sarnaik, Shari Pilon-Thomas, Jeffrey Weber, Patrick Hwu, Laszlo Radvanyi

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808 The CX3CL1-CX3CR1 chemokine axis can contribute to tumor immune evasion and blockade with a novel CX3CR1 monoclonal antibody enhances responses to anti-PD-1 immunotherapy by Patrick Hwu, Apoorvi Chaudhri, Ping Hua, Xia Bu, Michael A Davies, Yunfei Wang, Shao-Hsi Hung, Ulrich Von Andrian, Gordon Freeman, Gregory A Lizee

A case report of Grover’s disease from immunotherapy-a skin toxicity induced by inhibition of CTLA-4 but not PD-1 by Patrick Hwu, Cara Haymaker, Chantale Bernatchez, Marc Uemura, Adi Diab, Natalie McQuail, Elizabeth Sirmans, Faisal Faˈak, Courtney W. Hudgens, Lydia Barbara, Jonathan L. Curry, Michael T. Tetzlaff

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The “Great Debate” at Immunotherapy Bridge 2021, December 1st–2nd, 2021 by Paolo A. Ascierto, Lisa H. Butterfield, Olivera J. Finn, Andrew Futreal, Omid Hamid, Theresa LaVallee, Michael A. Postow, Igor Puzanov, Jeffrey Sosman, Bernard A. Fox, Patrick Hwu

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187 Multi-omic single-cell profiling demonstrates that competition for fatty acids and fatty acid oxidation enables tumor-infiltrating lymphocyte function and survival by Navin Varadarajan, Patrick Hwu, Cara Haymaker, Chantale Bernatchez, Caitlin Creasy, Scott Woodman, Jay R Adolacion, Michal Harel, Xingyue An, Melisa Angela Paniagua, Mohsen Fathi, Ali Rezvan, Tamar Geiger, Jonathan Robinson, Amit Amritkar

Challenges and opportunities in cancer immunotherapy: a Society for Immunotherapy of Cancer (SITC) strategic vision by James L Gulley, Deborah Collyar, Pedro J Romero, Christian M Capitini, Leisha A Emens, Avery D Posey, Patrick Hwu, Jennifer A Wargo, Ann W Silk, Ana Carrizosa Anderson, Tullia C Bruno

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Long-term overall survival and prognostic score predicting survival: the IMPACT study in precision medicine by Apostolia-Maria Tsimberidou, David S. Hong, Jennifer J. Wheler, Gerald S. Falchook, Filip Janku, Aung Naing, Siqing Fu, Sarina Piha-Paul, Carrie Cartwright, Russell R. Broaddus, Graciela M. Nogueras Gonzalez, Patrick Hwu, Razelle Kurzrock

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High-Throughput Screening of Myxoid Liposarcoma Cell Lines: Survivin Is Essential for Tumor Growth by Marieke A. de Graaff, Shruti Malu, Irma Guardiola, Alwine B. Kruisselbrink, Yvonne de Jong, Willem E. Corver, H. Gelderblom, Patrick Hwu, Torsten O. Nielsen, Alexander J. Lazar, Neeta Somaiah, Judith V.M.G. Bovée

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Safety and immunogenicity of a third dose of mRNA‐1273 vaccine among cancer patients by Anna Giuliano, Barbara Kuter, Shari Pilon‐Thomas, Junmin Whiting, Qianxing Mo, Brett Leav, Bradley Sirak, Christopher Cubitt, Christopher Dukes, Kimberly Isaacs‐Soriano, Kayoko Kennedy, Somedeb Ball, Ning Dong, Akriti Jain, Patrick Hwu, Jeffrey Lancet

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Phase I/II trial of a long peptide vaccine (LPV7) plus toll-like receptor (TLR) agonists with or without incomplete Freund’s adjuvant (IFA) for resected high-risk melanoma by Patrick Hwu, Jason Roszik, Gina R Petroni, Walter C Olson, Kimberly A Chianese-bullock, Kelly T Smith, Nikole Varhegyi, Elizabeth Gaughan, Mark Smolkin, Sacha Gnjatic, Nolan A Wages, Emily H Hall, Kathleen Haden, Sapna P Patel

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CRISPR-mediated TGFBR2 knockout renders human ovarian cancer tumor-infiltrating lymphocytes resistant to TGF-β signaling by Sanjay Kumar, Larissa A Meyer, Patrick Hwu, Chantale Bernatchez, Marie-Andree Forget, Donastas Sakellariou-Thompson, Cara L Haymaker, Rafet Basar, Yunfei Wang, Amir A Jazaeri, Ana Lucía Dominguez, Christopher Reyes, Samantha M Fix, Tamara M Griffiths, Minjung Lee

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